5-htp affecting rolling.

[Fine wine]

I'm thinking of taking 5-htp on a daily basis but I have a few questions. There are so many contradictions about it on bluelight, particularly in the older posts from the year 2000. From some of the information I've seen on bluelight it seems that 5-htp should only be used for post loading. This leads me to my first question. Will taking 75mg of 5-htp daily reduce the quality of my rolls?
If it will reduce the intensity of my rolls then how many days before rolling should I stop using 5-htp in order to get the best possible roll? Have I totally misunderstood all the information here and do I need to go back to school and learn basic English?

Thanks in advance.

 

[Tarsarlan]

I believe the general concensus is that it will possibly reduce the quality of your roll if you take it a few hours before dropping. If you take the 5htp in the morning then you will be fine... When I pre-load, I take the 5htp the night before and that always gives my roll a little boost...

 

[babydoc_vic]

I recently used 5htp for the first time. The week before the roll my hubby and I both took 50mg for a few nights then 100mg. We had the last dose the night before the roll. That night we took 1 007 each. Now the last time we had these babies (which test purple-black on EZ2) we had a great roll for maybe 3 or 4 hours. This time we thought we might go another half after the whole. Well, there was no need. We were rolling so hard we had to sit down for the first hour. We actually rolled a bit too hard - we couldn't dance for a while which was a bummer. We post-loaded with 150mg about 10 -12 hours later (after a sleep)- I was worried if we did it on the comedown we might comeup again. I have read warnings to this effect on other sites. We continued with 150mg for two days, then 100mg, then 50mg for a few days. I should also note that we had some grapefruit juice before the roll, which may have further intensified it.
[This message has been edited by babydoc_vic (edited 20 July 2001).]

 

[Darkblade]

I found that after loading with 100mg of 5HTP a few hours ahead I get a more intense roll. I hadn't pilled for about 3 months and I recently had the 5HTP and then a few hours later dropped 1.5 HQ's .I was rollign so hard I had to go lay down. After about 5 mins I was OK, just the peak hit me like nothing ever has before. After that everything was amazing. Almost as good as the first time I did it 5 years back.

 

[Fine wine]

Looks like this will be a good thing. I just had to clarify it though. Thanks for the responses.

 

[NHL Guy]

Hmmm... that MAY be the 'general concensus' but it certainly is not the case in my experience. I see NO benefit in using 5HTP on a regular supplemental basis and I find beliefs that an IMMEDIATE-PREloading with 5HTP will reduce the quality of your 'roll' unfounded. This is the first ive eva heard of the theory.
I myself, like Darkblade, find that a 100mgs approx three hours (usually with my last food intake) prior to 'drop-oclock' gives me the BEST pill experiences ive eva had. In laymens terms: your brain has the building blocks to make fuckloads of 5HTM all night without getting AS depleted as it would do operating the same synthesis on its own natural manufacturing ability. Hence little, or no comedown anxiety, reduce 'scatteredness' immediately following, and the minimisation of Tuesday Blues(personally my body reacts faster, I get these symptoms on a sunday nite/monday day. Based on a friday nite MDMA usage.)
Post loading with another 100mgs on sunday night (again based on friday nite pilling) will help eliminate these symptoms of slightly reduced levels Seretonin synthesis due to 'neuron' regeneration.
BUT, based on a wide variety of 5HTP research ive done, repeatedly loading with more than 100mgs within each 24hr period, can result in toxic levels of seretonin synthesis, the reason for this is of course that 5HTP crosses the Blood-Brain barrier with ease and as such is not effeciently regulated by the brain to control seretonin production. This is major contributing factor in the possible contraction/onset of Seretonin Syndrome(look this up... there are other threads relating to this specifically.. it CAN be dangerous even fatal in extreme cases if you dont know this already look it up for yourself)
If you use anti-biotics(eg. Amoxicillin) more than ABSOLUTLEY HAVE TO, your body 'learns' to run at base level using the medication as well. Much the same as a 'tolerance'. This is the same with your brain chemistry also.
In this reasoning I do NOT take 5HTP as a 'daily' (or even Bi-daily) routine... I DO however find that letting my brain run 'on its own steam' during the week but Pre loading 100mgs, DROPPING, DANCING THE NIGHT AWAY, SLEEPING, then Post loading 50mgs to overt 'midweek blues' has its benefits and MOST certainly DOES give a BETTER peak, a much more loved up 'roll', and a smoother week ahead.
In the meantime, as a 'daily routine', I prefer to ingest other forms of Tryptophan that can be regulated into seretonin synthesis on a more stable basis. ie.EAT GOOD TRYPTOPHAN RICH FOODS.
But everyone to their own, I'm illustrating the practicality of what I choose to summise from other people's official 5HTP research... always wise I think.
=K9=
~~~~~~~~~~~~~~~~~~~~~~~~
Lets go jumping over board, into waves of joy and clarity.
A fallen angel walked on the sea.
And I'm playing in the shallow water, laughing while the mad dog sleeps.
And I cant look up, fingers of love move down.
And I cant look back, fingers of love move everywhere. -N.Finn
~~~~~~~~~~~~~~~~~~~~~~

