Of the many times I have abused adderall or ritalin over the years, probably about 50% of the time after an all-nighter my throat hurts and I end up getting a mild lung infection that lasts 2-4 days. It doesn't require medication or anything and it's totally worth doing it anyway, but is there a reason behind this? My guess is that it has to do with stimulants having anti-histamine properties since all my mucus disappears when I do this stuff, and that's like the first line of defense for the immune system.