You know... its weird, but now that I think about it.. I have never been much more than just dope sick when I still did, H.. and other pharm opioids too. I used to be around sick people, and I would never actually feel sick as long as I had H/opiates in me at all times! I have a fast metabolism, especially with IV opioids, like oxy and dilaudid.. really IV H and opana too, wasn't too long lasting very often for me... I would be dope sick within 1-3 hrs usually and just need to take more of them constantly and, thinking back it is kind of odd to me, how I just never seemed to pick up any viruses in my time doing opioids.. even with a partial agonist like subutex, which I take now instead.. I still don't get sick very often.. ever really.. I remember prior to opioids entering my life, I would seem to catch all kinds of viruses.. now I don't lol. I think some opiates/opioids definitely have a rather strong impact when you are sick, obviously some more than others, and also very different based on the ROA your using them.. and how much you are using.. But I mostly did oxy, dilly and H, except for the super rare Opanas ER and IR that only like one person I knew had, sometimes... rarely.. and when I was on opiates (and now on sub too), even if I did get sick, stopped me from feeling much of any symptoms from most viruses, if I had enough to keep me from going into WD of course.. idk its probably different with everybody.. but I know they can be helpful, in some cases, when sick..