I’m an endurance athlet trying to understand doping tests better – hope for your inputs and assistance in clarifying detection times.
The traditional method of detecting abuse of testosterone looks for an imbalance in the ratio of testosterone and epitestosterone. It is referred to as the T/E ratio test. A normal ratio for most humans is near 1:1. The World Anti-Doping Agency (WADA) considers a ratio over 4:1 to be a positive test. But testosterone/epitestosterone ratios return to normal quickly, even overnight if taken in the right doses, why one can use small amounts of testosterone for doping, i.e. improved performance and recovery.
But there is a test that can detect even though that bespoke T/E ratio has returned to normal and that is the Carbon Isotope Ratio (CIR). Labs determine the quantities of carbon-12 and carbon-13, two isotopes, or types, of carbon, within an individual’s testosterone molecules. Synthetic testosterone has less carbon-13 than naturally occurring testosterone. Synthetic testosterone has less carbon-13 than naturally occurring testosterone.
Until very recently, the procedure from WADA has been to 1) test for the T/E ration and if, and only if, above 4:1, then 2) use the Carbon Isotope Ratio. This leaves a window of opportunity for using testosterone up to the level of, let’s say, 3,999:1. And that is indeed performance enhancing for an endurance athlet.
The cyclist Tom Danielson was busted by CIR (Carbon Isotope Ratio), but appently the CIR test was used as a step 1, i.e. without Tom Danielson being the above the 4:1 ratio. USADA determined that the ratio between carbon-12 and carbon-13 isotopes in Danielson’s testosterone molecules did not match the ratio that occurred naturally in the rest of his body. A synthetic form of the hormone had to be present. How it got there will be the crux of Danielson’s defense, but its presence is undisputed thanks to CIR.
Please look into the article here: http://velonews.competitor.com/2015/08/news/the-test-that-caught-tom-danielson_381086
My question to all you wise people: for how long time can the Carbon Isotope Ratio test detect endogenous testosterone, let’s say a product like Andriol testo-caps?
The traditional method of detecting abuse of testosterone looks for an imbalance in the ratio of testosterone and epitestosterone. It is referred to as the T/E ratio test. A normal ratio for most humans is near 1:1. The World Anti-Doping Agency (WADA) considers a ratio over 4:1 to be a positive test. But testosterone/epitestosterone ratios return to normal quickly, even overnight if taken in the right doses, why one can use small amounts of testosterone for doping, i.e. improved performance and recovery.
But there is a test that can detect even though that bespoke T/E ratio has returned to normal and that is the Carbon Isotope Ratio (CIR). Labs determine the quantities of carbon-12 and carbon-13, two isotopes, or types, of carbon, within an individual’s testosterone molecules. Synthetic testosterone has less carbon-13 than naturally occurring testosterone. Synthetic testosterone has less carbon-13 than naturally occurring testosterone.
Until very recently, the procedure from WADA has been to 1) test for the T/E ration and if, and only if, above 4:1, then 2) use the Carbon Isotope Ratio. This leaves a window of opportunity for using testosterone up to the level of, let’s say, 3,999:1. And that is indeed performance enhancing for an endurance athlet.
The cyclist Tom Danielson was busted by CIR (Carbon Isotope Ratio), but appently the CIR test was used as a step 1, i.e. without Tom Danielson being the above the 4:1 ratio. USADA determined that the ratio between carbon-12 and carbon-13 isotopes in Danielson’s testosterone molecules did not match the ratio that occurred naturally in the rest of his body. A synthetic form of the hormone had to be present. How it got there will be the crux of Danielson’s defense, but its presence is undisputed thanks to CIR.
Please look into the article here: http://velonews.competitor.com/2015/08/news/the-test-that-caught-tom-danielson_381086
My question to all you wise people: for how long time can the Carbon Isotope Ratio test detect endogenous testosterone, let’s say a product like Andriol testo-caps?
