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Great mental health results from MDMA

wirkdy

wirkdy

Bluelighter
Joined
Nov 29, 2021
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547
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Europe
I'd been experimenting with different substances to improve my mental health and fight a very long lasting depression and try to get active and see positive light again, I tried shrooms, weed/hash, ketamine but none of those gave me long lasting improvements untill I found out that also MDMA is used in mental health relief situations even though it is not talked about as much as shrooms or ketamine in that regards and it was also used in psychiatry before it got banned, so I got myself a few grams of this substance in crystals form.

I tried it for the first time last week and I got impressive results, truly life changing effects that cleaned my brain from depression, I know it's early to say it is definitive now but I'm optimistic.

I've been microdosing almost daily with doses of 5, 10, 15 maybe 20mgs, actual micro doses, during the peak I repeat by voice or in my mind short positive mantras like: light is positive, light is light, fill your mind with positive light / positive mind, mind full of positivity / active mind, your mind is active and phrases like that and I feel very good.

Any of you experienced the same?
Do you know anything about microdosing daily?
I reasearched but found no health hazards with mdma contrary to ket for example that hurts your body, do you know any negative effects mdma can have on your health?
 
wirkdy said:
I've been microdosing almost daily with doses of 5, 10, 15 maybe 20mgs, actual micro doses, during the peak I repeat by voice or in my mind short positive mantras like: light is positive, light is light, fill your mind with positive light / positive mind, mind full of positivity / active mind, your mind is active and phrases like that and I feel very good.
Click to expand...
Microdosing MDMA is a horrible idea.
I strongly urge you to stick to regular doses (80-120mg with no more than a 60-80mg redose) spaced apart by at least one month.
 
arrall said:
Microdosing MDMA is a horrible idea.
I strongly urge you to stick to regular doses (80-120mg with no more than a 60-80mg redose) spaced apart by at least one month.
Click to expand...
ok but why is it a horrible idea? I did my research about mdma but haven't found much about negative effects.
I also feel that 80-120 mg is a strong dose, not that I can't bare it but I got good effects with about 20mg so I don't really know. Also one month wait to take it again? way too long, I could wait one to two weeks maximum, at least now I'd like to try this dosage/time but I'm open to change and listen to any tips you guys give me....
 
I believe all medicines have what is termed a 'therapeutic window'. While it's quite complex in practice, it does basically mean that below a certain level, it produces no response. This is tested to a detailed level.

But in the case of MDMA, it's neurotoxicity seems to be most pronounced with chronic dosing, so it's NOT safer to do 20mg/day than 140mg/week.
It will not cause monoamine release or reuptake inhibition ad those doses.

For the purposes of psychotherapy, I feel sure that they would want to use the MINIMUM dose.

That said we don't know everything. We know that the placebo effect can be powerful but then we know every person is an individual.

So if it works for you, I cannot argue. Just be aware of the neurotoxicity.
 
Well - that works out less than you are taking. I don't think one needs the 125mg usually stated when it's to treat depression.

Why not sign up for an MDMA trial. They will appreciate your efforts.
 
100mgs might be a lot if you are only taking 20mgs for your microdosing. you say you were dosing daily and now want to take a week off, so you might want to try 20mg again because the week off will have you with a little less of a tolerance. don't let people pressure you to take more. taking more might just make you come down harder. the mantras could be leading you to get better results with less of a dose.

for me though, i have to say, i took half of a mda pill one time and it was great. i waited three weeks to take the other half and even after three weeks the tolerance made it so i experienced literally nothing but being sober... i went a couple more months and tried some mdma a few times and my tolerance was always just really high after my first trying mda... i think the mda pill i took was just stacked though and all of the other pills were just garbage. maybe you'll have better luck with your crystals though. good-luck

i'm thinking from my experiences, you might want to take more than a week between doses and just dose like a micro-dose of 20mgs.
 
I'm keen to know if microdosing will result in tolerance.

I just know that even in the 80s we had all read the 'not more than 1.5mg/Kg not more often than every 6 weeks'. Shulgin is quite the expect.

