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Agmatine sulfate for opiate/opioid withdrawal

H

Halif2

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Hi everyone. I am a semi-longterm opiate addict. Around 15 years off and on (mostly on).

I'm always trying to fight the good fight. Detoxed more times than I can count but can't quite seem to let it go.

Anyhow, I'm curious if anyone else has had any experience with the amino acid (?) mentioned in the subject line. I think it actually helps with the progress of jumping off. Please understand that if you're in deep you need to set your expectations to... low. But this, loperamide, and magnesium are the only things I've ever found to make any difference. When I jump from a few years of daily use it doesn't exactly make the biggest difference, but honestly I don't think anything will.

However, if you've relapsed and you want off again, this may help. Just trying to provide something useful in the way of harm reduction.

Be well, all of you.
 
daturetard said:
https://www.nature.com/articles/npp200956 this one has something about meantime, another nmda antagonist
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541583/ dxm mentioned in here
It makes sense that it would help with wds because of nmda antagonism, but I can't find a study (with a few seconds of looking) mentioning agmatine specifically.
Click to expand...

Thanks for that info. There is very little in the way of information directly related to agmatine out there. Even anecdotal accounts are sparse.

I gave it a go because it seemed benign and because I'll try anything to help WDs. What I found was a decrease in the hot/cold temperature madness and, most notably, less despair than usual. That latter one was the reason I made this post, because I have found that aspect more challenging than any of the physical ones (yes, even more than RLS).

I'm cautiously optimistic about its potential as part of a detox toolkit. However, I really want to stress that this is just a personal experience and also that it did not in any way remove the symptoms. Sweats, RLS, insomnia, anxiety, and all the rest were still there, but crucially some of those things were lessened.

If you're in a situation where, despite having all the best intentions and motivation in the world, you just cannot see it through to the end, this little push may help some of you.
 
Glad it helped you some. What are you detoxing from and what dose? I have never minded RLS as a symptom too much, unless its when im trying to sleep, but I have a friend who has it constantly because he's on antipsychotics and has tarditive diskinesea (spelling?).
 
iv been experimenting with agmatine, not sure it does a lot for me

have u thought about low dose dxm? less than 50mg dxm a day
 
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