• MDMA &
    Empathogenic
    Drugs

    Welcome Guest!

Is E sexually transmitted?

C10H12N20

Bluelighter
Joined
Jul 1, 2004
Messages
259
Neurochemistry of sex(formerly: "Is E sexually transmitted?")

Theoretically if you can find mdma in saliva, then you can find it at other places in your body, which would mean that E could be sexually transmitted...

The reason I ask is my buddy had a bunch of pills (5-10) the other night and his gf did not. He said they had sex and then he said she rolled her ass off and her pupils were dilated, but she did not have any pills. At first I laughed, but then on the second thought, I guess it is theoritecally possible, if the dose is high enough... Has anybody had experience like that? Any thoughts?
 
Last edited:
While its possible if the exchange of bodily fluids (saliva, blood, sexual secretions) occurs to pass a small amount of MDMA, the quantity would be minute, and far far below the level required to create a high. For that to happen, 10% or more of the consumed MDMA would have to end up in the semen, which it doesn't, and all of that go into making a high (ie assuming perfect absorption, no wasting).

If she drank enough of his urine, but then thats a different level to the sex......

More likely it was placebo and natural neurochemicals related to sex. A goodf sex sesh and someone high with you would be a powerful combination I imagine.
 
>If she drank enough of his urine, but then thats a different level >to the sex......


Haha, he's been busted...
 
OK so he tells me he had like a two hour blowjob and the roll she had was very short, like 2-3 minutes, and then later she rolled again, and went to see her pupils they were dilated, but then she checked 5 minutes later it went away and she went back to normal, but he says she described that she had a very intense roll...
 
AlphaNumeric said:
More likely it was placebo and natural neurochemicals related to sex. A goodf sex sesh and someone high with you would be a powerful combination I imagine.

I totally agree. Most people don't think about the chemical reactions going on in your brain during an orgasm. I think it's proven that when you have an orgasm a decent amount of serotonin is released.
If you were able to sustain this feeling, I believe it would be almost exactly the same as being high on MDMA. While lots of people don't agree with my theory, no one has convinced me yet that it isn't true.

Also, the vibe of being around someone you care about who's on E can rub off on you.
 
s0nic said:
I totally agree. Most people don't think about the chemical reactions going on in your brain during an orgasm. I think it's proven that when you have an orgasm a decent amount of serotonin is released.
If you were able to sustain this feeling, I believe it would be almost exactly the same as being high on MDMA. While lots of people don't agree with my theory, no one has convinced me yet that it isn't true.

Also, the vibe of being around someone you care about who's on E can rub off on you.

I actually think that it is dopamine/norepinephrine that provides the feeling of orgasm (and roll) and serotonin comes in 2-3 minutes later... serotonin generally inhibits sexual desire (judging from effects from SSRI)... anyways, just wanted to clarify that, but other than that, I think your point is valid, cause the feeling on E is pretty close to when you have sex... I am just not sure about dilated pupils (they can dilate from excitement too I guess), it's not like her pupils were dilated for long time... Let's also not forget, my buddy was tollally e'd out the other night ;) who knows what kind of freaky shit those two were doing...
 
^^
Thats a good point. However maybe that's why males can't orgasm multiple times at once. Once you orgasm.. serotonin is released and it inhibits you from performing anymore?
 
I think you are right... From what I gather, serotonin basically tells the body that everything is OK. It is like the main green light "all systems good". When everything is OK, that means you are not hungry(hence anorexic properties of 5HT), you dont want sex (hence asexual, but sensual feeling on E), etc... Bottom line: when you are happy you dont need anything you wanna live in the moment. That's how I feel right after sex. It's like I could be there in that moment for the rest of my life. The thing that makes MDMA amazing is that it also produces DA and NE, so on top of feeling everthing is ok, one is loved up and can experience intense pleasure. Hence SNRI are much better than SSRI for people who have problems with sexual desire...
 
as for the pupils, i would guess it was from having her head buried between someones legs for two hours that caused her pupils to dilate

unless of course the sun really does shine outta this guys ass :)
 
i have heard of this on BL before, some dude got a failed drug test because of it.. dont know how true it was/.
 
Everytime i have sex or get a blowjob my pupils dialate to the max right after i orgasm and it last for about 1-1 1/2 minuits. Does this happen to anyone else?, sorry for the abstract.
 
My pupils tend to dilate for a little while after orgasming too...

I think people are being a little to quick to jump to the conclusion that it must be the pills -- as has been said an orgasm is a powerful thing, and can certainly influence your brain chemistry for a short time

s0nic -- in regards to your theory, the orgasm isn't the same as the MDMA high. For a start, there's less 5-HT2 receptor agonism (such as with MDA). People assume that serotonin and dopamine are pretty much the main chemicals in your brain, and they're not. They're modulatory neurotransmitter systems. Glutamate is the primary excitatory system. Then there's all sorts of other interesting things going on, like with vasopressin and oxytocin for instance.

