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  • Trip Reports Moderator: Cheshire_Kat

5-MeO-PiPT (6mg orally over an hour / 1st time) - "Trial Run"

Pfafffed

Bluelight Crew
Joined
Jun 30, 2015
Messages
1,829
SUMMARY:

Initial impressions of 5-MeO-PiPT are that so far it seems to me like it's no more potent than 5-MeO-MiPT. It might be less potent, time will tell. I took 2mg, then after 35min took 2mg again, then again after twenty minutes. The time to onset and to full effects from each dose was remarkably fast on a completely empty stomach. I don't know if I ever made it past a strong + into a ++ or not. If I did, then the effects were mostly indistinguishable from 5-MeO-MiPT. I think when tolerance goes down, I'll try it again starting at 6mg all at once and adjust up from there. Because the overall dose was low and split up over a long period of time, I don't think there's much that you can really take away from the rest of the report.

It was a little tenser and crampier than 5-MeO-MiPT, more along the lines of 4-HO-DiPT (and probably 5-MeO-DiPT, but I wouldn't know.) It didn't have the richness, empathy, appetite enhancement, or general satisfying feeling of life-experience enhancement of 5-MeO-MiPT. The somatic sensations might have been great at a higher dose. The libido enhancement wasn't there after the onset, and it generally felt a little dreamy and a little neutral. All of this is probably due to the low dose and the ROA, which was expected. I expect that it will have a lot more character at a higher dose, but given the complete lack of history of human use, I wanted to start low and slow. Frankly, I should have started lower and slower, and I just got lucky that the dosage of this drug was consistent with all of its close relatives. I enjoyed the onset and the peak, and I think I will enjoy this material even more at a proper dose. I doubt that it will end up being something that I'll have a place for given my affection for 5-MeO-MiPT, though. I will be interested to try vaping it at some point--maybe it will show more of its character that way.

BACKGROUND:


I have experience with sixty or more different psychedelic compounds over the last few decades.

SET & SETTING:

I slept for ten hours the night before, four hours of it were really restless and broken, with a constantly repeating dream about taking this drug. I'm guessing it was anxiety, since I couldn't find any information about people having taken it before. My sleep from 1am-7am was deep and restful, though, and I woke feeling fine but groggy. I had some ashwagandha, a strong matcha latte, and an iced coffee over the course of the next few hours. This eventually perked me up enough to go run some errands. I forgot to have breakfast due to the milky latte. Due to a half a glass of wine and 800mg kratom, I felt a little bit crappy by 10am and my bowels weren't happy with me. Neither alcohol nor kratom sit well with me any more.

REPORT:


10:10 I dissolve 10mg of the material sold as 5-MeO-PiPT in 1mL 95% ethanol. It dissolves readily. I measure out 2mL (2mg) and hold it under my tongue for least five seconds pass before I get some water to swallow. My stomach is still empty. I'm anticipating 40min to comeup, so I'll be waiting to see how this goes before re-dosing.

10:17 - 1st alert. Within minutes, the effects grow noticeably. This is unexpected. 5-MeO-MiPT usually comes on within 30min to just over an hour, averaging 40 minutes. I wonder if this has to do with the ROA, with the ethanol making it more available sublingually, so I got a faster onset. It doesn't seem likely.

10:30 - The effects are barely distinctive yet, with the sudden ramp up slowing down considerably, but still growing. It's mostly marked by some pleasant stimulation and a feeling of that 5-MeO-MiPT warmth and a hint of grit and muscle tightness. The crappy feeling that I had had from the tiny hangover from last night's amount of kratom and alcohol has been replaced with a good somatic feeling. There's a hint of tremoriness present, but it's faint. A brief and surprising bit of possibly placebo color shift manifested. I feel more vital, too, suggesting some erotic enhancement. I think I could be content at this dose, or even see microdosing this. I have a bit of chest tightness, but I've had that lately regardless.

10:45 - I'm take another 2mg at the +0:35min point. I can tell by my cold hands and feet that my blood sugar is low; I will need to figure out something to eat soonish. I'm getting a little shivery rush of euphoria up my spine and the front sides of my torso, as well as a little bit more muscle tightness. So far, I quite like this material, definitely more than 4-HO-PiPT.

10:51 - I feel the onset of the booster dose.

11:10 - I'm debating taking a final booster. It's far too early--I should wait another twenty minutes--but I'm getting quite hungry. Not a lot has happened since the last update. I'm at a pleasant +.

