N0 W4RN1NG
Bluelighter
I postulated on a few now defunct forums in 2015 that vendors should synth 4F-PVP. I explained my reasoning and posted proposed SAR and structural overlays.
What do you know, by the end of the month it was available. Many people did not enjoy it - it was nothing like a-PVP, but that was a good thing for me.
Now 4F-PHP has hit the scene, and I had to try some. It is less potent by weight, but otherwise indistinguishable. Quite enjoyable to me. I am on SSRI's and have been, forever. It is possible that there may be some undesirable serotonergic effects from 4F-pyrovalerones that I am impervious to, due to SSRIs.
Anyone else with prolonged SSRI use experience these? How do non-medicated folks react?
-NW
EDIT: I think that 2F-PxP (where 'x' denotes an alkyl chain 3-6 carbons in length) would be ideal research candidates. Extrapolating from both amphetamine and cathinone qSAR, which is only partially applicable to pyrovalerones of course. I would expect it(meaning 2F-PHP) to be MUCH more similar to "classic" NDRI PVPs than the 4F variants, yet much kinder. Speaking as someone who has done 2-FMC, 2-FA, and 2-FMA.
The des-keto, beta-dihydro homologues (fluoroprolintanes) should be even more predictable. I can say with a fair degree of certainty that a 3F substituent would work better in that case. Hmm, 3F-prolintane. I imagine it's not bad stuff!
What do you know, by the end of the month it was available. Many people did not enjoy it - it was nothing like a-PVP, but that was a good thing for me.
Now 4F-PHP has hit the scene, and I had to try some. It is less potent by weight, but otherwise indistinguishable. Quite enjoyable to me. I am on SSRI's and have been, forever. It is possible that there may be some undesirable serotonergic effects from 4F-pyrovalerones that I am impervious to, due to SSRIs.
Anyone else with prolonged SSRI use experience these? How do non-medicated folks react?
-NW
EDIT: I think that 2F-PxP (where 'x' denotes an alkyl chain 3-6 carbons in length) would be ideal research candidates. Extrapolating from both amphetamine and cathinone qSAR, which is only partially applicable to pyrovalerones of course. I would expect it(meaning 2F-PHP) to be MUCH more similar to "classic" NDRI PVPs than the 4F variants, yet much kinder. Speaking as someone who has done 2-FMC, 2-FA, and 2-FMA.
The des-keto, beta-dihydro homologues (fluoroprolintanes) should be even more predictable. I can say with a fair degree of certainty that a 3F substituent would work better in that case. Hmm, 3F-prolintane. I imagine it's not bad stuff!
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