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Alcohol Herbs, drugs, etc... that keep you from getting as drunk while drinking alcohol?

The Soviets (ironically) spent billions of rubles trying to come up with something that would do just that- allowing their agents to get their targets roaring drunk while remaining sober themselves.

Didn't work. Came up with Antipokhmelin...which arguably helps with hangovers.
http://en.wikipedia.org/wiki/Antipokhmelin
 
I've never understood this line of thinking, ever. Why even drink if you dont want the effects? If you dont want a buzz, dont drink da booze. I only drink for effect, I dont particularly enjoy the taste of beer, liquor, wine, i'd rather have ice tea or lemonade, but they dont get me drunk. Just my opinion.
 
There must be some thing out there....right?
Thanks.<3

It's called Adderall. Watch out though, it's so efficient that you can intake dangerously high amounts of alcohol so keep track of how much you drink because you are very likely to die before you even get drunk or feel the effects. Doses for this are 15mg IR but keep in mind that it's super IMPROPER use of the drug. If you want this just so you can impress your buddies to show them you're tough notch and don't get drunk over a can of votka, make sure you reserve a body bag and a nice warm coffin for you to journy in.
 
There must be some thing out there....right?
Thanks.<3

The problem with ethanol is that it's such a messy molecule, you'd probably have to come up with a nice cocktail of stuff to counter the full effects. The ones we know about, at least.

Flumazenil, for instance, works great for benzo overdose but does not work at all for ethanol from what I hear.

I would wonder, of course, if combining this with something like an NMDA agonist would help at least some of the symptoms (the sedative and muscle coordination issues, at least). But... a drug to counter the brain effects anyways would probably leave you with none of the pleasure, but all of the body toxicity of the metabolites. So you'd be sober and then get a hangover? Quite possible. Doesn't sound fun.
 
I used to find that a few lines of coke would help to sober me up fairly quickly which just enabled me to carry on drinking for longer without getting absolutely pissed.
 
Drink and do a line of cocaine and repeat throughout however long you want to drink. Shit you can drink 12 shots of yager or any liquor and do aline or two of some good stuff and you'll feel sober as a nail as far as being drunk goes. You'll be ready to drink more and more. Based om how much you drink tho and how long your up, expect be recovering for a whole day. Definitely don't miss cocaine and alcohol but it is a awesome xombo until you try and sleep with your mind racing and broke as fuck. Gettin way off topic but 100% that shit sobers ya up.
 
^ this is really shit advice. stimulants, no matter which ones, do not sober you up. at all. nothing does except giving your liver time to metabolize the ethanol. you may subjective feel a bit more sober, but you really aren't. and coke/alcohol combinations have led to some monumentally shitty decisions on my part ('oh god, why did i fuck his sister?') and i'm sure i'm not alone with that. if you need to sober up, sleep it off. nothing else will help.
 
Not to mention that cocaine, when combined with alchohol in ones system creates Cocaethylene which is supposedly longer lasting than cocaine and highly euphoric. Anyway, since when did using blow sober one up? You may not be falling over drunk, but you'll just replace it with being obnoxiously talkative and aggressive. The only thing I EVER heard that reduced alchohol intoxicating effects, is Naloxone, and some people say suboxone does too, but combining an opiate with another depressant is a horrible idea too.
 
I used to take Naltrexone 50mg per day and it nothing to "sober" me up or allow me to drink more or less. Seemed to cut down on the urge, but when i did decide to drink, i drank and got drunk????
 
Naltrexone does reduce the cravings for alcohol - but doesn't have a direct effect on alcohol itself, so you will
still get just as drunk.

The only way to get less drunk is to drink less, and to reduce the hangover, the best things to drink are either
'neutral spirits' (Vodka rather then Whisky or Brandy), or to drink beer... Red wine is one of the worst things.
This is probably as Vodka has very few hangover-causing impurities, but is so concentrated you can get
easily dehydrated, whereas beer / lager has impurities / hangover-causing molecules in it, but it is so dilute
that the dehydration is much less than spirits. The best / least hangover-causing way is to drink Vodka mixed
with fruit juice or whatever, and then drink lots of water before going to sleep.

In the longer term, liver damage is a major concern. However, look up acute and chronic pancreatitis... this
makes liver disease look like a walk in the park in some ways. Another major problem with alcohol is
nerve damage - this can occur as the direct toxic / poisonous effect of alcohol (causing problems such as...

Alcoholic Neuropathy - loss of sensation to distant parts - usually toes and fingers, slowly travelling up the
legs; this is combined with problems with blood supply caused by other autonomic nerve damage, so your
toes etc can become deprived of blood, and painless, so become easily damaged, and can lead to
amputations.

Cerebellar damage - this is the balance organ in the brain, and can stop you walking properly, and make you
fall over all the time.

Alcoholic Dementia - this is when the alcohol literally kills cells in the brain and eventually you get an early,
incurabale dementia.

Wernicke's Encephalopathy - this is a very scary, but importantly a TREATABLE problem. If you drink very large
amounts of alcohol, you tend to eat less food... so you get less vitamins. Thiamine is a nutrient in food that is
very important in processing sugar in your body to turn it into useable energy. In chronic alcoholism, you eat
less food, so have less Thiamine, and also your digestive system changes so that you absorb MUCH less thiamine
than usual (so even if you take thiamine tablets, most of it passes through without being absorbed).

If a chronic alcoholic does a detox suddenly, and reduces alcohol intake (hopefully taking Diazepam under prescription
from a Dr), then they will start eating more food. Your body (and especially brain) will have started running
on Alcohol rather than Sugar (literally)... The sugar goes to the brain, and it breaks down into a toxic acidic substance.
This is then broken down using THIAMINE to a harmless substance... as the Thiamine is deficient in chronic alcoholism,
instead the acidic substance builds up everywhere... in Wernicke's area of the brain, the cells are very sensitive, and
can be easily killed by this. The end result is something called 'Korsakoffs Psychosis' - which isn't psychosis, but is
a syndrome where you have NO ability to lay down memory any more. You can remember for the past 30 seconds,
and remember your life story up until the time you have *untreated* Wernicke's encephalopathy, but after that point,
you can never lay down any new memories. This is obviously completely disabling, and is incurable. To avoid this,
alcohol detoxification should always be under medical supervision, and with Thiamine given (via injections of some kind)
since it takes approx 6 weeks for digestive system to begin to re-absorb Thiamine properly - which is too late if you
are only taking Thiamine tablets!

A final comment - taking stimulants (speed, cocaine, etc) with Alcohol allows you to get more drunk and can stop
*some* of the 'drunk' effects (not all due to the fact that, as noted above, Alcohol is 'dirty' in that it has effects all
over the brain). Taking stimulants to drink more alcohol is a very dangerous thing to do though. You can easily become
lethally drunk, and then go to sleep... the stimulants wear off more quickly, and you end up going into a coma, and
(for example) inhaling your own vomit, or just stopping breathing. A friend of mine, who was a medical doctor, died
due to this - the stimulant was caffeine (about 20 cans of coca cola per day at least) and a single night of heavy drinking;
no other medications but he never woke up. He was about 25 at the time, and was just completing his second year working
as a doctor (was very caring, and very good in his medical care, especially emergency situations) :(
 
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