I suspect that 6 APB might be more suided to microdosing. After all, it's got a 2017 patent and so a LOT of research was carried out.
 
pubmed.ncbi.nlm.nih.gov

Neurotoxicity of ecstasy (MDMA): an overview - PubMed

"Ecstasy" (MDMA) is a powerful hallucinogenic drug which has raised concern worldwide because of its high abuse liability. A plethora of studies have demonstrated that MDMA has the potential to induce neurotoxicity both in human and laboratory animals. Although research on MDMA has been carried...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Just Google. It isn't a secret. I'm not sure if it's MDMA or a metabolite. But that is why someone patented 6 APB (and relatives) i.e. it demonstrates less neurotoxici.
 
wirkdy said:
I'd been experimenting with different substances to improve my mental health and fight a very long lasting depression and try to get active and see positive light again, I tried shrooms, weed/hash, ketamine but none of those gave me long lasting improvements untill I found out that also MDMA is used in mental health relief situations even though it is not talked about as much as shrooms or ketamine in that regards and it was also used in psychiatry before it got banned, so I got myself a few grams of this substance in crystals form.

I tried it for the first time last week and I got impressive results, truly life changing effects that cleaned my brain from depression, I know it's early to say it is definitive now but I'm optimistic.

I've been microdosing almost daily with doses of 5, 10, 15 maybe 20mgs, actual micro doses, during the peak I repeat by voice or in my mind short positive mantras like: light is positive, light is light, fill your mind with positive light / positive mind, mind full of positivity / active mind, your mind is active and phrases like that and I feel very good.

Any of you experienced the same?
Do you know anything about microdosing daily?
I reasearched but found no health hazards with mdma contrary to ket for example that hurts your body, do you know any negative effects mdma can have on your health?
Click to expand...
I’m definitely no expert on the existing research on MDMA and therapy however, I thought that MDMA was shown to be effective during talk-therapy sessions while the patient had dosed MDMA.
Since MDMA removes much inhibition, self-consciousness, perhaps shame, one could finally understand the nature of ones suffering so as to be able to make real positive changes to what were previously unhealthy habits or methods of thinking.
Also the empathic aspect of connecting with another person during a healthy and sincere conversation heals in that it is the opposite of the detachment that comes from a faster and high-tech world we are often forced to live.
 
Well I post what I find. I WILL bore you with stupid references, but YOU get what I get. That is my BL role (I think). The bloke who DID go through the education system and applies that education in the form of reference... lost of reference.

That is how science works. I will never tell you a drug is SAFE, I will only provide LD50 and references plus references of fatalities when people mixed multiple drugs. It's just impossible to say a mixture is safe....
 
wirkdy said:
I'll take a break of few days and try a bigger dose of about 100mg weekly
Click to expand...

Not more than 1.5mg/Kg body-weight not more often than once every 6 weeks. Shulgins's Law.

Don't forget, the guy was a medicinal chemist so he really KNEW. 6APB MAY be safer... but do not rely on that.
 
Microdosing MDMA might not put you at much risk for neurotoxicity (although why even chance it..) when we look at “MDMA preconditioning” research. But it’s just not effective when you compare to what can be obtained from a good solid 120mg dose once every few months.

-GC
 
ibb.co

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Image 1 hosted in ImgBB
ibb.co ibb.co

Now, consider why I chose to put the S & O in their respective places and chose the primary and not the secondary amine. You might need to use ChemSpider, PubCHem and PiHKAL to see why those choices were made.

Also, what will the metabolic products be?

People like designing stuff, few seem to care how the body will deal with them.

Like 4MMC - the p-Me would make it am MAOI but the beta-ketone means it's not an MAO ligand.... the methylanine was chosen because it will directly add to a secondary -Br in a facile manner. It's solubility characteristics makes the product easy to isolate AND the p-Me is ALSO a sacficicial moiety. Over 90% of 4MMC undergoes hydroxylation and then further oxidation of that 4-methyl.... so it's metabolism is easy to guess and easy to check.

BTW it was a Russian guy in Hyperlab who first mafe 4MMC simply because he only had the precursors (and pre-precursors) for that SPECIFIC compound. I've met dozens of people who claimed to have invented it... and it's even in an early patent but the first person to recognize it as a club drug is an unnamed Russian.
 
It was almost assuredly real then. Try 120 mg next time! Or maybe just 100 mg. I rolled about 2 to 3 hundred times until mdma quit working for me, but that was 20 years ago.
 
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