^ The ampkines do sound interesting....
Yeah I was never foolhardy enough to push my dose over a gram because of fears of physical damage. Less of a worry with MXE, much less with K but I can never find K that's trustworthy and isn't nosebleed expensive.
I can't find anyone who's ever heard of K in my area, let alone someone selling it, but PCP and DXM practically grow on trees around here, hehe. Shame, as K's one of the main drugs I'd like to try, and practically the only one in that list that's entirely unobtainable at the moment.
On 1.2 grams of DXM and 90mg Diphenhydramine recently, I was sucked into an alternate reality entirely convinced I was in the "true" reality. Immediately upon closing my eyes, I was in another world, yet I was walking through my own house. Turns out, a nice black couple decided to "occupy" one of my empty rooms. Most people would freak out in this type of situation, but I personally found it hilarious and was cool with them staying here for a bit. Strangely enough, I was perfectly coherent and sober in this dream. Upon opening my eyes, I shouted in complete ecstasy, "Oh my god!" That was my second craziest experience with psychedelics, and in going back to DXM, I came to realize just how powerful a drug it really is. If I'm honest, I far prefer it to MXE, despite being the riskier of the two. A bit off-topic, but nonetheless, these types of experiences are exactly why I spent so much time trying to find ways to reduce tolerance to dissociatives, and though it's not perfect, this is the closest, and only, solution I've found yet.
Edit: I recently discovered this Wikipedia entry here:
http://en.wikipedia.org/wiki/Ditolylguanidine
In it, it mentions this substance had potentiated NMDA antagonists. Looks like sigma agonism could be another suitable route for potentiation aside from marijuana. Obviously most dissociatives are sigma agonists, all of which would certainly *not* be a good idea to use in tandem with another dissociative. I was thinking more along the lines of PRE-084, which surprisingly is obtainable. The amount of common substances that exert their effects through sigma agonism is fairly shocking, after doing a bit of research. Methamphetamine, opiates, most dissociatives, DMT, DHEA, escitalopram...the list goes on.
Furthermore, I'd imagine using a sigma antagonist in combination with AMPAkines over a period of time would be even more effective in resetting tolerance than with AMPAkines alone. AC927 is about the only one that looks selective enough to be suitable for this task. All others display various other actions that would be counter-productive to daily functioning. BL group buy, anyone?
Another edit: just a speculative thought, but I wonder if, considering AMPAkines can stall and even possibly reverse dissociative tolerance, dissociatives can do the same for AMPAkines once a tolerance is achieved. I know of no one ever experiencing tolerance with a racetam/raceram or any other AMPAkine with the exception of Phenylpiracetam, which likely only causes tolerance to the stimulant effect anyways. If AMPAkines take this long to gain tolerance, or even don't gain tolerance at all, this makes them an even more desirable choice to long-time dissociative users looking to reverse their tolerance. Again, while it may take awhile to reverse tolerance to any worthwhile extent, it's currently the only known option out there for this purpose, only if used in combination with abstinence. If this is not done, the AMPAkines will do nothing more than stall tolerance, significantly weaken the effects of dissociatives if used in combination, and ultimately prove a massive waste of money. Abstinence is key, but abstinence alone won't do much to reverse tolerance. Abstinence + Strong AMPAkines, on the other hand, should reverse tolerance after being used for a long period of time, 6 months at the very least, ideally 8 months to a year. Methylene Blue has been said to reverse tolerance as well, but I can't attest to this, and certainly not when speaking of dissociatives. Along with that, I'm not sure if tolerance reversal is permanent or if it only lasts until Methylene Blue wears off, or in this case, if there is any effect on tolerance at all. It's a long shot, but it's incredibly cheap, so why not give it a shot as well? Under $20 for the solution and dropper bottle, a supply which will last multiple decades easily, so long as it's dosed at the proper 60mcg, which seems to work best for most, myself included.