I recently acquired 80mg of alprazolam powder from a fairly reliable source. I am currently going through methadone withdrawal, and I know I shouldn't be switching one addiction for another, but I'm not going to be taking it all the time or anything. I just need something for the nights that I lay awake in bed all night.
Now, I'm only going to be taking it orally. The thing with this powder is to measure out a dose (1-2mg) is next to impossible. I have a milligram scale, but ironically it has an error margin of 1-2mg. I did weigh the powder on the scale to ensure it was 80mg. My first thought was to make a liquid solution, something I had easily done many times before. However, I soon discovered that alprazolam isn't water soluble. My only options were this PG stuff that I couldn't find, 99% ISOP which I don't have nor am I comfortable consuming, or as a last resort 40% alcohol.
So I got a jar an poured in my 80mg of powder. I found on the internet that alpraz is soluble at 2mg/mL with 99/100% alcohol. Since my alcohol is 40% I multiply 0.4 by 2 and end up with 0.8mg/mL. 80/0.8=100mL. I have, however, on various webpages seen the solubility range from 1-3mg/mL and sometimes even higher. To be safe, I add 120mL of 40% (80 proof) vodka to the jar.
I have also read that when using "weak" 40% alcohol that heat should be added to aid in the absorption. I warm up some water on the stove (not until boiling point) and add 80mL to the jar. I give the jar a light shake every once in a while. The jar now contains 180mL of liquid. I also leave the jar in the hot water pot for 5-10 minutes to add even more heat.
I, like everyone, absolutely hate the taste of alprazolam powder. I also hate the taste of hard liquor. I use an eye dropper to drop a couple drops in my mouth and the stuff is absolutely horrid, almost making me sick. I decide to dilute it with some fruit juice. I meant only to pour in a few splashes but my hands slipped and I almost doubled the contents of the jar. The total liquid in the jar was now up to 350mL.
Now I have my solution made. My only question is, when I calculate dosage, do I only include the amount of alcohol in the jar? Or do I include the entire liquid contents of the jar?
If I take into account only the alcohol that I added, first I must remember that I added 120mL of alcohol instead of 100mL. 100/120=0.833 0.833x0.8=0.666mg/mL
So in this case it would be 1mg/1.5mL
OR
Does the alcohol/alpraz dilute with the water/fruit juice? In this case the math would be 100/350=0.285 0.285x0.8=0.228/mL
In this case it would be 1mg/4.4mL
This is a pretty drastic difference and I want to stay safe. Any help is much appreciated!
Now, I'm only going to be taking it orally. The thing with this powder is to measure out a dose (1-2mg) is next to impossible. I have a milligram scale, but ironically it has an error margin of 1-2mg. I did weigh the powder on the scale to ensure it was 80mg. My first thought was to make a liquid solution, something I had easily done many times before. However, I soon discovered that alprazolam isn't water soluble. My only options were this PG stuff that I couldn't find, 99% ISOP which I don't have nor am I comfortable consuming, or as a last resort 40% alcohol.
So I got a jar an poured in my 80mg of powder. I found on the internet that alpraz is soluble at 2mg/mL with 99/100% alcohol. Since my alcohol is 40% I multiply 0.4 by 2 and end up with 0.8mg/mL. 80/0.8=100mL. I have, however, on various webpages seen the solubility range from 1-3mg/mL and sometimes even higher. To be safe, I add 120mL of 40% (80 proof) vodka to the jar.
I have also read that when using "weak" 40% alcohol that heat should be added to aid in the absorption. I warm up some water on the stove (not until boiling point) and add 80mL to the jar. I give the jar a light shake every once in a while. The jar now contains 180mL of liquid. I also leave the jar in the hot water pot for 5-10 minutes to add even more heat.
I, like everyone, absolutely hate the taste of alprazolam powder. I also hate the taste of hard liquor. I use an eye dropper to drop a couple drops in my mouth and the stuff is absolutely horrid, almost making me sick. I decide to dilute it with some fruit juice. I meant only to pour in a few splashes but my hands slipped and I almost doubled the contents of the jar. The total liquid in the jar was now up to 350mL.
Now I have my solution made. My only question is, when I calculate dosage, do I only include the amount of alcohol in the jar? Or do I include the entire liquid contents of the jar?
If I take into account only the alcohol that I added, first I must remember that I added 120mL of alcohol instead of 100mL. 100/120=0.833 0.833x0.8=0.666mg/mL
So in this case it would be 1mg/1.5mL
OR
Does the alcohol/alpraz dilute with the water/fruit juice? In this case the math would be 100/350=0.285 0.285x0.8=0.228/mL
In this case it would be 1mg/4.4mL
This is a pretty drastic difference and I want to stay safe. Any help is much appreciated!