Moreover most people report the MDMA high is very different from an orgasm. Sure body sensations are heightened, but MDMA sure doesn't feel like an orgasm to me.

A lot of people here are also assuming that serotonin release is responsible for the orgasm, and AFAIK its not. I don't have time to look, but if anyone finds any references on the neurochemistry of orgasms it would be worth posting
 
Ok, I'm not going to defend my theory because it's just an idea I had. I obviously don't have any scientific evidence to back it up. I think it would be really interesting if someone finds info on the neurochemistry of an orgasm.. (if this information is even known). I've tried to look it up before without very much success.
 
VelocideX said:
A lot of people here are also assuming that serotonin release is responsible for the orgasm, and AFAIK its not. I don't have time to look, but if anyone finds any references on the neurochemistry of orgasms it would be worth posting

One of the primary effects of orgasm on your nervous system is the close tie between your sympathetic and parasympathetic nervous system. These two systems work entirely detatched from one another during all other actions: digestion, sleeping, moving, et cetera. The cross-over between whichever system is operating in the foreground is considerably slower at any time with the exception of orgasm; then, the switch is quite fast, and that itself throws your body for a loop.

As for serotonin, as stated, it is a very important neurotransmitter in the body; it has 25 +/- receptor proteins throughout your nervous system. Also, when serotonin attaches to a receptor, it doesn't let go. The molecules have to be pulled off in order to make whatever reaction is occuring within the postsynaptic cell cease. (On a side note, this is why MDMA is so abusive to serotonin receptors in the body... it wears them out like a maufugger.)

I'm not entirely certain, but unless I'm mistaken (which I probably am), orgasm only releases a relatively large quantity of both serotonin and dopeamine. Epenephrine/Adrenaline and norepenephrin/noreadrenaline I'm not so sure about. But those dopeamine and serotonin releases both end up stimulating the reward center in your brain, which coincides with the basic desire/necessity to procreate; speaking in terms of basic primal survival, orgasm is tied in with procreation, and procreation = propagation of the species = good.

Here's where it ties in: the drastic switch between your sympathetic and parasympathic nervous system at orgasm has just thrown your body for a loop; also, there has been a quantity of serotonin and dopeamine dropped into your system. Dopeamine is already giving you a pat on the back, but when you toss the really clingy serotonin into the mix, I'd imagine for a short while at least, your body is going to allow the serotonin to remain attached to the receptors for longer than usual.

When this happens, your body is going to realize that there is less free serotonin floating around your nerve synapses than normal, and the cell (are they cells or glands?) that store serotonin are going to release some to equal it out. When the dopeamine high-of-sorts wears off, your body will then realize there's too much serotonin, and start reclaiming it. But still, that's enough time for serotonin to take your body by storm for at least a few minutes, hence the potential for something of a short MDMA-like high/buzz.

How's that sound? I feel kinda smart after writing all of that. :)
~Decibel
 
Aaaahh

Yep, Decibel's on the right trail.

At the point of orgasm, your brain experiences a huge flood of dopamine and endorphins, and that's why it's so fucking pleasurable (pun intended), the post-orgasmic state is due to a secondary release of serotonin and oxytocin.

Dopamine and endorphins are important for reward pathways so that you'll be encouraged to repeat the experience, and serotonin and oxytocin are important in getting you to bond to the person you have just had sex with (so you'll hang around and help during the pregnancy and rearing of the child). All products of evolutionary biology to encourage you to pass on your genes. It just so happens that certain drugs can reproduce naturally occuring states.

I know this bit might sound like a load of bollocks to some people, but that's why, everything else being equal, sex with someone you love is so much more satisfying than a one night stand.

Isn't evolution wonderful?
 
Evolution is a fascist process of carrot and stick programming that we need to break free from, IMO. In many ways I consider it to be less than wonderful. :-)

Back on subject, though... I don't know whether or not E is transmitted in sexual fluids, but I certainly tell a lot of people that it is.
 
An orgasm is the biggest legal blast
of dopamine that we can engineer. Last fall a Dutch scientist, Gert
Holstege, announced that his brain scans of orgasm resemble the brain scans of a shot of heroin. http://www.jneurosci.org/cgi/content/abstract/23/27/9185
But, as Quartz and Sejnowski note, "more is not better"
when it comes to dopamine. In fact, rats wired to
stimulate (at will) the neurons that dopamine stimulates in the
pleasure/reward center buzzed themselves to death, without pausing to eat or investigate sexually receptive mates.
 
I was just thinking about this today, and have come to the conclusion that this post wasn't very intelligent on your part (C10H12N20). I mean, aren't you cabable of any common sense?

It's stupid to think that MDXX is sexually transmitted.
 
Top