TDS Kicking Mirtazapine for good

Flynnal

Bluelighter
Joined
Aug 14, 2012
Messages
849
So, two weeks ago I decided to kick Mirtazapine for good. It was making me irritable for no reason, in spite of getting decent sleep. I was always feeling like I could have felt better, but because I was always slow and lethargic when using this stuff I could not function to my full capacity, and would be moody and get angry at people for silly little things. I remember going off because someone gave someone a piece of candy before lunch break and told me they would give me a piece after lunch and then told me it was no big deal when I asked them for the candy after lunch break so I went right off which in hindsight was really stupid. Today if the same thing happened I'd just think...meh...and shrug it off, like a normal person should. It was really no big deal. Yes, I hate being bullshitted to, but it was no big deal as the guy said it himself. Now, I see why I was carrying on. It was the Mirtazapine affecting me in many ways.

The trouble with Mirtazapine is that it works on depression for a while, but then it craps out intermittently, leaving me feeling terrible, obsessive and thinking stupid thoughts, and yet I needed to take it as I was COMPLETELY unable to sleep without it.

It was also making me anxious too, because I remember feeling awful about things I couldn't change. That is anxiety to me, feeling bad about things you should be shrugging your shoulders about, since you can't control it and should be focusing on the future and most importantly the present.

So, I went onto Agomelatine for 10 days to reset my sleep pattern, this ALLOWED me to sleep whilst the Mirtazapine was being metabolized out of my system completely, then stopped taking Agomelatine since a week ago, since that, too, seems to screw with your sleep pattern on a long-term basis, from personal accounts I've heard about it.

Day 1 - no sleep AT ALL.
Day 2 - 2 hours of sleep, no dreaming.
Day 3 - 1.5 hours of sleep, no dreaming.
Day 4 - 2 hours of sleep, no dreaming. Itchiness, especially the legs.
Day 5 - 3.5 hours of sleep, a short dream. Terrible itchiness, the legs and feet.
Day 6 - Today - 4 hours of sleep, a longer dream than Day 5. Itchiness till there, but may improve.

Day 7 - ?...I will update this thread as my crisis progresses from terrible to much better, but I've been told it will take many months (perhaps even 3 to 6) before my sleep is back to what it was when I started using Mirtazapine back in the first quarter of 2004, which was basically 10 years ago give or take a couple weeks.

Anti-depressants - seriously, leave them alone unless you really have serious suicidal thoughts. Short bouts of depression without suicidal thoughts I'm told is completely normal and affects 1 in 3 people throughout their lives over a 5 year period. There's no point trying to fight that because you're fighting human emotion in response to loss, or experience of pain due to empathy of another's suffering, and general grief. You CANNOT avoid it, so you should not fight it with medications that are well known to destroy your sleep architecture.

This drug, which once saved me, has basically gone on to ruin my life. Now, it's going to be a long road to recovery of my faculties, I need to sleep, and I'm getting meagre amounts as it is. It will improve no doubt, but please, if anyone is thinking of touching this stuff, make sure you understand my experience as a serious warning of what can happen when you decide to come off it. And no, slowly tapering off it won't work, do a quick taper. Go from say 60 to 45, then to 30 then to 15 over a period of say 1 month, then STOP. You will need to take Agomelatine (Valdoxan) for 7 to 10 days, after stopping Mirtazapine because you won't sleep a wink. After 7-10 days, STOP the Agomelatine, or it too will screw up your sleep architecture.

You will have trouble sleeping, yes, and you will need to take hot baths, hot showers, take some magnesium supplements (certain types) and listen to calming and peaceful music in a very dark room. Sugar and caffeine are big NO NOs. You need to do something for the racing thoughts and the lousy feeling you'll experience for about a month before you begin to start feeling better. It may not make you sleep any better but it will provide the right environment to help sleep.

I feel like kicking the Mirtazapine will be like my new anti-depressant - but one that will not require me to constantly refill prescriptions and be putting chemicals into my body that are not really supposed to be there.

As I said, I'll update this thread for all and sundry and write a journal of my progress.
 
This is interesting. I myself have taken it for years due to insomnia/anxiety (dose range 7.5-30 mg) and thought it would be relatively easy to withdraw from since I havent stumbled across reports of any major difficulties until this. Never missed a dose so have no idea of the reaction. It has not done anything for my anxiety issues but ive found it best as a sleep aid, so it would be expected that insomnia is the worst symptom.

Do you have first hand experience that tapering further down wont work? I was thinking tapering to 1-2mg before jumping off for least discomfort. Still the sleep inducing effects seem to be about the same even at very low doses, so im not sure if tapering is really necessary.
 
I was on Remeron(Mirtazpam)for some years.
i don't remember much since i was using heroin also at the time.
the Remeron made me slower,I can't remember any serious withdrawal,
but again,I was using crack,dope and benzo's on and off so
the mirtazepam probably didn't gain any effect.

your story sounds horrible,I'm so sorry,it is really good you're
putting this info out there.
people take AD's so much,docs prescribe SSRI's for nothing.

major luck and get rest.
 
One of the things that I try to do when I am having bouts of severe insomnia is to focus on resting rather than sleeping. It isn't a substitute but it helps take the added layer of anxiety about not getting enough sleep off of all the other impediments to sleep. If I feel my thoughts getting cenetered on the anxiety ("I've got work in 4 hours, I HAVE to sleep, This is so bad for my health, etc.") I try to center on just breathing and relaxing telling myself that relaxing is my only goal.8)
 
Well, it looks like my sleep patterns are starting to return to normal.

It'll take another month or so, at least, before they will return to a better sense of "normal".

I'm now getting about 5-6 hours, sometimes it's broken, other times it's not. But usually I get up around 3am-4am to urinate, but that's about it. I usually nod off at 10-11pm, but go to bed around 9pm, so I'm laying there for an hour. I relax using certain thought patterns. When something bad gets in my thought I think "well, let's think about something else, shall we? how about thinking about being on a boat on a calm river".
 
Top