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5-HTP + Vitamin B6???

Bare_head

Bare_head

Bluelighter
Joined
Jun 7, 2005
Messages
3,051
Location
UK
What complications are there when taking 5-HTP with Vitamin B6?

I have heard that the 5-HTP is useless when taken with vitamin B6 is this true or just to a certain extent?
 
Try using the search engine next time. But to sum it up:

5-HTP is converted to serotonin in the body. Not limited to the brain, but the gut, liver, blood stream etc...

Free serotonin in the blood is bad for you, activated peripheral 5-HT2B (serotonin) receptors is what made diet pills cardiotoxic.

B6 is a co-factor in the metabolism of 5-HTP to serotonin.

Taking more B6 increases the rate of this reaction. It will probably increase the reaction most in the gut, 2ndly in the liver, 3rdly in the blood and last in the brain (i.e. the order in which the vitamin is absorbed and distributed).

Therefore, taking B6 with 5-HTP increases the amount of 5-HTP converted to serotonin outside the brain (i.e. gut, liver and blood). This is bad. It could just mean you waste the 5-HTP, and are more likely to get gastrointestinal side effects... however, it could also be bad for your heart.

No one knows the answer to these maybes.

Conclusion: There is no advantage to taking 5-HTP with B6
 
yeah dude i take a b complex vitamin when i take my htp cus its supposed to help metabolize the htp into seratonin better not the other way around
 
Is there any suppliments combined with 5HTP that will increase the amount of serotonin that's sent to the brain?
 
yes its called serotone, it has B6 also included to speed rate of reaction, yet they ignore research that states taking 5-HTP with b6 will cause damage to the heart
 
There aren't any supplements I can think of Sleaze, there are prescription only compounds that might help, but no supplements spring to mind.
 
Why then in the UK do most 5-htp suppliments come with Vitamin B6 (and B12 and other bits and bobs, too)?
 
I'm damn glad I read this post. Until recently, I was taking 5htp pills with B6 during the week after going out. It seemed to help even me out over the next week but now that I know this I won't use it anymore.
 
^^ Because the supplement/vitamin/herbal industry is completely bullshit and lives almost entirely off psuedo-science.
 
^ disgruntled ex Holland and Barrett employee? :)

I'm not as mad as some people about suppliments (have seen some truely scary posts from obsessed people in Yahoo groups)... But two things come to mind...

One - This is one (forum of a) site that recommends 5-htp and Alpha-Lipoic Acid (and other anti-oxidants) quite often (as would I),

Two - I have two groups of mates who I go out with, one group has a multivit a day, and plenty of 5-htp after being out, and one that doesn't. There is a stark contrast on the day(s) after, one set of us glows, and the other wants to commit suicide. I'm in the lucky group :)

Bit of a ramble here... anyway, thanks for the heads up :)
 
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