Anyone here use BPC-157? Any thoughts?

I've used it a time or two to heal injuries with some success. I am in a bodybuilding group and several guys in the group swear by it. There is some debate on whether it works best systemically or locally. I've always used locally, so no input on that.
 
I actually do. Helped a ton with my immune system! After I got Covid 2 times in 2 months I was getting soar throats and strep and the flu at least once a month and eventually after a month of 5 days a week of using it my immune system started to get better and after 3 months I was able to stop because I didn’t need it any more. Thinking about maybe trying it again.
 
I've used it a ton via nasal spray (just not into injecting stuff personally). For soft tissue injury and general recovery I found it great. Now I'm a lazy fuck who barely works out but back in my glory days so to speak I had this recurring tendonitis in one of my achilles, mostly from muay thai probably, all that balancing on the ball(s) of your feet (lol this sentence was funny to write), which I constantly exacerbated from general overtraining.

I remember someone asked a similar question a while back and I reported a specific incident where I went for a long run in icy weather (Wim Hof style, I wore shoes and a t-shirt though, I'm neither that confident nor that reckless, I mean let's be honest you gotta wear shoes if you're running on pavement no matter how calloused the soles of your feet are).. ahem anyway so after I could feel this niggling return of this tendon issue and of course thought ah fuck guess I gotta tone down training for a bit again, but was taking BPC-157 at the time and next day was totally gone. Also helped with DOMS massively, in that I just barely got it at all despite lifting several times a week to the point that during the off-days some urrrrghhh kinda muscular pain was just par for the course, usually.

Y'know as I reflect now I dunno how healthy that intensity of training was overall, is one supposed to get DOMS that often? I'll note I had already seen a physio and been given some basic bodyweight things to do to help with the tendonitis so it wasn't as bad at that point as it had been but was still a kinda semi-regular hindrance which BPC-157 just cleaned up completely.

What I will say about BPC-157 is that I think the jury is still out on the benefits of systemic versus localised administration, I think Ben Greenfield might advocate local injections but (correct me if I'm wrong someone, can't remember if he even says this and I may also be wrong on what I'm about to say) I don't think there's evidence this is necessary versus any old convenient IM or, indeed, nasal spray or even just eating the stuff, I mean it's supposed to be "gastrically stable", doesn't break down in the stomach, can be orally absorbed, etc... but there is a form that is MORE stable somehow and thus probably better for just eating than other ROAs. On the other hand even with strategic concentrations and staggering of sprays to maximise dose, it's basically impossible to get the same kinda dose from nasal administration versus IM, my injuries were perhaps fairly minor in the grand scheme of things and everything I say should be considered in that context.

Ankle sprain though, yeah I mean I'd put that on the same level roughly as what I had so yeah I'd recommend for sure.
 
I've recently started using it subcutaneously this last few days & so far, all my aching niggles (shoulder, knee, upper back) all seem to have diminished, so I'm going to stay with it for now....
 
I'm very interested in knowing more about this. If you see my recent thread on supplements of BJJ/MMA, I train in these arts and I've had a lot of injuries and at 44 my body doesn't recover as quickly as it once did. If this stuff truly does increase recovery time and is relatively safe and doesn't have negative interactions with SSRIs or benzos (I take Klonopin and prozac) then I'd really like to try it.

I've heard that it MIGHT have interactions of some kind with SSRIs, but so far the sites I've checked haven't said anything more.

Has anyone here ever mixed BPC-157 with an SSRI and/or do you know if it's safe or if SSRIs interfere with how BPC works?

Thanks
 
I've used it for injuries successfully. Works well. It's just expensive and temperamental. If the bottle is dropped or shaken too much in transport, the protein chains can break and don't work anymore. And it doesn't last long even if you do store it properly.

I would say if your injury can heal on its own, just do that. If it's a chronic problem that no professional can help, then yeah maybe use it.
 
Foreigner said:
I've used it for injuries successfully. Works well. It's just expensive and temperamental. If the bottle is dropped or shaken too much in transport, the protein chains can break and don't work anymore. And it doesn't last long even if you do store it properly.

