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DXM slows opioid tolerance development

AbraMontague

Bluelighter
Joined
Dec 31, 2000
Messages
1,006
Check this out. http://www.drugsandthings.com/Pain_Management.html
Under morphine ER it says this:
"Morphine SO4 E.R. with Dextromethorphan: 15, 30, 60, 90, 100, 160, or 200 mg : Morphine is, of course, the primary drug in the area of pain management. As an analgesic preparation it is virtually irreplaceable. Unfortunately, when given chronically, tolerance always ensues. This is why we have incorporated Dextromethorphan into the formulation. Recently, it has been shown that Dextromethorphan can slow the development of morphine tolerance. It does this by binding to and blocking the NMDA receptor. This is the receptor that is needed for morphine tolerance to develop. The E.R. stands for extended release."
Just sounded interesting.
 
Yup.. it's a good time to be a junkie, as we can keep the tollerance under control with some Robotussin, then kill that withdrawal with some Immodium..
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PAK CHOOIE UNF! Do not trust the pusher robot, he is malfunctioning, we are here to protect you..
 
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