• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Misc Cyclizine now OTC in US?

Status
Not open for further replies.
S

SleeplessNights

Greenlighter
Joined
Jul 9, 2010
Messages
5
Location
Southeast US
I recently ran across some stories regarding the wonders of cyclizine and got interested. Apparently, it's now OTC in the US, and is the active ingredient in the children's preparation of one of the most popular motion sickness drugs on the market--which I confirmed in several places, not just wikipedia. However, I have not been able to find this children's preparation or any other name-brand, store-brand, or generic drug containing cyclizine anywhere, and I've looked in more than a dozen pharmacies over the past couple of weeks.

So, I've begun to wonder if, despite its current legal status, most pharmarmacies aren't carrying cyclizine simply because of the reputation that it managed to develop when it was on the shelves years back? I know I can order it off the internet, but I am almost as curious about the elusiveness of cyclizine as I am about cyclizine now.

Has anyone in the US seen this on pharmacy shelves? Or perhaps been able to buy it, but had to ask for it like you have to with Sudafed most places?

Thanks,
SleeplessNights
 
Last edited:
bonine for kids is apparently cyclizine... strange seeing as normal adult bonine is meclizine which is the same as Rx Antivert.

how does cyclizine compare to diphenhydramine for insomnia? i assume you're using it for potentiation?
 
QuasiStoned said:
I'm not aware of the reputation of cyclizine... is it supposed to be a good opiate potentiator or something?
Click to expand...

Yeah, apparently cyclizine was OTC in the UK for many years but is now either behind the counter or prescription-only...not sure. Anyway, they pulled it off the shelves because opiate users were prepping the pills and shooting them. Apparently, about 50mg of cyclizine will induce a heroin-like rush if iv'd with opiates already in the system, and is especially potent with methadone...and now it's otc in the US, but rarely stocked if my searches are any indication.

SN
 
Don't know if it's any good with sub, but maybe run a search for it? Ever hear of Diconal? One of it's two ingredients with cyclizine, and it was supposed to have the strongest rush of any opiate that's ever been produced...or so those few who were ?lucky? enough to experience it say. Too bad the pills had to be heated intensely to be shot, contained silicon, and basically turned into sand once they cooled down in your veins, but that was only the binders! The active ingredients worked wonders I hear.
 
cyclizine is an amazing chemical. nothing potentiates opiates better than this shit. the rush alone from it is good. mixed with opiates its fucking amazing. diconal produced the craziest rush ever. im sure this would be good to mix with subs. better than fucking benadryl. bonine pediatric you say? lemme check it out.
 
yeah, i would really like to try this with my suboxone iv dose. holy shit, this seems too good to be true. why do i have the feeling that its going to be impossible to find?
 
You can order it online. I wont post sites, but you can easily find things on google. I've seen it in one pharmacy, but it was in the back room and I had to ask for it.
 
Yeah, apparently cyclizine was OTC in the UK for many years but is now either behind the counter or prescription-only...not sure. Anyway, they pulled it off the shelves because opiate users were prepping the pills and shooting them. Apparently, about 50mg of cyclizine will induce a heroin-like rush if iv'd with opiates already in the system, and is especially potent with methadone...and now it's otc in the US, but rarely stocked if my searches are any indication.

Yes, that's absolutely correct. Back in the late 90's loads of hardcore addicts round my neck of the woods were banging cyclizine (Valoid tablets - 50mg cyclizine hydrochloride) with their methadone tablets (Physeptone - you can't get these any more, you can only get the juice these days) to reproduce the Diconol rush. I never tried it myself but the rush was supposed to be intense, but it also made users pretty psychotic and do absolutely crazy things without knowing it. One guy I know was found standing in a telephone box naked except for a tie and a briefcase pulling on his cock and having a telephone conversation with nobody. However, there was plenty of fallout from the usual dangers associated with IVing tablets, plus not knowing what they were doing all the time - plenty of people suffered horrible abcesses and some limbs were lost etc. Cyclizine was quickly taken off the shelves but there was one pharmacy in Northwich run by a poor old guy who was regularly bullied by the local scumbags to sell them Valoids. He was soon removed from his position. So be careful if you start messing with this shit. From what I can gather it is particularly effective with methadone - less so with heroin (different receptors affected and stuff).
 