I would say if your injury can heal on its own, just do that. If it's a chronic problem that no professional can help, then yeah maybe use it.
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Thanks. Well I just got prescribed naproxen and lidocaine patches for what's bothering me now so I won't use it this time, but do you know if it actually has negative interactions with SSRIs? I hope not because I take prozac and would like this to be something I could potentially take for recovery from martial arts training, but some sites say there's an interaction. Then again, one said BPC 157 is good for preventing serotonin syndrome, which is usually the concern of mixing SSRIs with certain things.

Seems like every drug I want to try I can't because of my prozac, whether it's a psychedelic or something for muscle recovery. I hate it.

Also, do you know anything about Ultimate Methylene Blue? I've heard it's good for injury recovery, but they say not to take it with SSRIs. Do you know if it's actually dangerous to combine with SSRIs and/or doesn't work well with them?
 
Mycophile said:
Thanks. Well I just got prescribed naproxen and lidocaine patches for what's bothering me now so I won't use it this time, but do you know if it actually has negative interactions with SSRIs? I hope not because I take prozac and would like this to be something I could potentially take for recovery from martial arts training, but some sites say there's an interaction. Then again, one said BPC 157 is good for preventing serotonin syndrome, which is usually the concern of mixing SSRIs with certain things.
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I've never heard of BPC 157 interacting with antidepressants, but I guess it's theoretically possible because neurotransmitters are peptides and BPC 157 is a peptide that crosses the blood brain barrier. I unfortunately can't comment strongly on this one.

Mycophile said:
Seems like every drug I want to try I can't because of my prozac, whether it's a psychedelic or something for muscle recovery. I hate it.
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Yes antidepressants are like that. Having taken then myself, I found that they also block potential alternative therapies that can heal the depression. I'm not suggesting you stop your SSRI I'm just saying that I think anything blocking a receptor may prevent that receptor from receiving other healing modalitis.

Mycophile said:
Also, do you know anything about Ultimate Methylene Blue? I've heard it's good for injury recovery, but they say not to take it with SSRIs. Do you know if it's actually dangerous to combine with SSRIs and/or doesn't work well with them?
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How is ultimate methylene blue different from methylene blue?

Anyway... methylene blue acts on mitochdronial energy transport as an antioxidant. Which means it should increase energy efficiency. I personally haven't meddled with it because there are better antioxidants out there. Methylene blue is a dye and I'm not a big fan of ingesting dyes.

That said I don't know enough about it and SSRIs to answer your question. Sorry.
 
Foreigner said:
I've never heard of BPC 157 interacting with antidepressants, but I guess it's theoretically possible because neurotransmitters are peptides and BPC 157 is a peptide that crosses the blood brain barrier. I unfortunately can't comment strongly on this one.



Yes antidepressants are like that. Having taken then myself, I found that they also block potential alternative therapies that can heal the depression. I'm not suggesting you stop your SSRI I'm just saying that I think anything blocking a receptor may prevent that receptor from receiving other healing modalitis.



How is ultimate methylene blue different from methylene blue?

Anyway... methylene blue acts on mitochdronial energy transport as an antioxidant. Which means it should increase energy efficiency. I personally haven't meddled with it because there are better antioxidants out there. Methylene blue is a dye and I'm not a big fan of ingesting dyes.

That said I don't know enough about it and SSRIs to answer your question. Sorry.
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I don't know the difference between ultimate methylene blue and "regular" methylene blue. I had never heard of either till the other day.

What antioxidants do you like for energy efficiency? Do any increase recovery time from injuries?
 
Mycophile said:
I don't know the difference between ultimate methylene blue and "regular" methylene blue. I had never heard of either till the other day.

What antioxidants do you like for energy efficiency? Do any increase recovery time from injuries?
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Too many to list. I really love sulforaphane, quercetin, vitamin E, whole-food vitamin C (not ascorbic acid), and grapeseed extract (not to be confused with grapefruit seed extract). Taking this regularly has a lot of positive effects on my health.
 
The kings of anti oxidant/immune stimulating properties are undenatured whey protein isolate and n-acetyl cysteine
 
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