I was very curios about this. I have a mixed understanding of it. I heard it's an nmda antagonist(nonselective?)which I assume means it can be dissociative at the right dose. It's a sigma agonist which means what?---absolutely nothing?? what are sigma agonists? and it's either a dopamine agonist or antagonist? My question is, at a high enough dose which should be(anyone know??) would this have atleast some semi-interesting dissociative effects. I've heard alot of people talk about it sucking alot in intended doses, but what about at much higher doses? Altho if it does blocks dopamine then it may be nasty stuff. It's chem structure is similar to other nmda antagonists like ifenprodil and similar chems.