Opioids Codeine + DHC [Overcoming Theoretical Max Dosage]

[saadman]

My tolerance has long since exceeded the codeine threshold but my understanding is that DHC is active without needing to be metabolised.

So my current method is to take a mixture of both, around 600mg codeine and about 600mg DHC.

I take them together at the same time but I was thinking… my understanding is that DHC also metabolises via the same mechanism as codeine, therefore it might be stealing the enzymes needed to make the codeine active.

Would I be better to take the codeine first and then after a time take the DHC?

If so, how long should I wait before dosing the DHC.

By the way both are dissolved in water solution and taken orally, so no time is needed to be considered for the breakdown and absorption of pills.

 

[Gridlink]

If your concern is that DHC and codeine are competing for the same liver enzyme, and your tolerance has surpassed the ceiling dose of codeine (which is ~400 mg I thought), well, given that DHC is stronger than codeine and has no ceiling dose, why wouldn't you just take more DHC and shun the codeine altogether? Is there some reason you really have to take both instead of just taking, say, 900 mg DHC?

 

[saadman]

If your concern is that DHC and codeine are competing for the same liver enzyme, and your tolerance has surpassed the ceiling dose of codeine (which is ~400 mg I thought), well, given that DHC is stronger than codeine and has no ceiling dose, why wouldn't you just take more DHC and shun the codeine altogether? Is there some reason you really have to take both instead of just taking, say, 900 mg DHC?

Because codeine is lovely
You’re question could be rephrased as why not just leave your wife and go full time with your side piece

But yea, you understand my reasoning perfectly. I just want advice on whether to take them together not to leave 5, 10 or x mine between dosages.