is the high from IM administered drugs as good as the high from snorting?

[Randy Bobandy]

is the high better or worse with I.M. than with intranasal? specifically hydromorphone.

 

[PotatoMan]

The bioavailability should be higher meaning more of the drug in your system meaning a more potent high, so sure.

 

[《Plasticity》]

IM is always gonna be better, bioavailability is second to IV with a timeline closer to rectal administration IME.

 

[Keif' Richards]

As others have said, the IM route is second only to IV. I was under the impression that bioavailability was still 100% or close to it with this route, although I could be wrong. When I have bruised/scarred veins in the past I've been forced to go IM with heroin. The only real difference is time of onset in my opinion, which will vary from 5-15 minutes depending on the person and the muscle used. Although I have never had any problems personally from IM'ing, many on here mention an increased likelihood of infection and abscess when compared to IV and the masses have never been wrong. That's just something to look out for.

Now, assuming you're working with hydromorphone tablets, there is obviously a heightened safety risk. Even if you know how to prep them and draw a clear solution, it's still not safe. I would avoid it if at all possible, as I would avoid using needles with any substances extracted from pills, but hey, it happens all the time. If you decide to go through with this ROA, be aware of the bioavailability differences (google,wikipedia etc.) between IM and your current route, use aseptic technique - washing hands and the site - using a clean workspace - filtering at least twice and preferably with micron sized filters - clean hypodermic etc. this always applies, but there's always room for this knowledge. Also, in case you aren't aware, you should moisten your filter before drawing.

Again, this is certainly not safe, or good advice, but if you are to go through with this, minimize risk as much as humanly possible. It's a sick statement in a lot of ways, but I IM'ed a hydromorphone prescription after major surgery and enjoyed it each time. You get to experience that amazing rush for a few more minutes, although at a bit weaker of a kick. I was sick and desperate though. "I sure as shit was not going to "waste" hydromorphone by taking it po." I'm lucky my quadriceps still work with the amount of foreign shit I've put in them. Make wise choices, unlike mine.

 

[《Plasticity》]

IV. I was under the impression that bioavailability was still 100% or close to it with this route, although I could be wrong

It's typically in range of 85-95%, close to that of IV but sometimes falling a bit short. For example IM ketamine has a bioavailability of about 93%. IM Midazolam has a bioavailability of about 90% whereas IM heroin has a bioavailability as low as 85%.