Anybody having any luck?

Okay, so I ordered a box of Marezine and a box of Bonine for Kids off the internet...hopefully one of them will be filterable. If not, I suppose I'll just be eating them.

I gave up on buying cyclizine in person. Not a single one of the pharmacies in my area carry the stuff. They all have Bonine, but Bonine for Kids is not carried by any of them. And they don't have it behind the counter either.

I would say that the pharmacists around here were clued in, but opiate use in my area is pretty low, and IV users are almost nonexistent, I guess because heroin isn't available around here. Hell, my methadone counselor told me that less than 5% of the clinic's clients admitted to any IV use ever, and less than 1% used it as their primary ROA. So, I guess cyclizine may be doomed to be rare, since it's been OTC for over a year now and doesn't seem to be common...which is odd considering that it's the only motion sickness drug not contraindicated for children under 2. *sigh*
 
Cyclizine has always been OTC, it's just notoriously hard to find in its original or preferred form, the brand name "Marezine" tablets. "Bonine" for kids is Cyclizine, though they are only available in awful tasting chewable 25mg wafers. They are kind of big, but could probably be swallowed whole.

Cyclizine is one of the best Antihistamine Opioid potentiators, IME/O. Just sucks that Marezine tabs are so rare, and that most pharmacies do not stock them. I once tracked some down, but if I remember correctly, they were something like a dollar per pill, which is ludicrous.
 
Cyclizine under the brand name "Marezine" comes in 12 packs of 50mg tablets and can be found in all Long's Drugs/CVS Pharmacy in my area. Lucky me I guess:P

It ain't cheap though. 12 pills for just under $9.00 is ridiculous if you plan on IV'ing these with your methadone on a regular basis. Common ratio is one tablet cyclizine per 10mg methadone tablet. If doing a 40-50mg+ methadone shot, IME 3 tabs is enough. Any more than 3 at a time is a waste as it doesn't help that much more with potentiating the 'done. And yes, the rush from mixing the two IV as QUITE nice to say the least. Definitely recommended.

Even for those who take their dose orally, take your methadone first, then after about 20 minutes, take your cyclizine based on the ratio I wrote above. Of course you won't get any kind of "rush", but the overall pleasant feeling will still be there.

Oh and it works as a great potentiator for ALL opiates/opioids, just not as well when mixed with methadone IMO. So it can really be beneficial if you're a responsible user, as you will need LESS drugs to achieve the same/better effects.

There is a downside however, (yeah yeah, you can't have just ALL positive effects and no negative effects right?) This stuff is more expensive than the methadone itself (assuming you have legit 'script. It also seems to shorten the length of time the opiate/opioid lasts but not too much. From research the effect is physical, but I believe it to be slightly psychological as well. Excessive use of cyclizine can lead to addiction and cravings (though it isn't that bad and I was doing upwards of 15-20 pills a day at my peak and quitting cold turkey causes slight tachycardia and cravings.) The worst part is that after you've experienced its rush/effects, taking your methadone just by itself won't ever feel the same again, which will only lead to one thing: using MORE methadone in the hopes of reaching that same high, thus only increasing your tolerance.

Another good potentiator is hydroxyzine. It's Rx-only but it's unscheduled and I'll be damned if any doctor won't prescribe you an anti-histamine. <--this is for those having a hard time locating cyclizine.

**NOTE: Don't even THINK about shooting "Bonine for Kids" cyclizine. Those pills are HUGE and contains all kinds of junk, and I'm not just talking about the coloring or flavoring. Plus they only contain 25mg. So if you must inject, order the correct pills online.
 
Last edited:
^thanks for adding this info

ROXI- assuming you're in the US, Dramamine II contains meclizine, same as the bonine kelvane just tried.

They are pretty similar, but from what I hear, cyclizine is more desirable for potentiation purposes.

EDIT for kel's edit:

Unless they are labeled "meant for sublingual use" or something, I'd assume they are still meant to be taken orally. They might work sublingually, but I can't attest to that.

I've seen other OTC's meant to be taken sublingually and they were clearly labeled as such on the package and in the directions
 
Status
Not open for further replies.
Top