 

[robE]

hey k9, and everyone...
im about to try taking 5-htp ive read everything about the problems of how you can be damaged from low seretonin and high dopamine. Eg dopamine being wrongly reuptaken and broken down into peroxide. I try to take to postload antioxidants and take multivitamins basically everyday to help reduce this.
Anyway yeah, i thought i might try 5htp. But can anyone tell me a good place to order it from? im in sydney, australia. I can use my credit card. And how much am i expecting to pay.
Also should i be taking 100mgs to pre-load on my last night before a night out? then postload about 50ms for the next couple days?
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Yeah nice one brov!

 

[ful_sik_trippa]

Thanks for the info K9, i was a bit confused as to how much and when to take 5HTP. My rolls havent been as good lately, and i have been quite down for the next couple of days. Im going to order in my first trial of 5HTP this week from the US.
8)

 

[bradan]

Personally i cant recommend 5htp enough,post and pre load..I've even dropped some in a peak and it seemed to bring the peak back hours later..i've even had the same pills twice once with a pre load and once without and found the pill to be twice as powerful as the one before..one capsule of what i thought was weak mda turned out to be another completely different experience again after using 5htp..
Vitaminsaustralia sell 5htp .its only 75mgs and comes with other stuff like magnesium..personal i prefer the 100mg stuff i get from the states from vitaglo..it works out to be about 50 cents aust per gel cap which is a cheap answer to a fried brain..
i also use magnesium for the jaw clench...
anything that can relieve the comedown is fine by me....

 

[BlueScorp|on]

Here is some helpful info I found thats related to 5-htp that every1 might be interested in reading:
From: http://www.biochemicals.com
SEROTONIN, TRYPTOPHAN, 5HTP, AND YOU
Each of these conditions has been associated with Serotonin deficiency. Premenstrual syndrome (PMS)
Insomnia
Fibromyalgia
Eating Disorders, Anorexia, and Bulimia
Obsessive-compulsive disorder
Obesity
Aggressive or violent behavior
New Evidence of Nerve Regeneration and Serotonin
As long as we can remember, medical researchers have insisted that when nerve cells die they are not replaced. But today, in laboratories around the world this belief is being proven wrong, and we find that the brain, like every other organ in the body, can and does grow new cells. Of great interest to researchers is the hippocampus, the region of the brain that is associated with learning and memory. In view of the fact that epidemic numbers of patients are complaining of memory loss, whether due to the effects of Ecstasy or other drugs, Alzheimer's Disease, or simple aging, researchers at Princeton University led by Dr. Stanley Jacobs have focused on factors that can actually stimulate cell growth in this region of the brain. Prominent among these factors is the neurotransmitter, Serotonin. Serotonin is produced in nature by metabolism of the essential amino acid, L-Tryptophan, or by metabolism of the plant extract, 5-Hydroxy-L-tryptophan.
Essential amino acids are critical for the formation of many life-giving biomolecules, including structural proteins, enzymes, and the neurotransmitters. For this reason, no other amino acid, vitamin, mineral, herb or drug can take the place of an essential amino acid. Furthermore, plasma amino-acid profiles of hundreds of patients demonstrate that natural precursors of serotonin may be lacking in the blood of most Americans. Despite the fact that Selective Serotonin Reuptake Inhibitors (SSRI's) are among the most heavily prescribed drugs in history, SSRI's cannot produce serotonin, and they cannot replace essential amino acids. This is why many patients on SSRI's continue to show deficiency symptoms.
Does Serotonin have Clinical Benefits?
Because Serotonin precursors are among the least abundant nutrients in our diet, it should be no surprise that supplemental essential amino acids have been widely used to correct Serotonin deficiencies by doctors in the United States and Europe for more than twenty years. Psychiatrists and medical doctors have enthusiastically recommended Serotonin precursors for relieving depression and carbohydrate cravings and normalizing sleep without side effects.
Although some symptoms of deficiency may disappear quickly, others may take time to show improvement. Essential amino acids are involved in a myriad of structural proteins and enzymes, as well as neurotransmitters, and so replacement may take time.
The fact that essential amino acids are building blocks for health is confirmed by the fact that amino acids are routinely added to baby food, where they are essential for growth, and to intravenous solutions (IV's), where they are essential for life.
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ITS ALL GOOD!!!

