Help! Dmx trip dosage

[Dampflownder]

I am new to dmx and want to try the trip ive heard of the plateaus and the different stages i want to do a stage 3 but i dont know how to dose myself which brand of dmx hbr should i use and how many ml should i take of that brand for a stage three

 

[arrall]

This should help you out: https://dxm.tripsit.me/
Find a brand where the only active ingredient listed on the bottle is Dextromethorphan HBr.
No Acetaminophen/Paracetamol/APAP, no guaifenesin, no diphenhydramine, and definitely no pseudoephedrine.

 

[cripkeeper]

If your new to dxm it'd be wise to start lower. It's been a long time, but my experience with dxm is that the same dose won't take me to the same place twice. It hits different every time.
And lower plateaus can be surprising intense.0

 

[Chris Timothy]

I don't like that tool. There are so many more variables involved than body weight. There's a reason that ratio gets ignored in general clinical practice. I've seen a Google Talk on it, and it gets into mathematical power laws concerning the surface area of the liver. Best is to stick with individual starting-low-working-up probing and not falling for any security illusions of online tools, if you want my two cents.

 

[Snafu in the Void]

Just need to say it's also very important you aren't taking any medications such as antidepressants

 

[plumbus-nine]

Yeah, that DXM (dextromethorphan) dose calculator fooled me and others into assuming that one would need to go to higher plateaus to enjoy the full potential of the drug and that its dosage wasn't so individually relevant which both proved wrong. I loved DXM in dosages of 75-150mg, max. 300mg for compatibility with everyday life and 450mg at home. Anything higher would give me panic attacks from the potent norepinephrine component this drug has.

I'd recommend starting with 150mg and seeing where it brings you. You can always redose but once in your system you have to ride it out.
Also do higher dosages induce faster and stronger tolerance which in turn stops the low dosages from being pleasurable which again pleads for starting low.
DXM together with serotonergic antidepressants (almost all besides tianeptine) is strongly contraindicated, it can and will induce serotonin syndrome. Not equally strong in everybody, but when you find out it might be too late.

 

[Dampflownder]

I will definitely start at a lower plateau and i do not take anti depressants

 

[PriestTheyCalledHim]

Start lower, and take a dose to test allergies or if you do not have the enzyme or genetics, some people lack these and their body does not process DXM and they die or need to go to hospital.

Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs

Cytochrome P450 CYP2D6 is the most extensively characterized polymorphic drug-metabolizing enzyme. A deficiency of the CYP2D6 enzyme is inherited as an autosomal recessive trait; these subjects (7% of Caucasians, about 1% of Orientals) are classified ...

www.ncbi.nlm.nih.gov

Life-Threatening Dextromethorphan Intoxication Associated with Interaction with Amitriptyline in a Poor CYP2D6 Metabolizer: A Single Case Re-Exposure Study

We report a case of life-threatening intoxication and a controlled re-exposure study to dextromethorphan. A 60-year-old man developed postsurgical neu…

www.sciencedirect.com

 

[izo]

Best effects when dosing around 300mg and after an hour 240-270mg again.