Long term damage of seroquel + cannabis combo?

[PurpleKush1]

Hey everybody, i used to take thsi combo every night for a year everyday . Adderal and alcohol in the day + weed, then pop a sero 100 mg and a blunt tothe face. It made me feel extremely uncordinated, i had CEVS if i was tired wjhen i was doing that. Like i saw a green bug spit out a human being with my eyes close, i know it seems like bullshit but it was like dreaming while being awar ethat im still awake. One time my roomate found me sittingwith legs and hands up on the sofa mumbling incoherently during my sleep. Another time when i smoked too much and ate about 300 mg of this vile shit, i passed out he came back woke me up like hey wanna smoke that joitn, i told him you cant get into my house i wont let you and passed out. He woke me up again and i started yelling you aint getting into my house muthufucka and passed out again. I noticed one of the very bad side effects of this combo is that i would get extreme restlesness in my arms and legs when dosinf heavy with marijuana. Nowadays im clean for a month because i overdid it with xanax/alcohol/ecstasy/heroin combos and i think i had pma or dxm + mdma based pill and i cant smoke weed anymore, one drag sends me into a panic attack. Ive noticed im more agressive and paranoid since doing this combos. Any hindsight?

 

[PurpleKush1]

bump?

 

[pofacedhoe]

mdma and opiate use! both of them when you go on a binge will leave you with anxiety afterwards, same with the xanax...

mdma can cause aggression/impulsivity/anxiety after a really big binge

 

[PurpleKush1]

thanks for the reply man....im better now but i wanted to know if using seroquel and weed together could fuck me up? lets put it that way, i had three steps. First step was when i was 16 after a year of binging on meth,coke and mdma i went into psychosis. I recorevered in a month and then went on what i described in the first post, everyday 50 mg or skipping a day and doing 100, smoking at least an eight of weed, drinking and popping seroquel then smoking weed before sleep. I stopped doing this because i went a little bit psyhcotic again, id wake up and be angry and lethargic, i was utlra paranoid. Since then ive noticed ihave more trouble writing and i slurr my speech alot. This never want away. I get angry very easily and im a state of total rage when this happens. Im also paranoid as fuck and cant stand crowds anymore. I would like to know, do you think its irrevesible, what can be the damage of doing adderal + weed + seroquel everyday? and third step was a month ago after the binge on xanax opiate mdma. I stopped my antypsychotics but i feel depersonalised all the time and the anger is even worse...

 

[pofacedhoe]

have you quit the cannabis? avoid mdma if you have anger as binging on it will leave you with anger problems if you are the kind to get susceptible to this (one of my friends was like that- hes fine now but never takes mdma anymore)

 

[PurpleKush1]

ive quit cannabis for 2 months, i can only smoke it if i had some kpin or xanax. i avoid mdma too now, i took a roll in january, im sure it was pma +mdma or dxm +mdma, i felt the mdxx euphoria but i was sweating way too much like 3x what i usually swet when rolling, i was ultra hot sitting in my trousers on the toilet pissing out the water in drank instantly , i couldnt walk and didnt feel my legs, i was minor hallucinations like the walls moving i couldnt formulate a coherent sentence in my mind, my heart rate was extremely fast and arythmic i seriously though i would die man i was holding on to xanax bar and something was telling me to ride it out, i eventually did, but damn! and i tried mdma + ketamine and it wasnt like that at all... this event left me with ptsd i think

 

[crOOk]

You can suffer movement disorders after long term of neuroleptics use... Chances are pretty slim at your dosage level and it usually takes many years to show up, but it could also show up years after you've ceased using the substance.
Obviously there will be rebound insomnia once you quit. If you are bipolar you might see some rebound (hypo)mania as well, at the very least you might feel agitated/stimulated even without bp.
Not sure if Diabetes is a real risk with Quetiapine, it is with some other neuroleptics. Prolonged QT syndrome is pretty deadly stuff as well, but that usually shows up relatively quickly after you start using them. Might want to have a doctor check for that, since you won't really notice it without the checkup.
Malignant Neuroleptics Syndrome can also insta-kill you, that's a very unpredictable one that can also occur on low dosages.
That's about it I'd say. There are other long term effects ofc, but these are the most common/serious ones. Best read up on it to make sure what I'm saying is correct. I'm no expert on neuroleptics, but am using Quetiapine myself at night 50-100mg, absolutely LOVE the stuff (unless it gives me akathisia which happens at higher dosages, pure hell!!!).

i felt the mdxx euphoria but i was sweating way too much like 3x what i usually swet when rolling, i was ultra hot sitting in my trousers on the toilet pissing out the water in drank instantly , i couldnt walk and didnt feel my legs, i was minor hallucinations like the walls moving i couldnt formulate a coherent sentence in my mind, my heart rate was extremely fast and arythmic

Sounds like you just had a little too much MDMA or MDA to me lol. Seriously. MDA carries a few more visual aspects and is rougher on the body, more stimulating too. My legs would feel as if I had just run a double marathon with each of my legs on the comeup.

