YES! I've had fatigue since the age of 12 (14 years) with no official diagnosis. Been tested for hypothyroidism, anemia, diabetes, food allergies, heavy metal toxicity and others, all of which were negative. I suspect some sort of autoimmune thing like endometriosis or celiac disease, but it could also be something simple like depression. I honestly have no idea.
I was briefly prescribed Provigil in college. It prevented me from sleeping but did nothing for the fatigue itself. Also taken almost every SSRI, SNRI and tricyclic antidepressant in the book w/ no relief.
For the past couple of years I've been experimenting with self-medication. Here are the drugs I've found helpful:
Stimulants: Propylhexedrine, mephedrone, caffeine, methylone. Use propyl in low doses daily, periodically substituting methylone or mephedrone (never combining them). Stims help me be productive and keep up with my peers, which is a miracle for me. I worry about the health risks of these sketchy drugs constantly but can't seem to justify compromising my quality of life for a longer one...and have had no luck getting a prescription stim despite trying about 7 different doctors.
Opiates: Low-dose poppy tea daily in the evenings. Great for social anxiety, stress and depression.
While I'm physically dependent on poppies, I definitely feel more psychologically addicted to stimulants. The propyl keeps me up way too long and causes me to do obsessive, repetitive things, which can be annoying. Mephedrone and methylone are both shorter acting, though I feel slightly more worried about the heart-related effects with these two. Propyl is better for morning use and productivity, while the other two can be used closer to bed for unwinding or social activity.
Feel free to PM me if you have any more questions!