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Does all the substances have d- and l- isomers?

Survival0200

Survival0200

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Does all the substances have d- and l- isomers? Dextro- and levo- if I've understood correctly.

BTW is that dextro- written with a capital d; like D- and l- isomers -- Dextro- and levo- isomers? Or does it matter?

Anyway, I know at least amphetamine has both of these isomers, but how about e.g. diazepam? Is it possible to make dextro-diazepam or levo-diazepam (<- would that be levo-diazepam or levodiazepam?)?

How does these isomer things work? :)
 
Your best bet is to scroll down in this thread and read phase_dancers comments.

Note that diazepam doesn't have a chiral carbon, i.e the mirror images of the molecule would be superimposable over each other. Thus no optical isomers.

Diazepam.jpg


As for the little d, big D, R, S, etc. stuff...as long as you're clear in the intention of what your saying and it's easily understood, it doesn't matter to me. Can anyone tell me what the symmetry goup of diazepam is?
 
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If your right handed, think of dextro as your right hand, levo your left. Dex is usually more active.
 
oldkaw said:
If your right handed, think of dextro as your right hand, levo your left. Dex is usually more active.
Click to expand...

Not at all, that's just from reading about stimulants... the dextro isomer of morphinans isn't active as an opiate at all. The most active isomer depends upon the receptor in question
 
Isomer just means different atomic configuration. l,d and others are ways for a person to tell witch configuration you are talking about.
 
Why is it that d- and l- are still so much in use? It seems to me that the only thing they're good for is carbohydrate chemistry -- anything you can draw a fisher projection of; but other than that, the designations seem pretty useless. Why not just use R and S? That actually says something about the compound.
 
D and L says something about the compound, just something different. Who really cares. When it comes to pharmacology, either one is active, or it isn't. You can call one Bob and one John for all I care.
 
The full name of stereoisomers show R and S orientations and whether its (+) or (-). From memory, d- is same as (+); l- is same as (-).

Bit of trivia.
 
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