• N&PD Moderators: Skorpio | thegreenhand

Rectify's molecular poetry thread

1-(3,4-dimethylphenyl)-2-methylaminopropane.png


ROUGH_RIDER
1-(3,4-dimethylphenyl)-2-methylaminopropane

Another horny molecule. Kin to the discontinued Xylopropamine.
 
(2S,5R,6R)-2-carbomethoxy-6-(2-(3,4-dichlorophenyl)-1-methylethyl-amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane.png


SNIFFLESS
(2S,5R,6R)-2-carbomethoxy-6-(2-(3,4-dichlorophenyl)-1-methylethyl-amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane

An Antibiotic With Bite.
 
Many Of These Drugs Have Been Made And Tested On Me. I Like Taking New Drugs, Especially Ones I Have Posted.

1-(3,4,5-trichlorophenyl)-2-methylaminopropane.png


SUPERFREAK OR IS IT JUST ANOTHER JIM?
1-(3,4,5-trichlorophenyl)-2-methylaminopropane
 
1-allyl-3-methoxy-4-hydroxybenzene.png


EUGENOL
1-allyl-3-methoxy-4-hydroxybenzene

excess HBr(g)

1-(3,4-dihydroxyphenyl)-2-bromopropane.png


1-(3,4-dihydroxyphenyl)-2-bromopropane

CH2Cl2, KOH

1-(3,4-methylenedioxyphenyl)-2-bromopropane.png


1-(3,4-methylenedioxyphenyl)-2-bromopropane

CH3NH2(g), THF

1-(3,4-methylenedioxyphenyl)-2-methylaminopropane.png


ECSTASY
1-(3,4-methylenedioxyphenyl)-2-methylaminopropane

3 Steps.
 
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1-(2,6-dimethoxypyridine-4-yl)-2-aminopropane.png


CARLITO
1-(2,6-dimethoxypyridine-4-yl)-2-aminopropane

from

4-aza-3,5-dimethoxybenzaldehyde.png


4-aza-3,5-dimethoxybenzaldehyde
 
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1-(pyridine-4-yl)-2-ethylaminopropane.png


DJ SAMMY "THAT GIRL'" AGUILERA
1-(pyridine-4-yl)-2-ethylaminopropane

1-(pyridine-4-yl)-2-methylaminopropane.png


MARK
1-(pyridine-4-yl)-2-methylaminopropane

1-(pyridine-4-yl)-2-aminopropane.png


JUNIOR
1-(pyridine-4-yl)-2-aminopropane

from the oxidation of

4-methylpyridine.png


4-methylpyridine, a natural product
 
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(2S)-1-methyl-2-(pyridine-4-yl)-pyrrolidine.png


LAFFY_TAFFY_TOBAKKY (isonicotine)
(2S)-1-methyl-2-(pyridine-4-yl)-pyrrolidine
 
The following 3 compounds were inspired by Nucenta.

N,N-dimethyl-1-amino-3-phenyl-2-(2S)-methylpropane.png


ANALGEAZYSIACKER
N,N-dimethyl-1-amino-3-phenyl-2-(2S)-methylpropane

possible pain killer

Hypothetical Synthetic Outline:

KCN + 1-phenyl-2-bromo-propane, then
reduce triple bond to the primary amine with NaBH4 in alcohol and N,N-dimethylate that product with 2 molar equivalents of formaldehyde and NaBH3CN in MeOH @ pH of 7.

N,N-diethyl-1-amino-3-phenyl-2-(2R)-methyl-3-oxopropane.png


SLACKER_CRACKER
N,N-diethyl-1-amino-3-phenyl-2-(2R)-methyl-3-oxopropane

From 1-phenyl-1-oxo-2-bromo-propane. That oxo would prolly need protecting then deprotecting with something like ethylene glycol. Substitution of 2 equivalents of formaldehyde with acetaldehyde yields this latter N,N-diethyl compound.

SLACKER_CRACKER is then the precursor for

N,N-diethyl-1-amino-3-carbomethoxy-3-phenyl-2-(2S)-methyl-propane.png


FANCY_NANCY
N,N-diethyl-1-amino-3-carbomethoxy-3-phenyl-2-(2S)-methyl-propane

using the Anderson benzylic-OH to carbomethoxy functional group named rxn.
 