My advice: Go see a psychiatrist, anger, psychosis and all does sound a bit like there's something going on. Wouldn't blame it on either of these two substances necessarily. It's not typical anyway.


EDIT: This does NOT belong to the Trip Reports section, it belongs to The Dark Side or Basic Drug Discussion... le sigh

 

[PurpleKush1]

You can suffer movement disorders after long term of neuroleptics use... Chances are pretty slim at your dosage level and it usually takes many years to show up, but it could also show up years after you've ceased using the substance.
Obviously there will be rebound insomnia once you quit. If you are bipolar you might see some rebound (hypo)mania as well, at the very least you might feel agitated/stimulated even without bp.
Not sure if Diabetes is a real risk with Quetiapine, it is with some other neuroleptics. Prolonged QT syndrome is pretty deadly stuff as well, but that usually shows up relatively quickly after you start using them. Might want to have a doctor check for that, since you won't really notice it without the checkup.
Malignant Neuroleptics Syndrome can also insta-kill you, that's a very unpredictable one that can also occur on low dosages.
That's about it I'd say. There are other long term effects ofc, but these are the most common/serious ones. Best read up on it to make sure what I'm saying is correct. I'm no expert on neuroleptics, but am using Quetiapine myself at night 50-100mg, absolutely LOVE the stuff (unless it gives me akathisia which happens at higher dosages, pure hell!!!).

Sounds like you just had a little too much MDMA or MDA to me lol. Seriously. MDA carries a few more visual aspects and is rougher on the body, more stimulating too. My legs would feel as if I had just run a double marathon with each of my legs on the comeup.

My advice: Go see a psychiatrist, anger, psychosis and all does sound a bit like there's something going on. Wouldn't blame it on either of these two substances necessarily. It's not typical anyway.


EDIT: This does NOT belong to the Trip Reports section, it belongs to The Dark Side or Basic Drug Discussion... le sigh

thank you alot for the reply man...im going to take your advice and go get myself checked out. I feel you on the akathasia, it happened alot to me and i aboslutly hate it lol ! bout the roll though, i have a few thing to say. I abused mdma alot. Ive eaten 10 medium mdma content pills combined with 5 meth bombs in one night, the come down from that was more pleaseant than the high of the roll i took. I always need at least two roll or md caps to get me rolling. And ive had mda pills and capsules, i know what it is. Im going to try to reformulate the experience for you. I took one pill, yes one, didnt feel shit for an hour and half. Then i sit down on my computer put some trance on,lit a smoke i start coming up in that familiar but it keeps going and it way too intense. I stood up and fell flat on my stomach. My legs were numb and twitching. i drog myself to the bathroom, my eyes were blooshot red and one of my pupils was bigger then the other one. I felt a pleasant euphoria, but there was something else coming in waves. I always get the sweats on mdxx, but this was 10 times worst, I was in a pool of sweat. I couldnt talk, i was seeing distortions in the walls and everything had a very evil vibe overpowering the euphoria. I heard voices saying kill yourself youre worthless piece of shit in my head while in the bathroom. I had random numbness in various body parts, but my legs were numb the whole time and unaporetive. I was extremely hot, my roomate was really worried. After an hour of this hell i was freezing and shaking even worse, i felt brain fried completly. All the discomfort eventually faded away, but it was a hell off an experience. I combined mdma with ketamine and once mdma with pcp and i didnt feel so fried. Since then im fucked even worse in the head, extreme depersonalisation and panic attacks. Im going to see a psychiatrist for the anger defintly. i find that clonzepam works great on me, i feel normal and happy on it and even can smoke ganja.

