1. Has anyone, smokers and non-smokers alike taken oral nicotine via chewing gum?
I am interested for the people who have a tolerence what it did as well for the people that don't what it did.
2. As well Wikipedia says nicotine can trigger the beta-endorphins in higher doses. Does this ring true to anyone?
I know that if I smoke a pack a day I get gittery and anxious instead of opiated or anywhere near calm/relaxed. As for my tolerence I usually have anywhere from 0-5 smokes a day.
I will admit however that sheesha smoked properly in a hooka is pretty much a state of total relaxation. Sometimes I like it just as much as I would cannabis or hashish (esp that my tolerence for THC is way too high now).
The next best thing to sheesha is flavored pipe tobacco that comes in 50g and 42g pouches like Amphora, Borkum Riff, Capitan Black and others like that. Instead of using a pipe, usually I just roll them in papers and smoke it like that. I find the effects from that kind of tobacco very different as well, in that its more relaxing than normal tobacco but not as 'sedating' as sheesha. Not really stimulating but still uplifting.
I also find cigars (cubans) give a distinct feel/effect. Its hard to explain but theres nothing to compare it to. I find it just as harsh as regular tobacco and stronger than regular tobacco. I find that it makes me very creative, productive and dreamy but stimulated as well.
Regular cigarettes I just find to be motivating, outgoing and simulating to the point of 'rushy' type feeling. However I get a noticable uplifting/mood boost from a cigarette.
Wikipedia states:
"Pain is reduced by the increases of acetylcholine and beta-endorphin. Anxiety is reduced by the increase of beta-endorphin. Nicotine also increases sensitivity in brain reward systems.[26] Most cigarettes (in the smoke inhaled) contain 0.1 to 2.8 milligrams of nicotine.[27]
Research suggests that, when smokers wish to achieve a stimulating effect, they take short quick puffs, which produce a low level of blood nicotine.[28] This stimulates nerve transmission. When they wish to relax, they take deep puffs, which produce a high level of blood nicotine, which depresses the passage of nerve impulses, producing a mild sedative effect. At low doses, nicotine potently enhances the actions of norepinephrine and dopamine in the brain, causing a drug effect typical of those of psychostimulants. At higher doses, nicotine enhances the effect of serotonin and opiate activity, producing a calming, pain-killing effect. Nicotine is unique in comparison to most drugs, as its profile changes from stimulant to sedative/pain killer in increasing dosages and use."
I am interested for the people who have a tolerence what it did as well for the people that don't what it did.
2. As well Wikipedia says nicotine can trigger the beta-endorphins in higher doses. Does this ring true to anyone?
I know that if I smoke a pack a day I get gittery and anxious instead of opiated or anywhere near calm/relaxed. As for my tolerence I usually have anywhere from 0-5 smokes a day.
I will admit however that sheesha smoked properly in a hooka is pretty much a state of total relaxation. Sometimes I like it just as much as I would cannabis or hashish (esp that my tolerence for THC is way too high now).
The next best thing to sheesha is flavored pipe tobacco that comes in 50g and 42g pouches like Amphora, Borkum Riff, Capitan Black and others like that. Instead of using a pipe, usually I just roll them in papers and smoke it like that. I find the effects from that kind of tobacco very different as well, in that its more relaxing than normal tobacco but not as 'sedating' as sheesha. Not really stimulating but still uplifting.
I also find cigars (cubans) give a distinct feel/effect. Its hard to explain but theres nothing to compare it to. I find it just as harsh as regular tobacco and stronger than regular tobacco. I find that it makes me very creative, productive and dreamy but stimulated as well.
Regular cigarettes I just find to be motivating, outgoing and simulating to the point of 'rushy' type feeling. However I get a noticable uplifting/mood boost from a cigarette.
Wikipedia states:
"Pain is reduced by the increases of acetylcholine and beta-endorphin. Anxiety is reduced by the increase of beta-endorphin. Nicotine also increases sensitivity in brain reward systems.[26] Most cigarettes (in the smoke inhaled) contain 0.1 to 2.8 milligrams of nicotine.[27]
Research suggests that, when smokers wish to achieve a stimulating effect, they take short quick puffs, which produce a low level of blood nicotine.[28] This stimulates nerve transmission. When they wish to relax, they take deep puffs, which produce a high level of blood nicotine, which depresses the passage of nerve impulses, producing a mild sedative effect. At low doses, nicotine potently enhances the actions of norepinephrine and dopamine in the brain, causing a drug effect typical of those of psychostimulants. At higher doses, nicotine enhances the effect of serotonin and opiate activity, producing a calming, pain-killing effect. Nicotine is unique in comparison to most drugs, as its profile changes from stimulant to sedative/pain killer in increasing dosages and use."
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