11:15 - I take another 2mg and go make a peanut butter and jelly sandwich. And some magnesium to head off muscle tension.

11:30 - Starting to come up on the third dose. I don't think I could tell this apart from 5-MeO-MiPT in a blind test at this stage. Maybe just through muscle tension. Appetite was unaffected--I ate a half a PB&J with a cup of a milk and a banana. It wasn't any better or worse than usual. The space is feeling more generic now, possibly due to the staggered dosing. If this is bi-phasic like 5-MeO-MiPT, I hope that this staggering doesn't lock me in to the first stage for the whole experience as people report with 5-MeO-MiPT.

11:40 - The headspace is stronger headspace now, but it's still pretty clear. The somatic feelings are really subtle, but I think they would be quite pleasurable at a higher dosage. There's zero visual activity to speak of.

11:55 - I just used some nitrous. I became aware of how much less pleasurable it has been lately compared to how it was years ago. The same is true for alcohol. This made me think that as people have said all through history, youth is wasted on the young. The pleasures of life exist in a gradient, and wick away as we age, leaving less there for us to enjoy as that space is occupied by an increasingly burdensome aches and pains of a slowly failing body. Bleak as this is, it's also an affirmation to throw myself fully into enjoying the moment, because postponing present happiness for a payoff in the future by this logic seems doomed. I'm aware that these thoughts are nitrous inflected, and that I may discard them as invalid when the effects wear off.

1:00 - I'm solidly in the plateau now I must conclude, as I've been thinking for some time. What a shame--I don't think this is going to progress anywhere interesting. I knew that was what I had hoped for setting out today, aiming to underdose but get a feel for what a proper active dose may be, but it's still a bummer. I got to a strong + or maybe a ++ during this experience, and it was quite pleasant. It seemed more clearheaded than 5-MeO-MiPT. It lacked the visuals, the enhancement, the empathy, the hunger. The non-descript character is likely a product of the low, staggered dose. I think next time I will start at 6mg all at once, then titrate up. I have 4mg still sitting out, but I'm sure that all it would do now is extend the duration. Far from being an annoying hanger-on space, this place seems nice enough. I just have to come to terms with the fact that the rest of the experience is probably not going anywhere interesting.

It turned out that sex was not enhanced in terms of somatic sensations or emotional qualities. My desire was not any higher than normal during the plateau, maybe even a tiny bit lower, but I had not trouble getting or maintaining an erection. The neutral libido contrasted with how I was feeling earlier in the experience. I was at least more mentally present during sex, which made it more satisfying than when sober. Orgasm felt normal. All this again is likely due to dose and due to the fact that I'm already mid-plateau.

1:40 - My friend and I just got back from a half an hour walk. It was a beautiful day outside, which was nice. There was nothing really of note that happened. I would have enjoyed it more if my guts hadn't been a little gas-crampy.

2:00 - I have a little bit of a libido again as this very slowly wears off.

2:26 - After finally farting, my gas cramps subsided. I had a second orgasm, and am now noticing that I'm a little hungry. The effects seem to be waning even more now.

3:00 - Made some salad and a frozen pizza, which was manageable both to eat and prepare. Noteworthy in that it wasn't noteworthy--eating is usually a chore for me on most non-MiPT family psychedelics.

4:00 - Still not entirely at baseline. I've been yawning a fair bit for an hour. Some 4C-D sounds nice, but who the hell know what drug interactions there are with this one. I don't anticipate any, but 5-MeO-DMT and 5-MeO-aMT both interact weirdly, so I'm playing it safe. I would normally avoid mixing to see what the true duration of the material is, but I think I hosed that with the staggered dosing anyway. I think I'll just make some green tea, maybe some phenibut.

5:00 - The headspace is still remarkably stable. I'm still far from down. The farting at least has stopped. This is about seven hours from when I initially dosed, and I'm sober enough to start working on chores around the house, but not sober enough to want to. I hope that future experiences have a little more richness and character to their plateaus. I expect they will. If not, I could see vaping this instead of taking it orally to maximize the positives and reduce the duration.

Tagged by Xorkoth
substancecode_5meopipt
substancecode_tryptamines
explevel_firsttime
explevel_secondtime
exptype_positive
roacode_oral
 
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Awesome, thank you for this. I eagerly await to see how a proper dose taken all at once works out.