 

[crOOk]

Okay, that really does sound very atypical for both MDA and MDMA. Especially considering that you do seem to be more experienced than I had first thought. Regarding the benzodiazepines, I really don't wanna come across as too preachy here, but they really aren't very effective in the long run. You will build a massive tolerance, withdrawals are hell on earth (and can lead to potentially deadly seizures), your anger will be getting worse.

You are in a very fortunate position when you are one of those people that actually isn't bothered by taking neuroleptics. Definitely go ahead and mention ALL your drug abuse issues to your psychiatrist, they are there to help and no harm will come to you by doing so. Letting them know your drug habits might result in a different plan for treatment. Also, psychotherapy might do a huge deal for your anger issues. In an ideal scenario you'll have an appropriate amount of both pharmaco- and psychotherapy. These all sound like issues, that can be worked out to me. Don't make yourself crazy over having any permanent brain damage, our brains are extremely resilient!

 

[PurpleKush1]

Exactly, im completly turned off E or molly now. I actually hate neuroleptics now, i took onlazapine and decapine daily after the episode with the roll and it made me fatter and i feel dumber too. I then was prescribed clozapine but threw it in the garbage. I dont want to use them anymore. I feel you on the benzos,imma giv you a litte background on my experience with them. Since july to november i was prescribed 15 mg a month of xanax, which usually was gone in a week or two. I combined xanax way too much with alcohol, i stopped breathing in my sleep and my friend saved me. I shouldve died from the insane amounts of alcohol i mixed with but here i am . Anyways in february i ate 45 mg in two weeks, combined with heroin and alcohol. i was in a very dark place and didnt care if would die. I think i experienced mild withdrawal after all that. Now i dont want to abuse them anymore, but use them as a tool. Im aware of the dangers, i would use them when needed, lets say if i want to smoke some bud, or im feeling panicky again. But deff not abuse them anymore. Fuck that its not worth it. Im only 19 years old, if i continue this way imma be dead before i reach 30. Ive been clean from everything except the neuroleptics, alcohol here and there and i still smoke cigs for now 2 months. In 4 years, since i was 15, i didnt have a day sober. Im scared to tell this to the psychiatrist because he might give me some bullshit like hydroxysine or seroquel. I need tranquiliser and sleep aids. For example clonaz and ambien. I have horrible insomnia, im here typing and i slept 7-8 hours since friday. What do you mean by psychotherapy ?

 

[pofacedhoe]

if you have been abusing xanax i doubt you will be able to switch to using them with restraint. you're better off without a benzo addiction. the WD's get a lot worse than your recent experience...

 

[crOOk]

if you have been abusing xanax i doubt you will be able to switch to using them with restraint. you're better off without a benzo addiction. the WD's get a lot worse than your recent experience...

QFT. Please look into The Dark Side subforums for other peoples' experiences. This might be hard to swallow, especially with benzos being legitimately prescribed for people with similar issues, but many many people have been in a similar spot you find yourself in. I've been in a similar spot when making the decision to spend at least the next 6 years on a strong stimulant. A lot of people discouraged me and I've paid a very high price for sticking to my decision. Benzos are a different beast though and long term use carries a whole set of different problems!
Imho, you should at least give your plans second thoughts and talk or listen to others who have more experiences with the issue than I do. This is the right place for that. If you still consider a good plan, then I'd say go for it. I really hope you reconsider though when you hear what hell others' lifes have become by trusting into these seemingly helpful meds. Whatever you decide to do, I hope it all goes well! The Dark Side subforums are a great place to visit when finding yourself in a tough spot. There's no other like it on the internet in my experience.

Edit: For how long have you managed to get off all meds, both antihistamines and antipsychotics as well as benzos and weed? There's a chance your horrible insomnia, which I no doubt believe you have a very difficult time dealing with (I myself used to follow a 72h/12h wake/sleep cycle for several consecutive month), is in fact a lingering rebound phenomenom. People have reported those to last as long as 6 months after neuroleptics withdrawal.

 

[PurpleKush1]

hey man, sorry if i didnt reply earlier but i have no internet access atm so im probably going to reply next monday lol. Out of curioisty, what was the stimulant you were on and what side effects you had to deal with? because the drugs i abused the most are stimulants (coke,meth,amphet,mdma). And ive been off everything now for a month, and i have panic attacks daily, i have some clonazepam but a limited supply, if i take it it helps but the next day is hell. this i why im taking about psyhcoterapy. and i check the dark side forums regurlaly, they do provide help in fact. Thank you for all your very useful replies,crook!