The Legendary oral hybrid Brompton Cocktail
*Methadone 80mg
*Ritalin 60mg IR
*Valium 30mg
*Lyrica 300mg
*Cannabis 10mg oil
*Ethanol / Jin 3oz
1 hour ticket to heaven ……Cocaine & Ketamine 50/50 little lines every fresh Jin cocktail before having a premium Belmont cigarette on the patio. Roaring fireplace and a good movie, all cozy on the couch with my GF while cleaning my Colt 1911 .45 on the coffee table lol……Happiness, is a WARM Gun lmao (Beatles song) ….but no, really…it is lol. The smell of a freshly cleaned & well oiled firearm smells like my woman’s warm pie, ready to F@CK ….gets me all excited lol
I knew a pharmacist who opened his first compounding pharmacy in the 1960s. Back then they used the ORIGINAL Brompton Cocktail and it was even in the BNF.
*Diamorphine (H is stable enough in solution as long as the medication is intended for immediate use)
*Cocaine
*Tincture of cannabis
It was explained to me thus.
^The heroin ensures the patient is in no physical or emotional pain.
*The cocaine offsets the sedative/hypnotic effects of the strong opioid AND synergy with the opioids produces powerful euphoria
*The tincture of cannabis means that when the patient sleeps, they will be spared any nightmares.
But over the decades and due to various social, legal and practical reasons, each one of those three important SOUGHT effects have been substituted for cheaper, easier to obtain and longer lasting alternatives. Doctor's who seek to dispense diamorphine or cocaine now need a special licence. I'm not certain when tincture of cannabis was removed from the BNF but evidently it was in there at the time.
BTW I'm one of the few people who is open minded about drugs but just dislike the effects of snorted or smoked cocaine to the extent that if it's offered freely, I will say no. But as an experiment I placed a gram of cocaine into a 1l bottle of Coca Cola* and the effects were far more long-lived and far more enjoyable. It's rather an expensive experiment but I came away considering it a far better ROA.
*Other brands of Cola are available at millions of outlets worldwide. The brand name 'Coca Cola' is owned by The Coca Cola company and it's choice was based on convenience and availability. I have no reason to believe the subjective effects would differ significantly if I had chosen another brand of Cola. The Coca Cola Company does not support the use of controlled compounds.
No conflict of interests to declare.
BTW as
@Dextro .45 points out, morphine has very poor oral bioavailability due to extensive fist-pass metabolism. In healthy adults researchers give figures from around 21% to around 24%. But there are super-metabolisers for whom morphine is almost inactive orally. I find it interesting that the figures for diamorphine are slightly higher with a range of 22.9% to 29.4% being given in different studies. So MAYBE part of the reason diamorphine was preferred?