Opioids Is Snorting Oxycodone just as effective?

[Altered Perception]

I have been taking Oxycodone last few years for chronic pain, however I have never snorted it before. I am now considering snorting it because I have recently developed digestive problems such as Gastroparesis which causes delayed gastic emptying and delay the effects of the Oxycodone by up to 5 hours.

I have 20mg capsules of pure Oxycodone Hydrochloride and it appears fairly concentrated as the capsules are quite small. If I snort 80 mg of this will it work just as effective without being delayed by my digestive problems?

Out of curiosity I was also wondering whether grapfruit juice would have any influence when you snort substances that would normally be effected by the P450 liver enzymes? Also what if you snorted opiates like Tramadol that is a prodrug and require the liver to convert it into an active form, are prodrugs ineffective when snorted?

 

[sweetstufflover]

[I won't condone IV use] In your case, snorting might be worth the shot. But remember: The BA of oxycodone when snorted is lower than when consumed orally (that's what I've read everywhere).

[Not going to condone IV use]

 

[HeadphonesandLSD]

I'm about to call it a night so excuse me for begin short, I'll check back when I wake up.

I have 20mg capsules of pure Oxycodone Hydrochloride and it appears fairly concentrated as the capsules are quite small. If I snort 80 mg of this will it work just as effective without being delayed by my digestive problems?

Yes, it will work. I don't have the BA numbers on hand but its close to begin the same % of the drug getting into your blood stream no matter if you snort or swallow when it comes to oxycodone. I know someone will come a long and correct me, but really its about the same IME.

The main difference will be onset and duration, if you snort it will come on faster but won't last as long. Keep in mind that you're going to lose a little in the process. If you inhale too hard when snorting the pill parts of it will go down into your lungs never to be seen again (yes, its very bad for you). Your goal should be snorting lightly enough that most of the powder stays up in your nose for as long as possible.

That said, there will be a drip so you will be getting a portion of it via the stomach assuming you swallow the drip instead of spitting it out.

Also note that snorting a pill isn't exactly that pleasant, is horrible on your nose, will eventually cause a sinus infection, and comes with a whole other set of bullshit. You can also get addicted to the entire act of crushing the pill, making lines, and snorting it. Strange as it sounds with time you'll come to love the burn and the drip. -,-

Out of curiosity I was also wondering whether grapfruit juice would have any influence when you snort substances that would normally be effected by the P450 liver enzymes?

Yes this will work no matter the ROA.

Also what if you snorted opiates like Tramadol that is a prodrug and require the liver to convert it into an active form, are prodrugs ineffective when snorted?

Snorting tramadol is a really bad idea. While snorting pills in general isn't that smart, there are a few where its the way to go (like Opana) and others where its useless (like xanax). Tramadol falls in the useless section. Please do some research before you start putting random things up your nose.

Also, don't assume you can handle 80mg right off. Start slow since you're trying a new ROA and find the right number for you. In addition to begin a bad idea railing 80mg all at once is just going to pack so much stuff up there that most of it will not be absorbed and will just go down your throat making it no better than swallowing.

One last thing: Can you consult with your doctor and see about getting put on something else? Have you considered a transdermal patch?

 

[ms4104]

I have been taking Oxycodone last few years for chronic pain, however I have never snorted it before. I am now considering snorting it because I have recently developed digestive problems such as Gastroparesis which causes delayed gastic emptying and delay the effects of the Oxycodone by up to 5 hours.

I have 20mg capsules of pure Oxycodone Hydrochloride and it appears fairly concentrated as the capsules are quite small. If I snort 80 mg of this will it work just as effective without being delayed by my digestive problems?

Out of curiosity I was also wondering whether grapfruit juice would have any influence when you snort substances that would normally be effected by the P450 liver enzymes? Also what if you snorted opiates like Tramadol that is a prodrug and require the liver to convert it into an active form, are prodrugs ineffective when snorted?

If those capsules were made up by a chemist at a pharmacy there is a godo chance there is an additive in their to deter people from sniffing or shooting. They usually add something to the oxycodone hcl.. like if you had your pharmacist make you up some oxycodone IR's they are not just pure oxycodone hcl usually as far as I know

As far as sniffing oxycodone goes.. you will get mixed opinions..and some BA numbers.. my opinion is that sniffing works better than oral in every way. I alwyas felt like oral was a waste but if you pay attention to the BA numbers you would think oral would be the way to go. It comes down to personal preference but most people I know either sniff or shoot very few take orally unless it was like the 1st time dosing. The reason for this? I am not sure.. I am pretty sure its not peer pressure or that they are trying to be coo lol. I think its becuase they think it fucks them up more.

 

[Altered Perception]

If those capsules were made up by a chemist at a pharmacy there is a godo chance there is an additive in their to deter people from sniffing or shooting. They usually add something to the oxycodone hcl..

The brand name of the Oxycodone I use is "Oxynorm" and it is manufactured by a pharmacutical company called "Mundipharma". I read through the product guide and it is an instant release type Oxycodone and very pure. The product inormation says...

OxyNorm capsules contain either 5
mg or 10 mg or 20 mg, of oxycodone
hydrochloride, as the active
ingredient.
The inactive ingredients in OxyNorm
capsules are microcrystalline
cellulose and magnesium stearate.
http://cincottachemist.com.au/productcmi/74141.pdf

This is what the capsules look like...

http://oi39.tinypic.com/23lhzsg.jpg

 

[rob007]

i read everywhere that prolonged insuffulation of microcrystalline is dangerous to your health. especially your lungs!

 

[crashg]

I agree with HeadphonesandLSD IME anyways...I was on the 15mg pills for a few months and would sometimes snort them as I also have a bad stomach but like is stated here continuous use up the nose is not safe at all. Maybe talk with your doctor about a different form of your main meds like maybe a patch or something. I am also considering this myself for my next doctor visit which is here soon. I have IV'd these 2 times only thank god and it was an awesome rush but after doing my research on here I will not do this with pills anymore until I have the proper supplies. Like a micron filter. It's so hard to decide on what to do and I feel your pain bud as its like you don't want to hurt but then you also don't want to mess your stomach up anymore either. It's like no matter what you do your going to mess something up! Keep us posted on what you decide tho! I hope other people help out with information as I am curious about what to do also!

 

[Altered Perception]

Thank you all very much for the advice, especially HeadphonesandLSD for his detailed response. I wasn't aware that the non-active ingredient in my Oxycodone known as microcrystalline cellulose could be harmful but now that I am aware I will no longer be snorting it as I read that "microcrystalline cellulose" can cause silicosis.