Mental Health Anybody Else on Agomelatine/Valdoxan for Depression

Rybee

Bluelighter
Joined
May 29, 2013
Messages
1,305
Hey Guys,

Just wondering whether anybody else is on Agomelatine/Valdoxan for depression? I'm currently taking 50mg and it's worked wonders for me in the last 3 months. Back in July I was in a very dark, dark place and to say I owe my life to Agomelatine is probably no exaggeration.

Just wondered whether there's been any other success stories, or otherwise. It's quite a novel drug in the treatment of depression and I've suffered zero side effects from it. Other than the cost (not available on NHS), it's been great to me!

Rybee
 
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I was prescribed and used Valdoxan from December last year to June this year, 25 mg /day. I didn't experience any side effects, but helped very little for my depression and anxiety. Changed from Valdoxan to Remeron in June, starting at 15mg, upped the dose to 30 mg after a month, and eventually to 45mg in August. It helped a lot with my sleeping problems, but not so much for the depressive symptoms. Added Wellbutrin 150mg in September, and wow, what a difference! I feel much better now, more motivation, and better concentration.

I also take Temgesic for pain, diazepam for anxiety, and melatonin (Circadin 2mg XR tabs x1) + Zopiclone (7.5mg x2) for sleep.

Have been on 10+ antidepressants, but none of them have worked, until I got the Remeron + Wellbutrin combo. I can definitely recommend it for hard to treat depressions!

Good to hear that the Valdoxan worked for you :)
 
Valdoxan was a weird med for me... it was like it switched off my internal daytime/nighttime regulator. Body didn't know when to wake up... when I was awake I felt like it was nighttime even though it was sunny outside. I could seriously sleep for 22 hours on that stuff. I'd wake up at random times, get up all sluggish, eat something, go to the loo and then go back to bed after 2-3 hours awake. If I'd look outside and see it's daylight and birds were singing I'd be a bit confused as it felt my body clock was permanently stuck at 3am. I have very little memory of my time on valdoxan... not because of amnesia but because honestly, I was a moonwalking sloth and did nothing. I was so out of it I wasn't even depressed, nothing happening in the head, just basic zombie instincts... sleep, eat, excrete, hibernate.
 
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