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Opioids Codeine Sickness

K-Dazed

Bluelighter
Joined
Jan 18, 2010
Messages
629
Location
Canada
Hey, I've been feeling very ill the past couple of weeks, and yesterday I bought some AC&C (Aspirin, Caffeine, Codeine), and took roughly 160mgs of Codeine after I CWE it. Everything was fine, it decreased the pain, until around 6 hours after ingestion. I started to feel very gaseous and nauseous, so I went to bed. The next morning I had the worst abdominal pains of my life, nausea, vomiting and extreme blurred vision. After puking my guts out I feel a bit better now (exactly 24 hours after ingestion), but I still feel weak.

Now, I know no one here is my doctor, but I do have some questions:

1) Has anyone experienced this from Codeine? Before this, even at higher doses, I've had nothing but neutral or somewhat pleasant experiences, but I'm never taking Codeine again after this incident.
2) Do you think there's some way I screwed up the CWE (I filtered it twice...) and ingested a bunch of ASA? I'm not a dumbass and I know how to do a CWE, but while I felt like I was dying this passed through my mind. At max I only ingested 7 grams ASA, which isn't deathly, but I think I'm just over-thinking things after taking too high of a Codeine dose and feeling the effects of it (no tolerance, as I said I've been previously ill the past weeks). I understand ASA isnot soluble in water, but is there a chance some of it could dissolve? Because I feel much better now, and did the CWE properly, I don't think it is this, but everything I've been reading on Codeine says most people get sick immediately, while in liver failure cases symptoms show 10h+ after.
3) Does anyone know of anything I can take to help relieve the nausea and constipation from Codeine? I really want to shit, as I believe it'll help this gaseous sensation I have, however all of the meds I have read, "Do not take if experiencing Abdominal Pains, Blurred Vision, Vomiting and Fever" which is all symptoms I have..

Thanks. Just thought I'd ask these questions because this has never happened to me with Codeine. If I've ever felt bad after it, it was an hour or two after ingestion, not the morning after.
 
Aspirin overdose is the first thing that comes to my mind.

Symptoms may range from mild nausea and vomiting, abdominal pain, lethargy, tinnitus, and dizziness to severe such as seizure or cerebral edema depending on the dose consumed.

Because of what you said, and my own experiences with codeine, this is really not normal, especially 6 hours after ingestion.
The only thing that may cause abdominal pain is the constipation that comes with any opiates. But I don't think that's your problem.

Can you detail your CWE? What kind of filters did you use, did you use cold/hot water? Did you let it sit in the fridge so a sludge layer forms at the bottom? Or did you do a hasty CWE? If you do know how to do a proper CWE, then I can't give you any advice other than to actually do it.

It really is very very very stupid to do a hasty CWE. Fuck these pharma motherfuckers thinking they can make codeine un-abusable by mixing it with aspirin/apap/ibuprofen/caffeine. Fuck them by doing a proper CWE. It's really annoying to OD on aspirin and shit like that.

Take some laxatives for your other problem.
 
is this your first time using codeine or any opiates in general?

If it is, the nausea makes sense, and so does the lethargy and fatigue, even 24 hours later. I've done opiates before, but the first time i experienced bad lethargy was after i used poppy seed tea for the first time, the whole next day I was super fatigued and lethargic, i actually had sore quads so i thought I was some how experiencing withdrawals lol. And I'd done many a cwe codeine ranging from 100-350mg before this, so it was weird.

Then I didn't experience this again until I used oxy for my second time ever yesterday, 15mg had me sleep for 11 hours straight cause I was to weak to really stay awake (not slow breathing or heartrate, just feeling like i'd ran a marathon, this was hours after ingesting). Even now 28 hours later I'm still feeling slightly nauseos and still fatigued and a bit lethargic. I never puked though cause I was popping 25mg of benadryl every 4 hours to counter the nausea, this could also be causing or a contributing factor to the fatigue though so idunnolol.

Anyways, just to be on the safe side I'd go to the ER, ESPECIALLY if your symtoms get worse. Because say you used a fail filter that wasn't tight enough or you just f*Cked up some how, you coulda possibly ingested 6g of apap at once. This is a very very dangerous dose, especially at once, anything over 3-4g of apap a day can cause serious liver problems.

Anyways, stay safe.

EDIT: mis-read aspirin for tylenol but aspirin is just as dangerous. Can cause serious blood thinning and stomache ulcers and internal bleeding and all sorts of other fun stuff, my advice still stands go to the ER to be safe, but definetly go if you get any worse feeling.
 
is this your first time using codeine or any opiates in general?
nope

1) Has anyone experienced this from Codeine? Before this, even at higher doses, I've had nothing but neutral or somewhat pleasant experiences, but I'm never taking Codeine again after this incident.
 
sorry, I skim, I don't read. Bad habit lol, has caused me many-a-problemos.

