Dre1990
Bluelighter
I wanna know if Clonidine pills help potentiate morphine and other opioids. Does anyone do it?
It does potentiate benzos apparently
It does potentiate benzos apparently
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BDD Moderators: Keif’ Richards | negrogesic
Opioids Does clonidine potentiate morphine?
- Thread starter Dre1990
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Bluelighter
It does not whatsoever. I also would not say it potentates anything other than the sedative effects of benzos.
Potentiation in the way that we use the term around here means something specific. Usually, we are talking about using one substance concurrently with another in such a way that the former substance interacts in such a way as to actually boost the potency/effects of the latter.
Using Cocaine together with Alcohol creates a third, separate substance in the body known as Cocaethylenene which is more potent a substance than the other two. It would be appropriate to say that Alcohol potentiates Cocaine and vice versa.
Cannabis will not potentiate Alcohol. Both substances have sedative effects that can lead to greater perceived levels of intoxication. However, you're just experiencing Cannabis and Alcohol simultaneously. They do not happen to interact with each other in this symbiotic way described above.
Likewise, Clonidine is not going to potentiate Morphine. Clonidine is known to lower blood pressure and to a lesser extent, pulse. These effects typically lead to relaxation/sedation. If you take Clonidine with Morphine, you'll be more likely to become sedated, but it's not actually going to make the Morphine "better" or stronger in any way. The combination is not going to lead to a greater relief from withdrawal, for instance.
Using Cocaine together with Alcohol creates a third, separate substance in the body known as Cocaethylenene which is more potent a substance than the other two. It would be appropriate to say that Alcohol potentiates Cocaine and vice versa.
Cannabis will not potentiate Alcohol. Both substances have sedative effects that can lead to greater perceived levels of intoxication. However, you're just experiencing Cannabis and Alcohol simultaneously. They do not happen to interact with each other in this symbiotic way described above.
Likewise, Clonidine is not going to potentiate Morphine. Clonidine is known to lower blood pressure and to a lesser extent, pulse. These effects typically lead to relaxation/sedation. If you take Clonidine with Morphine, you'll be more likely to become sedated, but it's not actually going to make the Morphine "better" or stronger in any way. The combination is not going to lead to a greater relief from withdrawal, for instance.