 

[Mr E. Moore]

I find 5-htp the day of the roll deadens the peak a little, I'm peaking but I don't get the lovey feelings and alot less rushes. But thats just me, for others they love it as a pre load. Post load though, this stuff is a god send beleive me, I hate coming down without it.

 

[Straylight]

Quote: "Post loading with another 100mgs on Sunday night...will help eliminate these symptoms of slightly reduced levels Seretonin synthesis (sic) due to neuron regeneration"
Sorry, K9, but from a medical point of view, you're talking shite. Neuron regeneration has nuffink 2 do wiv it.
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"You drive," he said. "I think there's something wrong with me." - Hunter S. Thompson, "Fear and Loathing in Las Vegas"

 

[*chaoscat*]

When ppl hear "preload" they seem to think that means a couple of hours before you drop. But you can "preload" weeks before.
Of everyone I've spoken to who's tried 5htp, none of them thought it gave them a good effect if they took it the same day they were going to drop. For some it does nothing, but personally I agree with bradan (and others) it makes a huge HUGE difference, both as a pre and postload.
May not make a difference to ppl who have just started dropping, but for me, the first time (preloading with 5htp) was "almost as good as the first time"!

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"Go peddle your kippers elsewhere clown" - Ren Hoek

 

[Fine wine]

Thanks for all the responses. My main concern though is that of longer term effects. At the moment I'm having 5-htp daily. Soon I'll cut that down to every second day. It has been two weeks now since I started and I'm definitely noticing improvements in areas of my daily life. Now I will wait a few months before I drop again (because I'm on an extended break) But I am planning to continue with 5-htp over this time. Will constantly using 5-htp in this way deaden my peak when I eventually come to drop again? I was reading somthing this morning on bluelight except I can't remember where it was. Someone said that the nuerons or something are getting excited by the 5-htp and long term use will deaden them or something. Is this true? I thought 5-htp was just supposed to build up seratonin levels. Has anyone here been using 5-htp daily (for reasons other than pre and post loading i.e. depression, sleeping patterns, appetite etc.) for a while and noticed that it reduces their peak?
Maybe I just misunderstood what that person said or maybe they were just speculating.
I thought I'd better post this though just to make sure as I certainly don't want to loose the ability to peak properly!

 

[NHL Guy]

straylight: what EXACTLY *does* it have to 'do with' then?
You jump in and dump on what others have put as their own offering but you know its a funny thing... ...I dont see YOU offering up your hallowed *medical* opinion on the matter. -oh wait, let me guess, you're from melbourne.
Having read what I posted immediately after I posted it, I realised that 'neuron regeneration' was not the most accurate term, in fact a better term would have been 'less neuron damage' due to 5HTP stop-gapping the drainage of the brain's natural chemical resources to provide it with a 'normal' level of seretonin, (much akin to stemming the damage from a jelyfish bite with an acid. or maybe that's just a little bit too *shite* for you to handle. BUT im afraid I cant put it in any simpler laymens terms) what I did NOT expect was to have what I said discounted on the basis of a pathetic and unsubstantiated flame from someone like yourself.
=MY Phrasing was wrong. I bow before you and grovel profusley.=
SHITE?
Grammatically maybe, but bio-chemically generally NOT.
-and besides, it was majorily an opinion based post...
(but who really cares about the opinion of a sydney sider.. i mean, My God.. back to farm..)
An offence without justification is a form of masturbationary(?) entertainment... if you are going to continue to do this then please, do it a home with a moist towel.
Cos it isnt worth the bandwidth im taking up to bite back.
[This message has been edited by #K9# (edited 01 August 2001).]
[This message has been edited by #K9# (edited 01 August 2001).]