EDIT: To OP, have you done anything that mighta strained your abs this week? crunches, maybe some sort of lifting that would have worked your core.

After not doing crunches for over a year, I did some one day and 4 days later my abs / lower abs / upper pubis area was in absolutely extruciating pain. I could barely move. I thought for sure I was dieing, unrelated to the crunches I'd done cause I'd never felt such soreness before.

By the 6th day I was basically fine again though, I'd went to the doctor just to be sure but he quickly dismissed me after I told him I'd taken a shit that morning (regular bowel movement), and that the pain was caused specifically by trying to move/moving. I'm a hypochondriac though lols.
 
It's unusual that you got the nausea 6 hours later. If it was opioid-related I would have thought it would come on earlier, and especially as you have taken higher doses with no ill effects in the past.

Difficult to say whether you messed up the CWE - sounds unlikely, could you talk us through what you did?

Aspirin is not freely soluble in water. According to this excellent CWE megathread, 1g can dissolve per 100mgs of cold water. How much water did you use, and

The most likely culprit in my mind is the caffeine. I have a friend who was hospitalised with vomiting after eating a load of caffeine tablets. It irritated his stomach, causing a mild internal bleed. I would suggest getting yourself checked over by a doctor, even though you are recovering, to make sure everything is okay and maybe check your bloods.. caffeine is water soluble, so will not have been removed by the CWE.

It might be unrelated as well, and just a coincidence with the timing - without being examined by a medical professional it is very hard for us to say, especially over the internet..

As for nausea, I find 1st generation antihistamines (eg promethazine, diphenhydramine, hydroxyzine) to be pretty effective. Ginger is good too. Here in the UK you can also get prochlorperazine OTC, which is an antiemetic. Constipation - keep well hydrated, eat lots of fibre and some fat/oil, keep active, and if you want to try medication then your best bet is a prokinetic/stimulant laxative such as senna or bisacodyl along with a softener such as PEG or docusate. Bulking agents like Fybogel/isphagula hulk can work, but they can also just cause obstruction in the inactive gut caused by opioids..
 
Are you sure you're not just getting more sick?

I throw up a lot on opiates and I used to have a nasty habit with them. I would throw up majority of the times I took them which is ridiculous because I've abused them for almost 2 years
 
If you took too much apap it could be some sort of renal (liver) problem which will kill you if you dont go to the ER. However I know that for me personally codeine is the only opiate I cannot take. It gives me pulminary edema, which is when your lungs fill with fluid. Thats ironic because when I found this out I was prescribed it for pneumonia. Anyway if this continues and your eyes and or skin begin to turn yellow, go see a doctor immediately.

Edit.

APAP causes more deaths than any other medicine on the market due to renal failure. FYI
 
^ Indeed, except the OP didn't ingest any APAP :)

APAP overdose is indeed a medical emergency, however. I am sorry to hear about the pulmonary oedema, it's pretty rare orally but not unheard of, due to the huge histamine release you can get with codeine..
 
Yeah, I'm not turning yellow or anything, and feeling better, so I don't think it's the ASA, just a bad reaction to the codeine.

I've been sick the past two week, which possibly could have played a roll, but I've felt fine since tuesday (though I was vomitting monday). The reason I took the codeine was partially because I've been sick.

For the CWE, I got warm (not hot) water, put the pills in, played it in a container full of ice for around 25 min. Placed my finger in it, it was cold. Got coffee filter, poured it into the cup. I let it drip for a while (15 min), but then when I went to go get the excess sludge, I added to much water, and when I poured it into the filter and left, I came back and the water was up to the filter. So I got a new cup, filtered my cup a last time (there was no sludge in the final product I drank, slightly white tinge but not milky) then drank it.

I started feeling gaseous around 2 hours in, but not sick until 6 hours after ingestion.

I feel better now, ~26 hours after. Would I be dead or severely sick by now I my liver was failing? I assume so. ATM because I was sick (for like the past 2 months..) I quit all drugs, and have don't opiates since October, so I think I could just feel "hungover" after a small OD? I haven't vomited in 6 hours and I've been able to eat a bit (when before I'd vomit it up). I also never take caffeine.

I smoked a bit of weed recently and felt better. Told my self after I was puking (6 hours ago) I would go to the ER if I felt worse, but I've been feeling better. I'd sure be feeling worse now 26 hours after ingestion if my liver was failing?
 
Don't worry about your liver, you didn't consume APAP so that's fine.