Im a big of fan of 5-Meo-mipt so I reallly appreciate this report. Hopefully this one is also a gem
 
Update: possibly botched second trial

tl;dr I took 6mg of 5-MeO-PiPT and pretty much all it did was make me feel warm, sweaty and weird. Thought that it was a dud, but on reflection it may have been a drug interaction.

Over the last 12months, I've had only two bouts of depression that have cropped up. One was last week. On Sunday, I took 20mg of tetrahydroharmine sublingually, which abolished it for that day. It crept back in, so I ended up taking SJW on and off throughout the week. It proved persistent, so on Friday, I took 20mg of THH again on top of my 3x tablets of SJW. This sorted me out again.

~18hrs later, I didn't feel any effects from the THH or SJW, and decided that I would take some 5-MeO-PiPT. I don't think the mechanism of action for SJW is well-understood, so I wasn't especially worried about it. I had cautiously used it in reasonably close proximity with psychedelics before, and I never noticed anything. Novel 5-MeO-substituted tryptamines are always a worry when it comes to serotonergic drugs, but I recklessly decided that enough time had elapsed between doses. I knew that THH wasn't supposed to be an MAOi and that it was supposed to be a SSRI (but was skeptical that it would actually prove to be in vivo.)

Long story short, I took 6mg of 5-MeO-PiPT and it didn't do much other than make me feel warm, sweaty, and weird. Despite taking the entire staggered oral dose of my first experience at once, the effects were much, much less psychedelic. The duration was also dramatically shortened to what seemed like 4hrs tops. Apart from some very mild cognitive effects (and no visuals,) my experience was mostly marked by a weird feeling that I associate more with serotonin releasers, reuptake inhibitors, and the like. I'm weird--drugs that increase synaptic serotonin levels don't do what they're supposed to when I take them. MDMA makes me feel detached and melancholy, 5-MAPB makes me feel stoned and dumb, 6-APDB makes me feel bored and blunted, and RIMAs make me feel dumb. Same goes for SAM-e, and the list goes on. This felt sort of in that vein, a sort-of somatic feeling of emotional pain or longing, maybe even desire. Mostly, I just felt warm and sweaty, a little numb and a little tremory. All of these suggest that there may have been something more than just 5-HT partial agonism going on, but the evidence for that is really weak. I just say this to suggest that to be on the safe side, it might be best to try and avoid taking 5-MeO-PiPT in close proximity to MAO inhibitors, SSRIs, RIMAs, and the like. It's a bit of a no-brainer, but you never know. I should have been more careful.

What I think is pretty odd about the whole thing is that the effects were so blunted. I don't think I could even call this a second trial--it just didn't feel like much at all. What I did feel was pleasant enough, but it was really single dimensional and quite strong in that one dimension, enough that I decided not to proceed with the plan to bump up the dose by 1-2mg as I had intended. I've never taken a psychedelic while on an SSRI, but I wonder if that's what it's like, almost like there's a drug trying to beat down the door to get in, but all it's doing is making a lot of annoying noise.
 
Well, there's a good chance that there may have been no interaction at all, that the 5-MeO-PiPT is a dud. If there was an interaction, though, I'm not surprised that it didn't make it stronger. THH is supposed to be an SSRI (which blunt psychedelics,) not a MAOi (which can potentiate some psychedelics.) Who the hell knows that St. John's Wort is; some reports suggest it may have SSRI activity, but I haven't read anything that gives me any confidence that the author has a good understanding of its pharmacology.
 
5-MeO-MIPT is my favorite chemical, bar non, but only for one purpose - sex. I found it to be far superior for this purpose than even 2C-B, because unlike 2C-B, when taken in doses of 3-5mg, its psychedelic aspects don't distract one from sexual activity. And it has been a while since I saw anybody selling it, which makes me worried. I tried 5-Meo-DIPT a couple of times, but found it to be overstimulating. 5-MeO-EIPT was actually a great sexual enhancer that added just a tiny, pleasant amount of edginess to 5-Meo-MIPT type experience, but unfortunately it was on the market for a very short time. I know that US government tried to ban 5-MeO-MIPT this year, but got sued and backed off. Yet, nobody is selling it. What is going on? So when I saw 5-MeO-PiPT, I had high hopes.
 
i found 5meo-met better than 5meo-mipt which i quite liked, too. how does 5meo-pipt compare to 5meo-dpt? 5meo-dipt i found to be a bit lackluster.
 
Third time lucky. Much nicer. Might still want a higher dose.

 
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