• N&PD Moderators: Skorpio | thegreenhand

Ketamine salts solubility

(1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-piperidine-4-yl)-phenyl-ether.png


ANDREW_P.
(1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)-piperidine-4-yl)-phenyl-ether

1-((2-phenyl-1-methylethyl)-piperazine-4-yl)-1-phenyl-1-carbomethoxymethane.png


COSMO_D.
1-((2-phenyl-1-methylethyl)-piperazine-4-yl)-1-phenyl-1-carbomethoxymethane
 
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Harmane seems to be the most LSD-like of all harmala alkaloids. Unfortunately it's only a minor component in peganum harmala and probably difficult to separate.

1. A series of N-substituted tryptamines was compared with a series of beta-carbolines in rats trained to discriminate LSD (0.1 mg/kg) from saline.

2. Intermediate levels of substitution were elicited by MDMT (76.4% ), DMT (77.9% ), and DET (48.7% ). 6-F-DET produced 41.3% LSD-appropriate responding at a dose of 6.0 mg/kg but only 4 of 8 subjects completed the test session thus precluding statistical analysis. Bufotenine (25.8% ) also failed to substitute. Although none of the tryptamines substituted completely for LSD, the pattern of substitution is consonant with what is known of their activity in humans. MDMT, DMT, and DET are well established in the literature as hallucinogens but the same cannot be said for 6-F-DET and bufotenine.

3. Of the beta-carbolines tested, none substituted for LSD completely and only harmane elicited intermediate substitution (49.5% ). No significant generalization of the LSD stimulus to 6-methoxyharmalan, harmaline, or THBC was observed. Thus, in contrast to the tryptamines, scant ability to substitute for LSD was observed in the beta-carbolines tested.

4. Taken together, the present data indicate that the representative tryptamines employed in the present study exhibit greater similarity to the LSD stimulus than do representative beta-carbolines. The receptor interactions responsible for these differences remain to be determined.
 
1-(2-chloro-3,4-methylenedioxy-6-methoxyphenyl)-2-aminopropane.png


ARCTURIAN

1-(2-chloro-3,4-methylenedioxy-6-methoxyphenyl)-2-aminopropane

1-(2-iodo-3,4-methylenedioxy-6-methoxyphenyl)-2-aminopropane.png


DAVE


1-(2-iodo-3,4-methylenedioxy-6-methoxyphenyl)-2-aminopropane
 
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DOROTHY
1-(2-methyl-3,4-methylenedioxyphenyl)-2-aminopropane

Those Who Do Not Learn From Their Mistakes In Their Past Are Doomed To Repeat It.

1-(2-methyl-3,4-methylenedioxy-6-methoxyphenyl)-2-aminopropane.png


TODO
1-(2-methyl-3,4-methylenedioxy-6-methoxyphenyl)-2-aminopropane

1-(4-amyl-3,5-dimethoxyphenyl)-2-aminopropane.png


VALERO
1-(4-amyl-3,5-dimethoxyphenyl)-2-aminopropane
 
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1-(2-methylthio-3-chloro-4-bromophenyl)-1-methoxy-2-methylaminopropane.png


CAMPBELL'S
1-(2-methylthio-3-chloro-4-bromophenyl)-1-methoxy-2-methylaminopropane

If the N-methyl isn't active, the primary amine will be.

1-(2-methylthio-3-chloro-4-bromo-6-methoxyphenyl)-1-methoxy-2-aminopropane.png


LUIGI'S ALPHABET SOUP
1-(2-methylthio-3-chloro-4-bromo-6-methoxyphenyl)-1-methoxy-2-aminopropane

(2S)-1-phenyl-1-methoxy-2-propylaminopropane.png


PROFUSALEH
(2S)-1-phenyl-1-methoxy-2-propylaminopropane



1-(4-propylthiophenyl)-2-aminopropane.png


STEWIE
1-(4-propylthiophenyl)-2-aminopropane

(1-(3,4-methylenedioxyphenyl)-2-methylaminoprop-1-yl)-(2-methylphenyl)-ether.png


MIAMI
(1-(3,4-methylenedioxyphenyl)-2-methylaminoprop-1-yl)-(2-methylphenyl)-ether

(2S,5R,6R)-3-(%7B2-[(iminoethyl)amino]ethyl%7Dthio)-2-carbomethoxy-4-mercura-6-(%7B[3-phenyl-3-(3,4-methylenedioxyphenyl)-prop-2-yl]amino%7D)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene.png


THE MAD HATTER
(2S,5R,6R)-3-({2-[(iminoethyl)amino]ethyl}thio)-2-carbomethoxy-4-mercura-6-([3-phenyl-3-(3,4-methylenedioxyphenyl)-prop-2-yl]amino)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene

antibiotic

1-(2-bromo-3,4-methylenedioxy-6-methoxyphenyl)-2-methylaminopropane.png


MADONNA
1-(2-bromo-3,4-methylenedioxy-6-methoxyphenyl)-2-methylaminopropane

1-(2-methyl-3,4-methylenedioxy-6-methoxyphenyl)-2-ethylaminopropane.png


LOURDES
1-(2-methyl-3,4-methylenedioxy-6-methoxyphenyl)-2-ethylaminopropane

1-(2-methyl-6-methoxyphenyl)-2-aminopropane.png


SYFY
1-(2-methyl-6-methoxyphenyl)-2-aminopropane
 
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Not quite neuroscience, or pharmacology, but it does use organic chemistry. The relationship to learning systems in computation will likely have lots of crossover to neuroscience, especially as they work on these both by the methods of augmenting molecular configurations:

‘Designer molecules’ could create tailor-made quantum devices

020921_EC_quantum-molecule_feat-680x383.jpg

“A molecule with a central chromium ion (purple) can serve as a quantum bit, encoding information in the direction of its spin (indicated by its arrow in this illustration). Attached atoms (gray) alter the properties of the ion, allowing it to be manipulated by a laser (purple squiggle) and to emit light in response (red squiggle).”
 
