Bath Salts V2.0

[Fertile]

I refer you to -

DE Patent 747866-C
'Process for the preparation of 2-phenyl-3-aminobutane'
Inventor(s): HAFFNER F., SOMMER DR FRITZ
Country: Germany
Dates Grant: 1944/10/18
Priority: 1938/09/10

and

US Patent Application 20060234952A1
'Combination therapy for effecting weight loss and treating obesity'

as well as

ZINC1670065 & ZINC1670064

So all 4 enantiomers can be resolved (or a chiral precursor used). I would be looking at patents behind the people who own ZINC. If I had to guess, I would suggest ZINC1670065 might well be as active as dexamphetamine.

 

[Fertile]

Also

US Patents 9302981B2 'Synthesis, methods of using, and compositions of cycloalkylmethylamines'

and

AKOS014039690
'

 

[fastandbulbous]

Personal experience (when I had delusions of being a competent synthetic orgnic chemist) was that replacing the beta methyl group with a beta methoxy, gives a bloody good stimulant and the configuration about the beta methyl carbon doesn't have that much influence on activity (aka O-methylephedrine. Think of it as halfway between meth and phenmetrazine - it's like a ring opened phenmetrazine).

 

[Fertile]

THANK YOU. Those ARE novel so I could not find them. But you cannot argue with personal experience. So will we see people trying to work out how to selectively O-methylate ephedrine?

Actually, I'm sure we both know EXACTLY how to make the class you describe. Of course, after you with the alkylating agents... I insist ;-)

 

[fastandbulbous]

Er, aren't we prohibited from synthesis details?

 

[Fertile]

Well strangely - if it's a patent then it's in the public domain anyway. Let's face it, how many people would actually pick through a patent? Over the years they keep changing terminology and so it's a very long-winded business. How many people on BL would spend a whole day reading and understanding a patent?

 

[fastandbulbous]

Oh dear, makes me realise what a sad bastard I am!

 

[Rectify]

Beta-Methoxy-MA Got Me Jacked. Had To Drink A Bottle Of Champagne. But Since It Was NYE, That Was Ok. Very Good Stim. I Named It METHUSALEH.

I Couldn't Tell You How They Made It. That's YOUR Job.

 

[tamarinds]

Needs a pyrrolidine group that Nitrogen.

 

[Fertile]

Well strangely - if it's a patent then it's in the public domain anyway. Let's face it, how many people would actually pick through a patent? Over the years they keep changing terminology and so it's a very long-winded business. How many people on BL would spend a whole day reading and understanding a patent?

Not to worry - I'm sure sekio will be back soon. A triumvate, possibly?

Bagsy Crassus.