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alprazolam vs clonazepam

G

gaga11

Bluelighter
Joined
Apr 19, 2010
Messages
175
okay so honestly i take clonazepamin case of emergencies cause i usually cant sleep but i got some drops prescribed dose of 2.5 mg/ml do not wanna get hooked so stopped doing it for a week until yesterday i was feeling like shit my gums hurt and i also have some an 8 cm ovarian cyst sorry if this is so graphleic..anyways i took it to sleep about 7 drops but t also mixed them with water ..so the point is i only got to sleep from about 1 am until 630 pm to go to school today at school i wa sin a good mood i mena laughing and all my personality was cool but pshysically i felt like CRAP i mean nipples were sore and im teething one of my wisdom teeth is comign out so my gum is likee EXTREEMELY sore maybe that also provoked the insomnia..it tired valerian during the week i decided to stop clonazepam..wouldnt do anything so anyways i was feeling rlly rlly bad as int ired dizzy weak ha the chills abdomen pain maybe i have some dehydration not quite sure and the cyst issues since my period is late although i am absolutely not pregnant so i took .50 mg og alzaprolam about 30 mins ago and i am feleing extremely great and happy like i could sleep but i dont want to since i feel rlly good both physically an dmentally my mind is much clearer this is so weird,,,o mean when i wa son clonazepam i would sometimes cry out of the bblue
what do u guys think? i also do not wanna get hooked on clon but i could use it recreationally during bad days i dont like the fact of using benzos on a daily basis because withdrawal scared the shit out me but i feel good after been struggling for about a week with health issues and this is just bizarre...i will have the cyst removed soone ror later but it doesnt concern me anymore..by the record im not high just got some mind clarity and my body no longer aches
 
post correction about recreational use i meant alprazolam since clonazepam just makes me feel wired and stupid...i will stop using it once my meds run out and only borrow clonies or alzprazolam from friends.god knows how i will sleep
 
Clonazepam can have paradoxical effects and cause some people to feel agitated, emotional & moody which may be why it makes you cry out of the blue. It can also be quite sedating, making you feel stupid. If alprazolam works better for you than just take that as needed rather than the Clonazepam. People have preferences. Alprazolam is less sedating which may be why it makes you think clearer.
 
u might be right..it makes me feel really good like it also helps me feel less depressed and like i woeey less about my problemas i might just switch medications
only bad thign about alprazolam is it makes me feel a bit euphoric like super euphoric contrarly of clonazepam which make sme feel totally retarted and depressed
 
I have been on alprazolam for 4 years now. I'm up to 1 mg 3x daily right now. It is an absolutely amazing anxiolytic, but its other benzo effects of muscle relaxation, sedation, anticonvulsion, and amnesia are mediocre at best.

I prefer alprazolam to clonazepam because I think it is the better anxiolytic overall and it has a faster onset of action. But overall, clonazepam is the more useful benzo. It lasts longer. It has better muscle relaxant properties and is a much more powerful anticonvulsant. As far as sedation goes, I find they are both similarly lacking in that department - which is alright because they are anxiolytics meant for daytime usage. Amnesia wise, I think they are similar - but I think alprazolam is definitely the more amnesic of the 2 (afterall, alprazolam is a triazolo benzo and that family is known for causing amnesia).

Addiction wise, alprazolam is the more addictive one - at least its more physically addictive as it is a short acting benzo. Short acting benzo's are always more physically addictive than long-acting ones. Alprazolam will be much more difficult to come off of, so be wary!
Psychologically, it all depends on which one you prefer or makes you feel "good". For me neither are euphoric. But I find temazepam to be very euphoric, but that is an hypnotic which you will not get for anxiety.

This is my experience with them, anyway.
 
