Opioids Does Taking (Oral) Opioids on a Full Stomach Make Them Less Effective?

[ChemicallyEnhanced]

Had a lot to eat so don't wanna waste them :/
Does it make them less effective/less noticeable, or will it just take longer to feel the effects?

 

[burn out]

Of course it does. It will take longer to feel the effects but the effects won't ever reach as high. It is a bit like an extended release mechanism so if you want a somewhat longer but significantly milder effect than taking them on a full stomach might actually be a good idea.

 

[Jnowhere]

Absolutely, worse with benzos though

 

[PtahTek]

May not be less effective but will last longer. I mean you may not feel the comeup but if taken for pain it will have a longer effect. Just my experience with opioids in general.
Ymmv

 

[Jen X]

I don't notice any difference. If you're full may take longer to kick in but it will still be absorbed