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  • BDD Moderators: Keif’ Richards | negrogesic

Opioids Can you smoke morphine pills?

Id suggest not smoking any kind of pill honestly, they have all sorts of other shit in them like binders and fillers. Who knows what the hell that can do to your lungs, when you goto vape that pill all thats vapor/smoke coming off the foil is not just the morphine you know. If you wanna get more bang for your buck i would plug them.
 
You could theoretically crush/mix the pills with water and run them through a wheel filter. Then take the filtrate and slow-evaporate off the water, and smoke whatever solid is left. You might still end up smoking pill additives though. And I don't think this would work with extended release morphine at all.

The other issue is that the active ingredient in the pills may be destroyed with heat. It is not in resin form like some other opiate compounds, so it has no protection from heat degradation.

You should just plug it.
 
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It is smokable but obviously there is waste, the formulation makes a big difference. I have somebody in the past, I’m clean now and don’t recommend smoking morphine ginger high but i think the “cleanest” way to do what you’re asking with time release pills would be to crush and mix with weed/tobacco/smoking blend and smoke in a bong.
 
Smoking Morphine is a waste of time. You would have to turn it into a base first and then let it dry out. I would just stick to snorting them or just popping them.
 
To freebase Morphine tablets. Dissolve in a small amount of water. Add Cacium Carbonate untill a pH of 9.1 is reached. Which leaves you with Cacium Morphinate, the base. The base is kept and the liquid is thrown away. The base is left out to dry. Once it's dried out you have smokable Morphine base. Don't expect it to be processed and smokable in minutes. It takes a wile.
 
Oh, and... If you don't have Cacium Carbonate you can substitute it with Sodium Bicarbonate.
 
I was once given about 50x 10mg morphine capsules. Just small capsule containing little white spheres. It was tricky to separate them and crush them up but 1 cap snorted equalled about 5 caps swallowed (morphine only has about 20% bioavailability).

To smoke morphine you must freebase it or it's an utter waste.

Never tried plugging them BUT the bioavailability is almost certainly a lot higher than oral route.

Of course in some nations people buy up morphine tablets to make H. But I note only in nations where H costs a LOT (Australia and New Zealand).
 
MedicinalUser247 said:
To freebase Morphine tablets. Dissolve in a small amount of water. Add Cacium Carbonate untill a pH of 9.1 is reached. Which leaves you with Cacium Morphinate, the base. The base is kept and the liquid is thrown away. The base is left out to dry. Once it's dried out you have smokable Morphine base. Don't expect it to be processed and smokable in minutes. It takes a wile.
Click to expand...

Would that really work?

Is calcium morphinate actually a freebase?

AlsoTapered said:
I was once given about 50x 10mg morphine capsules. Just small capsule containing little white spheres. It was tricky to separate them and crush them up but 1 cap snorted equalled about 5 caps swallowed (morphine only has about 20% bioavailability).

To smoke morphine you must freebase it or it's an utter waste.

Never tried plugging them BUT the bioavailability is almost certainly a lot higher than oral route.

Of course in some nations people buy up morphine tablets to make H. But I note only in nations where H costs a LOT (Australia and New Zealand).
Click to expand...

Were those slow-release morphine capsules the brand name ZoMorph?

Morphine has an average oral bioavailability of 33%.

A few people have said that the morphine should be snorted, morphine only has a bioavailability next of 5% to 10%, it’s a real waste snorting morphine.

Could people do something similar to what Aussies and New Zealanders do where they make H from morphine tablets but also do it like the Mexican cartels do, where they use acetic acid instead of acetic anhydride, so you only acetylate the 6 position, making 6-monoacetyl-morphine (6-MAM)?
 
Gaz_hmmmm said:
Would that really work?

Is calcium morphinate actually a freebase?



Were those slow-release morphine capsules the brand name ZoMorph?

Morphine has an average oral bioavailability of 33%.

A few people have said that the morphine should be snorted, morphine only has a bioavailability next of 5% to 10%, it’s a real waste snorting morphine.

Could people do something similar to what Aussies and New Zealanders do where they make H from morphine tablets but also do it like the Mexican cartels do, where they use acetic acid instead of acetic anhydride, so you only acetylate the 6 position, making 6-monoacetyl-morphine (6-MAM)?
Click to expand...


Here is how Afghan's convert opium to H. Page 13 goes through each step with a paragraph on each. Be it extracting morphine from opium or morphine from pills, the same chemical processes are used.


It's derived from the above patent. Calcium is preferred because calcium morphinate is fairly soluble in hot water, almost insoluble in cold water so it's more convenient.
 
AlsoTapered said:

Here is how Afghan's convert opium to H. Page 13 goes through each step with a paragraph on each. Be it extracting morphine from opium or morphine from pills, the same chemical processes are used.


It's derived from the above patent. Calcium is preferred because calcium morphinate is fairly soluble in hot water, almost insoluble in cold water so it's more convenient.
Click to expand...

So would turning it back in to a salt i.e. cooking it up, remove the calcium?

Another thing, would using acetic acid (Say 80%?) on the calcium morphinate, kinda like how the Mexicans use it to make black tar heroin, acetylate the 6 position, thus making 6-monoacetyl-morphine (or morphinate in this scenario?).?

I have seen a lot of info and step by step guides on how Heroin is made and how the Afghan’s do it and those in South East Asia but I’ve never seen a step by step guide on how the Mexicans do it.
All I know is that they take raw opium and just acetylate it with acetic acid, making what is called ‘black tar heroin’ but really acetylated opium with acetylcholine and 6-monoacetyl-morphine within it along with other opiates found in opium like thebaine, oripavine, papaverine and noscapine etc.
 
Reading through a 1963 UNODC paper on the synthesis of 'heroin' notes the common methodology employed in Mexico.

Taken from:

Title: XLIX.—On the action of organic acids and their anhydrides on the natural alkaloïds. Part I
Series: Journal of the Chemical Society (Resumed) vol. 27 iss. 0
Author(s): Wright, C. R. A.
Publisher:
Year: 1874

Action of Acetic Acid on Morphine.

When morphine is boiled for several hours with twice its weight of glacial acetic acid, an inverted condenser being attached, a large amount is converted into a substance related to morphine in the same manner beta diacetyl-codeine is to codeine (NOTE - 6 ACETYLATION).

By dissolving the product in water, adding ammonia, and shaking up with ether, an ethereal solution is obtained which yields a copious crystalline hydrochloride on shaking with hydrochloric acid ; this hydrochloride is but sparingly soluble in cold water, but can be recrystallised from that menstruum when hot (NOTE Isolation of 6-MAM as hydrochloride salt).

A warm aqueous solution of the salt yields with ammonia a flocculent non-crystalline precipitate, readily soluble in ammonia, sodium carbonate, caustic potash, ether, alcohol, and benzene; from the latter three solutions it separates on spontaneous evaporation as a gummy film, wholly destitute of crystalline characters (NOTE - FREEBASE 6-MAM).


Note that no yield is given. I have read variations on the above in which small amounts of sulfuric acid are added to the glacial acetic acid to increase yield. This makes sense as it is known that sulfuric acid + morphine yields the somewhat unstable morphine-6-sulphate.

But neither GAA nor sulfuric acid are difficult to acquire but if memory serves, Wright only achieved a 100% M-->6-MAM conversion by placing the morphine and glacial acetic acid into a sealed tube and heating it to 160C. The use of a sulphuric acid catalyst may well overcome this issue.

It's clear that each region of 'heroin' production relies on 'cooks' teaching 'cooks' with no reference to advances in scientific research. At the other end of the spectrum, in SE Asia a 'cold' method of heroin production had been introduced in which trifluoroacetic acid is added to the acetic anhydride/morphine solution which likewise acts as a catalyst.

All of the UNODC data is based on the forensic examination of samples. I PRESUME that SE Asian heroin contains traces of the trifluoroacetic esters, Afghan and Mexican heroin contains traces of 6-monoacetyl codeine and Mexican heroin still contains some unreacted morphine freebase.
 
ChemicallyEnhanced said:
Problem with that is that snorting them has an even lower bioavailability than oral. Is there a rush that's worth that?
Click to expand...

jpet.aspetjournals.org

Intranasal Delivery of Morphine

Morphine administered nasally to humans as a simple solution is only absorbed to a limited degree, with a bioavailability of the order of 10% compared with intravenous administration. This article describes the development of novel nasal morphine formulations based on chitosan, which, in the...
jpet.aspetjournals.org jpet.aspetjournals.org

No, morphine has a MUCH higher bioavailability when snorted as compared to swallowed. If you mean the pills you are considering make snorting difficult, inefficient and/or plain nasty then fair enough, but ANY route that avoids the stomach avoids first-pass metabolism by the liver which is 80-90%.
 
AlsoTapered said:
jpet.aspetjournals.org

Intranasal Delivery of Morphine

Morphine administered nasally to humans as a simple solution is only absorbed to a limited degree, with a bioavailability of the order of 10% compared with intravenous administration. This article describes the development of novel nasal morphine formulations based on chitosan, which, in the...
jpet.aspetjournals.org jpet.aspetjournals.org

No, morphine has a MUCH higher bioavailability when snorted as compared to swallowed. If you mean the pills you are considering make snorting difficult, inefficient and/or plain nasty then fair enough, but ANY route that avoids the stomach avoids first-pass metabolism by the liver which is 80-90%.
Click to expand...

Morphine has a ~30% bioavailability when taken orally. According the that link it has a 10% bioavailability when snorted. That means taking it orally is three times stronger.
 
This article describes the development of novel nasal morphine formulations based on chitosan, which, in the sheep model, provide a highly increased absorption with a 5- to 6-fold increase in bioavailability over simple morphine solutions.
 
If it were me, I would plug.

Pure morphine zero contaminants or excipients MAY be another matter ofc but it IS a chemical mostly smoked are just wrong, I know Crack and Meth are almost two relative exceptions but plain cocaine or MDMA...Ketamine I kept line drawn.


Heroin ofc yes. Anyhow. I chose myself to insufflate that sporadic situations, for one it staved me off ever even prospecting to begin "using"


Foil toxicity, earlier dementia MUST be an under recognised factor with "brown heads" lol.


But smoking tablets = all ingredients DEFINITELY not fit to burn and inhale.
 
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