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really i tend to remember all of my benzo expieriences always with alprazolam but not with clonazepam like one time i just woke up in my bed but i remembe ri wasnt in my room like i wa sint he kitchen it gave me a slight blackout but i have never suffered from blackouts from either of these drugs only problem is when i stop taking them like when im sober during i random day i will try to remember my expieriences and they seem kinda blurry but this doesnt happen all the time like one time i mixed clonazepam weed and some booze and to this day i remember every vivid detail i guess it depends on many factors like the tolerance dosage your mood your memory...mine used to be good now its actually failing im considering ginki biloba for my own sake like todya i felt absolutely stupid at school i swore somethign was wrong with me but now i feel just fine
 
kokaino said:
Addiction wise, alprazolam is the more addictive one - at least its more physically addictive as it is a short acting benzo. Short acting benzo's are always more physically addictive than long-acting ones. Alprazolam will be much more difficult to come off of, so be wary!
Psychologically, it all depends on which one you prefer or makes you feel "good". For me neither are euphoric. But I find temazepam to be very euphoric, but that is an hypnotic which you will not get for anxiety.

This is my experience with them, anyway.
Click to expand...

All benzodiazepines are all just as physically addicting. Same symptoms, all just as bad. Only difference with alprazolam is that physical symptoms kick in much quicker because of its short half-life. This makes the symptoms feel worse. For instance if you are addicted to Diazepam, you could stop taking them for like 3 or 4 days before you start feeling symptoms. While with alprazolam, if you are addicted, symptoms can kick in just after one day of abstinence. Just missing a couple doses and you can start to feel bad.
 
K'd-OUT-in-AZ said:
All benzodiazepines are all just as physically addicting. Same symptoms, all just as bad. Only difference with alprazolam is that physical symptoms kick in much quicker because of its short half-life. This makes the symptoms feel worse. For instance if you are addicted to Diazepam, you could stop taking them for like 3 or 4 days before you start feeling symptoms. While with alprazolam, if you are addicted, symptoms can kick in just after one day of abstinence. Just missing a couple doses and you can start to feel bad.
Click to expand...

No that's not true. All benzos are not all equally physically addicting. Yes, with the short-acting ones the withdrawals kick in quicker and are more severe and with the longer-acting ones the withdrawals take longer to kick in and are less severe. But there is a specific receptor responsible for physical addiction that some benzo's have higher activity at then others.

Benzodiazepines with an high affinity to the γ2 subtype are more physically addictive than others. Benzos with high affinity to the γ2 subtype are: temazepam, brotizolam, triazolam, alprazolam, lorazepam, loprazolam, midazolam, flunitrazepam, clonazepam, lormetazepam, flutoprazepam, nitrazepam, nimetazepam, and estazolam.

All other benzos have mild to moderate affinity to this subtype, meaning they are less physically addictive. Included in here are chlordiazepoxide, diazepam, flurazepam (partial agonist), oxazepam, prazepam, quazepam (highly selective to alpha1 subtype, but with weak affinity), and other similar benzos.

Typically, the hypnotics are the ones that have a very high activity at this subtype. So not all the benzos that have a very high affinity to the γ2 subtype are listed. These are the ones we know of, but there are other hypnotics like cinolazepam, doxefazepam, and haloxazolam and many other probably.


Have you also heard of the β3 subtype?
 
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Yes, I have heard of all the subtypes of benzodiazepines. Benzodiazepines with high affinity to the β3 subtype are generally the hypnotics. But to what you are saying, I have never heard that affinity to the γ2 subtype dictates the severity of physical withdrawal symptoms. If you could provide a link that would be awesome but to this day I have never heard of this.
 
memory wise how can i improve my memory i mean i have a great memory but since i started taking clonazepam it has been worse i even stopped takign it during a week and i jsut dont feel any excitment or memory do u guys know why and how cna i improve these
perhaps omega 3 or ginki biloba
also is it short term or long term memory loss once u stop takingbenzos
any advice would be appreciated
 
The severity of long term memory loss is dependent upon how often and how long you use benzodiazepines. Short term memory loss will generally go away once you stop using.