You could have ended up with some aspirin in your filtrate, I find if I have to mess about with it all (refiltering etc) it tends not to work as well - but it sounds like overall it was okay. Ideally you want clear liquid, but some preparations don't allow this, so it is good to become familiar with what your filtrate usually looks like when it is done properly.. you can calculate the amount of aspirin in your water by looking at the total volume and the solubility (1g/100ml). As long as you use a good filter and don't squeeze it etc you should get most/all of the solids out.

My money is still on the caffeine, as this can definitely cause nausea and irritate the stomach. Aspirin can too, and both can cause internal gastro-intestinal bleeding - if you notice any blood in your stools, or dark/black/tarry stools, or if you vomit any blood then it is important to get yourself checked out ASAP.

I'm really glad you're feeling better :) for safety's sake I would still get checked out, but it sounds like you are over the worst.
 
Yeah, the more I've been researching, the more I don't think it's the Aspirin, but the Codeine. All my other Codeine experiences I took more Codeine (200mg+), but I guess because I've been feeling ill and had no tolerance I had a minor overdose. I feel much better now, still getting a little bit of stomach pain and nausea, with a bit of blurred vision but I don't feel like I'm going to die anymore, I can eat, and I can drink. I have a doctor's appt for tomorrow anyways, so I'll be sure to bring this up. Every other time I've taken Codeine I've had severe itching, but this time it wasn't a problem (I normally combine it with dramamine, but didn't this time).

Also, there's no way I drank more than 500ml of liquid (I think 400ml is still pushing it, probably drank around ~350ml). If only 1g of Aspirin dissolves in 100ml, I should be fine? The first time I filtered it, I didn't rush whatsoever, but the second time I rushed it and squeezed it a little - it (the filter) didn't break however.

It seems other people get Codeine hangovers, and it could have possibly been the Caffeine as well. Even though I have a doc appt tomorrow I'll probably never know the cause, as caffine codeine and ASA overdoses all have the same vague symptoms (headaches, nausea, vomiting, blurred vision etc) that I was/am experiencing.
 
Hey, I've been feeling very ill the past couple of weeks, and yesterday I bought some AC&C (Aspirin, Caffeine, Codeine), and took roughly 160mgs of Codeine after I CWE it. Everything was fine, it decreased the pain, until around 6 hours after ingestion.

Could it be that you were feeling ill for a few weeks and the codeine dose actually made you feel better, but once the codeine started to wear off your "sick/ill" feeling became more noticable again.
Maybe you have/had a stomach flu or bug and the codeine worked on the symptoms until it wore off.
Maybe try and get to a doctor for a diagnosis on why you are not feeling well - IMO it was an underlying bug/flu.

Just my 2 cents.
Hope you feel better soon.
 
Yeah, got my blood taken and no ASA was there, as I thought (I've done a CWE hundreds of times, wouldn't believe I fucked it up). Only reason I thought it could've been ASA is because I was getting sick much later, not immediately after. They said it was probably due to the fact that I've been sick the past while, wasn't eating, and that the codeine & caffeine agitated my stomach. Feel much better today. Thanks everyone though.
 
codeine is also known to be one of the most heavily "side effects filled" opiates, often causing severe itching and nausea, even though you don't get very much of an opiate high.

Always take an anti-histamine before codeine doses imo.
 
1st generation antihistamines are excellent for itching, nausea and added sedation. The only issue with codeine is they can inhibit the enzymes needed to convert it to it's active metabolites. 2nd generation antihistamines aren't as good for nausea and aren't sedating, but don't generally affect liver enzymes as much.

I still think the caffeine played a role. Pills with caffeine in aren't suitable for CWEing as the caffeine is water soluble and is not removed, so you will end up with too high a dose. It definitely can cause both nausea and gastric irritation.
 
Yeah, I think it was the caffeine too. Like I've said, I've taken Codeine before, and I normally take it with an anti-histamine (normally benadryl or dramamine) and normally I itch like crazy. This time I didn't itch, got a little high, then felt sick 6 hours after ingestion with gas and nausea. Woke up with blurred vision, and had severe abdominal pain and itches after I had woken up. I was feeling restless, irritable and very, very sick (and I've been puking the past weeks and it wasn't that type of minor pain, it was searing pain in my abs). I'm sure it didn't help that I wasn't eating. I was looking up symptoms for codeine overdose and caffeine overdose, and I'd say caffeine fits the bill more than most. Didn't think 300mg of Caffeine was that much, considering I was looking online and some people were saying that's how much is in a cup of coffee (?). Again, I don't drink pop or coffee, so I have no tolerance to caffeine (or codeine for that matter, most likely).

Anyways, thanks again. Mods can feel free to close this, or keep it open in case other people suffer the same symptoms. Nonetheless thanks.
 
Glad you checked it out.
The docs cant get you in trouble for it and its always better to be safe than sorry.
 
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