1,1-di(indole-3-yl)-2-dimethylaminoethane.png


ROB
1,1-di(indole-3-yl)-2-dimethylaminoethane

(1,1-di(indole-3-yl)methyl)-(dimethylaminoethyl)-ether.png


ERNESTO
(1,1-di(indole-3-yl)methyl)-(dimethylaminoethyl)-ether

1-(indole-3-yl)-1-phenyl-2-aminopropane.png


MARILYN
1-(indole-3-yl)-1-phenyl-2-aminopropane

1-(3,4-methylenedioxyphenyl)-1-phenyl-2-aminopropane.png


ROCK
1-(3,4-methylenedioxyphenyl)-1-phenyl-2-aminopropane
 
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1-(2-ethyl-3,4-methylenedioxyphenyl)-2-methylaminopropane.png


EMERIL'S EMERALD
1-(2-ethyl-3,4-methylenedioxyphenyl)-2-methylaminopropane

1-(2-ethyl-3,4-methylenedioxyphenyl)-2-ethylaminopropane.png


NICOLE MILLER
1-(2-ethyl-3,4-methylenedioxyphenyl)-2-ethylaminopropane

These May Or May Not Be Active.

1-phenyl-2-propylaminopropane.png


JERRY JERICHO
1-phenyl-2-propylaminopropane

1-phenyl-1-carbomethoxy-1-(piperidine-4-yl)methane.png


ETON
1-phenyl-1-carbomethoxy-1-(piperidine-4-yl)methane

What Does It Do?
I Don't Know. What Do You Want It To Do?

3,7-dihydro-purine-2,6-dione.png


HAF CAF (xanthine)
3,7-dihydro-purine-2,6-dione
 
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Did I Lie To You?

1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-aminopropane.png


MAGIC POISON
1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-aminopropane

Life Of

1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-(methylamino)propane.png


BRIAN
1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-(methylamino)propane

1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-(ethylamino)propane.png


PALLAS 'SCARLET' ATHENA de Swainsboro
1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-(ethylamino)propane

1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-(propylamino)propane.png


CHRISTOPHER 'DINO' DANIEL BOWEN
1-(2,4,6-trioxo-1,3,5-triaza-3,5-dimethylcyclohexane-1-yl)-2-(propylamino)propane

Bon apetit!

1-(2,4,6-trioxo-1,3,5-triazacyclohexane-1-yl)-2-aminopropane.png


MONA
1-(2,4,6-trioxo-1,3,5-triazacyclohexane-1-yl)-2-aminopropane
 
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I wonder if there's an active xanthine, caffeine analog, that metabolizes into uric acid? What would you name that?
 
I'm not sure I understand your question.

1,1-di-(3,4-methylenedioxyphenyl)-2-aminopropane.png


JOEY
1,1-di-(3,4-methylenedioxyphenyl)-2-aminopropane
 
I'm not sure I understand your question.
I don't see how I could pose the question any simpler: If there was a xanthine whose metabolite in the human body by any pathway was uric acid for the molecule in question (the xanthine), what would you name such a compound. ;-j (it was a question posed to everyone though, not you alone, but any answer would suffice for me ;-j )

Screenshot-20210214-095820.png


Uric acid (urine):
Screenshot-20210214-100514.png
 
Not metabolically likely at all.

1-carbomethoxy-3-acetoxypropane.png


FRUITOPIA
1-carbomethoxy-3-acetoxypropane

-likely GHB prodrug
-probably smells gr8!
 
Methylene is R-CH2-R', where R stands for radical.

1-(4-bromo-2,5-dimethoxyphenyl)-1-(3,4-methylenedioxyphenyl)-2-aminopropane.png


ROEROE
1-(4-bromo-2,5-dimethoxyphenyl)-1-(3,4-methylenedioxyphenyl)-2-aminopropane

1-phenyl-1-(4-bromophenyl)-2-aminopropane.png


HOPE
1-phenyl-1-(4-bromophenyl)-2-aminopropane

1-(4-methoxyphenyl)-1-phenyl-2-aminopropane.png


CHAD
1-(4-methoxyphenyl)-1-phenyl-2-aminopropane

1,1-bis-(2,6-dimethoxy-4-bromophenyl)-2-aminopropane.png


TROY
1,1-bis-(2,6-dimethoxy-4-bromophenyl)-2-aminopropane
 
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Methylene is R-CH2-R', where R stands for radical
I meant any substitution coming off the nitrogen that eventually ended in one, not straight off of it.

Regardless, I wasn't trying to get in a debate about the viability, and which is why I did not limit the scope and present as example one specific instance of any sort, partly due to knowing that making it active would be a chore. I just thought the concept would make for a witty, facetious, name.

Namely (pun intended) It was a purposely abstract and flippant (much as this whole thread) request, not an invitation for analysis. ;-P I can't help but feel this thread needs more substance, setting any kind of precedent in that regard was my intention, broaden the spectrum of content a bit with some interaction, have something more than a series of stand alone posts.
 
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