PetSMiLE
Bluelighter
Hello, I am not sure exactly where this thread belongs but it is more concerned with psychedelics than any single drug...
Most people are aware of a notable tolerance formed to most serotogenic drugs with consecutive days' usage. It is well documented that with nearly all psychedelics that this tolerance prevents the user from experiencing the same level of effects from identical doses used the previous night... whether it be LSD, psylocybin, etc. most of them do (not sure exactly about the 2c-x family or mescaline??). The same goes for MDMA, the experience just is not the same, at least IMO, if one tries to roll on the same amount a night after rolling.
Of course, this tolerance (at least for the psychedelics) is rather short-lived. With LSD it lasts about 3-4 days and I think the same for mushrooms. Although I am sure with many drugs acting on serotonin, even if this immediate tolerance is short-term, a longer term tolerance can build for those constantly using/abusing a given drug even if they wait the necessary 3 days for most tolerance to diminish... "losing the magic" so to speak, although this is chiefly a problem with MDMA-- not sure exactly the cumulative effect with constant LSD/psych use.
My question is that, aside from the fact that one can trip/roll on the same substance two days in a row if they simply double (even triple) their dose, if someone is at a particular psychedelic-encouraging atmosphere like a music festival, can they effectively use serotogenic drugs every day of the event (up to 5 days or so) without experiencing any significant tolerance by simply mixing up the drugs they take??
Basically I am referring to loophole of sorts that would allow someone either trip or roll every day, for a much longer period than would normally be possible using the same drug every day, by 'mixing-up' the drug they are using to access psychedelia... perhaps using the same drug twice ONLY after the necessary resting period (during which of course they are not actually 'resting' from psychs altogether) in between doses of that same drug has been taken...
For instance, would any notable dosage increase from the dose I would normally take for each given drug be necessary if one were to follow a type of dosing schedule like this (note that this is an example and the order of each respective drug could be mixed up as one wishes):
Day/Night
1. LSD*
2. 2c-e
3. MDMA
4. Mushrooms
5. 2c-b
6. LSD*
*Assuming that the drug you wanted to take twice, LSD in this case, should be taken on the first night and (at least close to-) the last night to maximize the space or "resting" period in between doses.
Now I am not so hopeful in a plan like this, whether carried out for/at a festival or just used to make a week's vacation from work while staying at home more interesting, that I would expect to use the LSD in the above schedule at the same dose the second time around... after using serotogenic drugs each of the 4 days in between. I am sure that regardless of a normally-sufficient 4 day break from using that particular drug, a somewhat higher dose would still be necessary simply because all of the partying in between. But my main point here is whether the latter trip could be equally as good as the very first one with a dose increase as small as 50%, perhaps more realistically twice the original dose (not bad considering everything consumed between times) and trip *just* as hard as the first??
My primary goal that I am trying to clarify is that perhaps by switching things up so much, the tolerance effect for all the drugs involved is as minimal as humanly (or cosmically!) possible when considering the overall degree of indulgence. Any opinions or experiences with this 'loophole' issue??
Thanks in advance to anyone who can provide some kind of feedback. I know this may be a bit confusing and long, but I tried to make this as clear as I could because tolerance and adaptation to drug-effects with all recreational substances is a menace
.
Most people are aware of a notable tolerance formed to most serotogenic drugs with consecutive days' usage. It is well documented that with nearly all psychedelics that this tolerance prevents the user from experiencing the same level of effects from identical doses used the previous night... whether it be LSD, psylocybin, etc. most of them do (not sure exactly about the 2c-x family or mescaline??). The same goes for MDMA, the experience just is not the same, at least IMO, if one tries to roll on the same amount a night after rolling.
Of course, this tolerance (at least for the psychedelics) is rather short-lived. With LSD it lasts about 3-4 days and I think the same for mushrooms. Although I am sure with many drugs acting on serotonin, even if this immediate tolerance is short-term, a longer term tolerance can build for those constantly using/abusing a given drug even if they wait the necessary 3 days for most tolerance to diminish... "losing the magic" so to speak, although this is chiefly a problem with MDMA-- not sure exactly the cumulative effect with constant LSD/psych use.
My question is that, aside from the fact that one can trip/roll on the same substance two days in a row if they simply double (even triple) their dose, if someone is at a particular psychedelic-encouraging atmosphere like a music festival, can they effectively use serotogenic drugs every day of the event (up to 5 days or so) without experiencing any significant tolerance by simply mixing up the drugs they take??
Basically I am referring to loophole of sorts that would allow someone either trip or roll every day, for a much longer period than would normally be possible using the same drug every day, by 'mixing-up' the drug they are using to access psychedelia... perhaps using the same drug twice ONLY after the necessary resting period (during which of course they are not actually 'resting' from psychs altogether) in between doses of that same drug has been taken...
For instance, would any notable dosage increase from the dose I would normally take for each given drug be necessary if one were to follow a type of dosing schedule like this (note that this is an example and the order of each respective drug could be mixed up as one wishes):
Day/Night
1. LSD*
2. 2c-e
3. MDMA
4. Mushrooms
5. 2c-b
6. LSD*
*Assuming that the drug you wanted to take twice, LSD in this case, should be taken on the first night and (at least close to-) the last night to maximize the space or "resting" period in between doses.
Now I am not so hopeful in a plan like this, whether carried out for/at a festival or just used to make a week's vacation from work while staying at home more interesting, that I would expect to use the LSD in the above schedule at the same dose the second time around... after using serotogenic drugs each of the 4 days in between. I am sure that regardless of a normally-sufficient 4 day break from using that particular drug, a somewhat higher dose would still be necessary simply because all of the partying in between. But my main point here is whether the latter trip could be equally as good as the very first one with a dose increase as small as 50%, perhaps more realistically twice the original dose (not bad considering everything consumed between times) and trip *just* as hard as the first??
My primary goal that I am trying to clarify is that perhaps by switching things up so much, the tolerance effect for all the drugs involved is as minimal as humanly (or cosmically!) possible when considering the overall degree of indulgence. Any opinions or experiences with this 'loophole' issue??
Thanks in advance to anyone who can provide some kind of feedback. I know this may be a bit confusing and long, but I tried to make this as clear as I could because tolerance and adaptation to drug-effects with all recreational substances is a menace

Last edited: