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Bromadol / Trans-Bromadol / Bromadol HCL

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H8ff0000

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I'm curious as to what the difference between the three forms is? I don't know much about chemistry.

Potential topics of discussion / comparison between them:
Effect
Potency
etc

Edit: Oh and wow... 1st post! I've been lurking here for so long. Never realized I haven't posted yet :)
 
This compound has been discussed in the past and in one case even responded to by the creator (supposedly). Here's an excerpt;
By "Bromadol", I assume that you refer to the hellishly potent compound 1 in our original 1979 Comminication to the Editor" in J.Med.Chem [...] they walked away from the series when that compound showed some weird tox in chronic tests. No details since I was long gone from Kalamzoo by then.
 
Search engines are your friend and given that there are no verifiable human reports who knows. Animal models suggest the trans isomer is the more potent. Freebase ( bromadol) and salt ( hcl),

Is there some of "rc" spambot that routinely posts the same questions about the same overhyped chems ( 2-meo ketamine, 4-EAR., bromadol, etc) of which there is as of yet no human use, and only scams purporting to have such? WTF?!
 
Bromadol has at least 2 chiral centers (on each side of the cyclohexane ring), so the trans isomer is the most potent @ mu opioid receptor. Cis, meso, etc will be less effective. Compare the substituted fenanyls (a=methyl b-hydroxy fentanyl, ohmefentanyl)

HCl denotes whether it is a salt or not, salts are generally soluble where freebases are not.

Bromadol to the best of my knowledge has not been trialed in humans, the closest analog that sees regular use is fentanyl however. (Not a lot of human studies of super potent opioids due to the risk of death & addiction.)
 
Thanks for the chemical info and chemistry tips.

Here's where I was a bit confused:I read (and I'm sure some of you did as well) a personal report of someone who (supposedly) got a hold of Bromadol in base form. However they claimed to have insufflated it. Wouldn't it need to be the HCl form to be used in this manner properly? I could be wrong, this is far from my area of expertise.

(Also as a side note, I found it very strange that it was supposedly mixed with benadryl. Why use something like that?)

I remember reading about a different compound at some point, and someone saying it wasn't very water soluble, and therefore was more effective if eaten. However I appreciate any corrections. Knowledge is power and such haha :)

About fentanyl, I've personally done a decent amount of testing with it (evenly mixed with glucose). It's interesting how something can effect different people in different ways, and how something that is more potent won't actually give the desired effect. I'll admit, I'm curious what the effects of a properly administered dose of this compound would be in comparison to those of fent / H / hydroco / oxyco / etc...
 
Is there some of "rc" spambot that routinely posts the same questions about the same overhyped chems ( 2-meo ketamine, 4-EAR., bromadol, etc) of which there is as of yet no human use, and only scams purporting to have such? WTF?!

I wonder the same thing. I see that H8 replied, but their initial post is suspicious. Especially the "Edit: Oh and wow... 1st post! I've been lurking here for so long. Never realized I haven't posted yet" part as their post doesn't show a history of being edited
 
Bromadol is essentially not sold (& for good reason), II would be extremely wary of people who claim that they purchased or used it.
 
There's a window of a few minutes in which you can edit a post without it showing up at the bottom of the post. Let's not get too crazy.
 
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