Misc Anyone take Trazodone before? Feedback?

[ShaunG]

So my doctor prescribed this for me for sleep as I taper from Xanax. He said not to take it unless I really needed it to sleep. The reviews I have read for using this drug to sleep seem to be pretty decent for an anti-depressant. I have tried several SSRIs for anxiety and couldn't stand any of them which is how i landed on low dose daily Xanax which I am proactively attempting to get off. I know this is an SARI and not an SSRI, but just wanted feedback. I also can't believe that I read mCPP is a metabolite of this drug? wtf is that? i dont want pipes lol...this can't be good for your kidneys...


Wikipedia

Pharmacokinetics

Trazodone is well absorbed after oral administration with mean peak blood levels obtained at approximately 1 hour after ingestion. Absorption is somewhat delayed and enhanced by food. The mean blood elimination half-life is biphasic: the first phase's half-life is 3–6 hours, and the following phase's half-life is 5–9 hours. The drug is extensively metabolized with 3 or 4 major metabolites having been identified in the human body, particularly mCPP,[43] which may contribute to the side effect profile of trazodone. mCPP has been shown to activate numerous serotonin receptors, including 5-HT2C. Approximately 70–75% of 14C-labelled trazodone was found to be excreted in the urine within 72 hours.[44] Trazodone is highly protein-bound.

As a consequence of the production of mCPP as a metabolite, patients administered trazodone may test positive on EMIT II urine tests for the presence of MDMA ("ecstasy").[45]

 

[twotoomany]

I've taken it before. Knocked me right the fuck out. My buddy has a script. He calls it trazaBONE because he wakes up with a raging boner every time he takes it.

 

[.:Holy::Toast:.]

I wake up with a raging boner all the time haha can be pretty inconvenient at times
Anyway I've never tried it but I was always interested in it due to my insomnia

 

[velmwend]

Trazodone is grrreat for sleep. Your first couple of doses an hour before bed will have you nearly crawling on your hands and knees to get to bed, lol. You may experience side effects for the first week or two then they disappear.

I had to stop taking trazodone due to cardiovascular side effects. It totally cured my insomnia (apart from the occasional natural restless night, like we all get) but it *totally* killed my sex drive...even more so than your modern anti-depressants.

It *is* a great insomnia cure. Just watch your sex drive and heart.

 

[Marie1010]

I've been prescribed and taken Trazodone for years. It may take time to figure what dosage works for you since when I began, it knocked me out too much but now I'm at a good dose. Yes, prepare for bed before you take it since it can hit suddenly. For me it's been very helpful.

 

[Morphling]

Some people seem to think it's just great; a lot of people, like me, also think it's a horrible drug. Hope it works for you!

 

[Crashing]

I think it's terrible. When i first took it in a rehab, it knocked me out cold. But then i tried using it in opiate withdrawal for some sleep and it just gave me a heavy heartbeat with a boner that would not go away. This was really painful and i spent a few hours putting ice on my dick to try to make it go away. That didn't even work, needless to say i go no sleep. After that i decided not to take it ever again.

 

['medicine cabinet']

Absolute worst drug next to seroquel. Makes you feel like a zombie after you wake up 18hrs later, such a horrible feeling. In rehab it was basically the only thing they would give for sleep and after i took it once i decided never again, id rather not sleep that feel like shit all day. They actually tried to force it down everyones throat, i guess to keep ppl chill and zombified. They were giving big doses tho so maybe a really tiny dose would be ok, kinda doubt it tho. Ymmv.

 

[ShaunG]

Trazodone is grrreat for sleep. Your first couple of doses an hour before bed will have you nearly crawling on your hands and knees to get to bed, lol. You may experience side effects for the first week or two then they disappear.

I had to stop taking trazodone due to cardiovascular side effects. It totally cured my insomnia (apart from the occasional natural restless night, like we all get) but it *totally* killed my sex drive...even more so than your modern anti-depressants.

It *is* a great insomnia cure. Just watch your sex drive and heart.

Thats weird since they say increased libido might be a side effect. I can't afford to lose more libido...just getting off opiates and still on Xanax so its not that great right now. I am waiting for that kickback from stopping opiates to happen but it hasn't yet...been 2 weeks.

Some people seem to think it's just great; a lot of people, like me, also think it's a horrible drug. Hope it works for you!

Care to elaborate on why you think it is a horrible drug? mCPP as a metabolite can't be a good thing for your liver and kidneys. Wikipedia mCPP


I have read it is really dose sensitive. My brother told me to try half or a quarter of 50mg for sleep. I have been using xanax which really has no bad side effects on me. I just worry about memory loss and long term benzo use even though I never have upped my dose for GAD (.5mg), only panic attacks (to 1mg) over 3 years. I am not comfortable switching the two if I need something every night for sleep so this is supposed to be just until I am off the xanax. I did read about the boner thing with Trazodone too. Its like Viagara...boner for more than 4 hours then go to the hospital or take some psuedophedrine and try to wait it out. I guess this is a small percent of people (.5mg), but I have had that happen when I took a random Cialis on blow one night. I would piss, it would go down a little, I would go to sleep, and wake up to a raging boner again and cycle throughout the night every 2 hours until i got up the next day. I hope I don't have this with Trazadone too.