Subject says it all. If so, name the drug(s) and the reason(s). Is it because you feel you need a sitter to keep you safe, you need someone to report a potential OD, or is it because it's a drug you feel is only useful socially? The only drug I place in this "never alone" category is MDMA. Perhaps if I didn't experience horrible after effects, I'd give it a go sometime just to see, but it doesn't really seem worth doing alone for me...