Fioricet Extract ?

[Wonderbread]

I'm looking at a small pile of Fioricet. I'm thinking they'd be nicer minus the caffeine and acetominophen.
Does anyone know how the solubility of this would be in different solutions?
Inactive Ingredients: crospovidone, FD&C Blue #1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid.
Butalbital: (5-allyl-5-isobutylbarbituric acid), is a short to intermediate-acting barbiturate. It has the following molecular formula: C11H16N2O3 with molecular weight 224.26.
Acetaminophen: (4’-hydroxyacetanilide), is a non- opiate, non-salicylate analgesic and antipyretic. It has the following molecular formula: C8H9NO2 with molecular weight 151.16.
Caffeine: (1 ,3,7- trimethylxanthine), is a central nervous system stimulant. It has the following molecular formula: C8H10N4O2 with molecular weight 194.19.
Would the molecular weight affect solubility in water? I'm pretty sure the aspirin wouldn't be rough to take out, but the caffeine is where I'm looking.
Anyone know how delicate the chemical structure of butalbital is? I.E. anything other than varied temperatures of distilled water, would that change the chemical structure?
Thank yas, I know its an easy one

 

[Grand Master of Somniferon]

Originally posted by Wonderbread:

Caffeine: (1 ,3,7- trimethylxanthine), is a central nervous system stimulant. It has the following molecular formula: C8H10N4O2 with molecular weight 194.19.
Thank yas, I know its an easy one
I know that caffeine is readily dissolved in water, as the coldwaterworld page says, or at least one of those extraction pages.

 

[fairnymph]

I actually LIKE the butalbital/caffeine combo...I think it works nicely. Maybe I'm just weird though...and it is true that acetaminophen is the crap filler of the universe.

 

[ZiZaRollin]

Fiorcet w/Codine is definitely my rx drug of choice. The caffeine is definitely a good kicker for the buzz. I tend to enjoy taking it with a cup of coffee additionally for a real good kick!
I really wish this were more readily available on the street

 

[zorn]

I installed the Merck index just for you, so you'd better be grateful.
Caffeine :
One gram dissolves in 46 ml water, 5.5 ml water at 80degrees, 1.5 ml boiling water, 66 ml alcohol, 22 ml alcohol at 60degrees, 50 ml acetone, 5.5 ml chloroform, 530 ml ether, 100 ml benzene, 22 ml boiling benz ene. Freely sol in pyrrole; in tetrahydrofuran contg about 4% water; also sol in ethyl acetate; slightly in petr ether. Soly in water is increased by alkali benzoates, cinna mates, citrates or salicylates.
Acetaminophen:
Very slightly sol in cold water, considerably more sol in hot water. Sol in methanol, ethanol, dimethylformamide, ethylene dichloride, acetone, ethyl acetate. Slightly sol in ether. Practically insol in petr ether, pentane, benzene.
Butalbital:
Practically insol in water and petr ether. Sol in alcohol, chloroform, ether, acetone, glacial acetic acid, also in solns of fixed alkali hydr oxides
So it looks like you could could do a fairly effective extraction with ether. Or you could dissolve the tablets into hot water, discard the solution, and keep the filtrate.

 

[Wonderbread]

I appreciatte the advice I'll play Iron chef tonight and see what comes out.
Thank you, I need to buy me a Merck index

 

[empathic acid demon]

Not worth the effort for a weak barb, but good luck.