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Stimulants Affect on serotonin

Youngling

Bluelighter
Joined
Jan 25, 2013
Messages
104
Location
6 feet under
Amps (not meth) are said to affect serotonin at "higher doses". At what dose would you say this occurs for a normal/average person?
 
the ec50 for serotonin release is about 10-20 times higher than the ec50 for norepinephrine release for dextroamphetamine

as a general rule though, amphetamine is not clinically relevant as a serotonin releaser. amphetamines, the whole class of drugs, have effects across the board wrt serotonin release. the ring-substituted amphetamines and methamphetamine are much more potent serotonin releasers than d-amp is.
 
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