I completely understand what you are talking about, I have quit over 11 years of daily use and have forgotten so many things I'll never remember. I will still suffer symptoms of short term memory loss. After I've quit I still forget things easily. I also know what you mean about the inability to feel excitement. I was switched onto a new similar medication called Lyrica to get off the benzos and still experience it. This won't go away until you are fully off of them.
 
yes i mean i still remember some thigns fromt he past but not as vividly a si used to i mean before i ever tried benzos..but i feel trapped like when i take clonazepam i rlly forget lots of stuff that will take a hard time for me to remember
i hope this is short term loss..cuz it oculd be hell to lose your memory long term wise like forget things about your childhood is this even possible..it would suck i thing im gonna cut off the benzos and use something sort of like melatonin to sleep theyre starting to scare me i mean i might only use themr ecreationally
do u know any memory drugS?
i also do not eat well usually maybe thats part of why ive forgotten stuff
 
K'd-OUT-in-AZ said:
Yes, I have heard of all the subtypes of benzodiazepines. Benzodiazepines with high affinity to the β3 subtype are generally the hypnotics. But to what you are saying, I have never heard that affinity to the γ2 subtype dictates the severity of physical withdrawal symptoms. If you could provide a link that would be awesome but to this day I have never heard of this.
Click to expand...

That's right! The hypnotic benzos usually have very high activity at the β3 subtype, but even within the ones that have high activity at β3 subtype there are differences among them. They all have high activity, but some have higher than others. The β3 subtype also happens to be a barbiturate receptor and modulation of that subtype is associated with anticonvulsive action, sedation, muscle relaxation, various other reactions related to respiration (much similar to the α1 subtype, the respiratory action here is more serious). Modulation of the α1 subtype is also associated with respiratory depression, so with the hypnotics it's a double effect on respiration. This is the reason why there are vast differences in their fatal toxicity indices, even within the hypnotics themselves.

Temazepam as we know is the most toxic benzo with a fatal toxicity index of 11.9 (95% confidence interval 10.9-12.8 range). In the British study, this trumped all other benzos (which included alprazolam, triazolam, flunitrazepam, nitrazepam, oxazepam, lorazepam, diazepam, chlodiazepoxide, clonazepam, and bromazepam). Temazepam's 11.9 rate is above that of some tricyclic antidepressants and approximately equal to that of some barbiturates. So as far as benzo's go, it's very high. In contrast, oxazepam had a rate of 2.3 (1.2-3.4 range), and the rate for all benzodiazepines combined was 5.7 (the average for benzos). Further studies in Britain, Australia, Ireland, and a few other countries all corroborated the results of the original British study: temazepam was the most toxic benzodiazepine by far.

Obviously, this is due to the very high affinity to the γ2 subtype, β3 subtype, and of course the α1 subtype receptors. Nitrazepam, flunitrazepam, and triazolam have shown similar toxicity, but to a lesser degree. In Australia, nitrazepam's death rate due to overdose is high, lower than temazepam, but second to it.

You can check out this thread I posted and it has the source there.
 
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I've used clonazepam and alprazolam both.clonazepam upto 2mg and alprazolam upto 0.5mg.
I didn't find any benefit from clona and alprazolam was better for me.i use 0.25 alprazolam for good sleep and for stress relief occasionally and 0.5mg as muscle relaxant,when i need rest too.
0.5 alpra makes me somewhat sedated+some memory problem+sleep paralysis but 0.25 doesn't causes any side effects to me.i take benzo occasionally only.I don't use it for inducing sleep bcoz it doesn't help me in that manner.alpra also give me music euphoria and sometimes it helps me in getting ideas/clear thoughts(weird).sometimes when i take alpra i don't need to sleep.alpra kick in within 30mins for me.
 
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alprazolam is really good if you are having a panic attack and need immediate relief and not as good for everyday use if you need to use a benzo everyday imo.

clonazepam is great if you need a benzo daily because of it's long half life, I take it daily and I don't notice any side effects unless I accidentally take too much or don't take it. It wipes out my anxiety and eliminated my need for alprazolam.

so, they're both good depending on what you need them for, besides everyone reacts differently to these things, alprazolam actually messes with my thinking more than clonazepam, but alprazolam has an antidepressant effect that clonazepam lacks. xanax was like benzo crack for me, clonazepam is much easier to take as prescribed without needing to raise the dose imo.
 
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