MDMA + Acitretin - interactions?

[vodorian]

I've recently been prescribed 20mg/daily of Acitretin for skin problems. I've noticed the massive list of potential side-effects, but obviously no mention of interactions with MDMA.
Is there any evidence of this, or am I good to be a guinea pig?

 

[PsychedelicPeptide]

I assume you mean accutane, or what is called accutane in the US. I have used a number of psychedelic drugs while on accutane without problem, but I am extremely healthy, exercise a lot and eat very well. I would suggest taking lots of fish oil before, during and after MDMA use (and probably the whole time you're on accutane) and maybe skipping the accutane for a day or two before you use the drug just to make sure your liver stays ok. Fish oil should keep liver inflammation to a minimum... accutane is "hard" on the liver, apparently.

Definitely do not drink alcohol and do nothing that could risk damaging your liver. Don't dose 1 g MDMA in 12-18 hours and expect to be ok. It is hard to say exactly how damaging accutane can be, but personally I think as long as you are taking care of yourself and not taking huge doses of accutane (think 80-100 mg/day) it is ok. Just recognize once you start using the medicine for a few months, it can build concentration in your bloodstream so like I said, taking a day or two off before using psychs is a safer idea (outside not using all together of course).

 

[omg_its_coco]

Hey I was just prescribed Acitretin for my psoriasis as well. I am pretty sure the other person talking about accutane is good information, but not entirely what you were asking because I know you didn't mean accutane. I'm on Soriatane specifically. Did you happen to roll, and how did it turn out? Did you get any side effects? What was your process as in did you stop taking it for a day or two before? Also, did you use MDMA or did you use a pressed ecstasy pill?

I would really appreciate some feedback on this, thanks!!

 

[vodorian]

Yeah I just stayed off the acitretin for the day before and the day after, took a little e less than I normally do (2.5 pills total- 1.5 then another 1 2hrs later), and I was fine. No unusual side effects, just the usual dry/painful mouth from the gurning the next day, and the tiredness.
I should say I'm on a relatively low dose of acitretin, 20mg/day. I took (ro)accutane when I was younger and the side effects were much worse.

The doctor says the acitretin may be pushing my cholesterol up, so bear in mind, it does have an effect on your liver. Try and stay off the booze (I had about 2 pints all night which was probably 2 more than I should have), test your gear if you can (check pillreports.com if you can't), let someone know what you're on and what prescription you're taking and don't overdo it.