how dangerous is mixing ativan with clonazepam?

[Alfonso_Camarga]

i take 1mg clonazepam in the morning and one in evening, would it be dangerous to take .5 ativan with evening dose?

 

[Survival0200]

Benzos are quite safe by themselves. It's hard to OD by taking just them. Of course, nothing good ever comes from taking too much benzodiazepines.

I think it's safe to combine 1 mg + 1 mg clonazepam with 0,5 mg lorazepam (Ativan).

 

[Azed]

Like @Survival0200 said, benzos are quite safe and hard to OD on, at least compared to barbiturates and other similar depressants. When I was still working in pharmacy we had a patient on alprazolam 2mg twice daily and clonazepam 2mg twice daily and our pharmacist saw no problem filling it for them every month.

So I would say that it won't be dangerous, especially if you have a tolerance to benzos in general.


Best wishes and stay safe!
Azed

 

[Coffeeshroom]

How dangerous is it to mix a shot of tequila with my beer?

 

[Azed]

How dangerous is it to mix a shot of tequila with my beer?

Instantaneous death.

 

[Tomer]

it’s safe but beware of withdrawals if you take too much over time. That’s all you have to worry about. It’s not a bad combination at all for you to take. Just be safe.

Winds and travels

Tomer

 

[Parabolan]

Should be safe at those doses.

 

[Dextro .45]

Isn’t dangerous to combine any benzos, in correct doses….2 examples

Clonazepam 0.5 - 1.0mg - Anticonvulsant, anxiolytic
Lorazepam 1-2mg - Anxiolytic, sedative,

Diazepam 10-20mg, Anxiolytic, muscle relaxant
Alprazolam 1-2mg, Anxiolytic, antidepressant

Even adding that to an opioid tolerant patient…
Oxycodone 10-20mg IR / Dilaudid 8-16mg IR (1 or 2 tablets)
Ritalin 20-40mg IR / Dexedrine 5-15mg IR
Diazepam 10mg
Alprazolam 1-2mg
Pregabalin 150-300mg
Clonidine 0.1mg (half a scored tablet even)

Each Benzo has a particular advantage over others, Valium (Anxiolytic & Muscle relaxan) Klonopin (Anticonvulsant & sedative) Xanax (Anxiolytic & antidepressant properties) ….each in a low therapeutic dose, 2 benzos combined would have a more broad range of subunit activity / more effective advantages than a single drug. Adding a gabapentinoid such as Lyrica and something like Clonidine 0.1mg which lowers BP & HR, possessing robust anxiolytic & sedative properties (even half a scored 0.1mg tablets is effective in a cocktai)

bodyweight, tolerance, DDI’s, individual metabolis, fasted or fed state, etc…..all can come into play.

the lowest effective dose (low therapeutic dose) with each substance is ideal as a combination would/could have a potentiating effect