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1-(2-phenyl-1-methylethyl)-2-(4-azabenzoyl)-hydrazine.png


GREAT_EXPECTATIONS
1-(2-phenyl-1-methylethyl)-2-(4-azabenzoyl)-hydrazine

Keywords: Amphetamine, isoniazid (INH), iproniazid, phenelzine.

This bad boy has everything going for it. It might help treat adhd, depression, and tuberculosis. Or it might make one drop dead. I doubt that, though.

INH + 1-phenyl-2-halo-propane --> Wallah (viola)! Something Like That. The halogen used could be chloro, bromo, or iodo.

You Have To Want To Believe To Believe.

Yours Truly,
Pip
 
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1-phenyl-1-carbomethoxy-2-methylaminopropane.png


BOUNCE
1-phenyl-1-carbomethoxy-2-methylaminopropane

This substance is SO GOOD. I wish I had some again. Just treat it with respect and don't try to stay high on it 24/7 or I would imagine you'll be taking a trip down the rabbit hole down to la la land.
 
1-(2,4,6-trimethylphenyl)-2-aminopropane.png


EXPLODING_IN_A_MIND_SOMEWHERE
1-(2,4,6-trimethylphenyl)-2-aminopropane

1-(2,4,5-trimethylphenyl)-2-aminopropane.png


DOING_SOMETHING_ON_a_D.A.R.E
1-(2,4,5-trimethylphenyl)-2-aminopropane

Subtle, But Rich. Rico Suave!
 
1,7,7-Trimethylbicyclo%5b2.2.1%5dheptan-2-one.png


CAMPHOR
1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Br2

3-bromo-1,7,7-Trimethylbicyclo%5b2.2.1%5dheptan-2-one.png


3-bromo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Benzene (or 1,3-benzodioxole), FeBr3

3-phenyl-1,7,7-trimethylbicyclo%5b2.2.1%5dheptan-2-one.png


3-phenyl-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Reductive Amination

2-methylamino-3-phenyl-1,7,7-trimethylbicyclo[2.2.1]heptane.png


HAPPY_CAMPHOR
2-methylamino-3-phenyl-1,7,7-trimethylbicyclo[2.2.1]heptane

2-methylamino-3-(3,4-methylenedioxyphenyl)-1,7,7-trimethylbicyclo%5b2.2.1%5dheptane.png


MADONNA
2-methylamino-3-(3,4-methylenedioxyphenyl)-1,7,7-trimethylbicyclo[2.2.1]heptane

Of Course, I Still Love ❤ Madonna!

2-methylamino-3-carbomethoxy-1,7,7-trimethylbicyclo%5b2.2.1%5dheptane.png


SNUFFY_SMITH
2-methylamino-3-carbomethoxy-1,7,7-trimethylbicyclo[2.2.1]heptane

Camphor
3-bromocamphor
3-cyano-camphor
3-carboxy-camphor
3-carboxy-2-methylamino-camphor
3-carbomethoxy-2-methylamino-camphor aka SNUFFY_SMITH
 
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Adding an N,alpha-methyl would, in almost all likelihood, improve LPH-5's activity.

(S)-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-methyl-piperidine.png


N,alpha-methyl-LPH-5
(S)-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-methyl-piperidine
 
3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine.png


THORAZINE: An Underutilized Classical Antipsychotic
3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
 
8-chloro-11-(3-(4-methylpiperazinyl)propyl)-(benzo%5bb%5d%5b1,4%5dbenzothiazepine).png


KRAZYQUELL
8-chloro-11-(3-(4-methylpiperazinyl)propyl)-(benzo[1,4]benzothiazepine)

Improved Thorazine / Seroquel.
 
Like 99% sure samidorphan is an opioid antagonist that is supposed to prevent weight gain from olanzapine. It won't cause opioid withdrawal....Definitely probably will cause anhedonia

Looked like a dumb drug when I saw it come out. Glad your off it OP
 
No, I've never tasted that one, but I would in the name of science if given the opportunity.

2-(dimethylamino)propyl-4-aminobenzoate.png


NEO_NOVOCAINE
2-(dimethylamino)propyl-4-aminobenzoate

2-(dimethylamino)propyl-3,4-methylenedioxybenzoate.png


DESIGNER_NOVOCAINE
2-(dimethylamino)propyl-3,4-methylenedioxybenzoate

I'm Not Kidding.
 
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CH3-O-CH3

HUFFMAN
dimethyl ether

Safe for use as a general anesthetic? I don't know. I would imagine so.

CF3-O-CF3

EVEN_STRONGER
bis-(trifluoromethyl)-ether
 
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