• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe | Cheshire_Kat

2c-i question

Status
Not open for further replies.
N

New bee

Greenlighter
Joined
Aug 29, 2009
Messages
32
Staying away from ecstasy for a few months


But, I can get 2c-i and want to try it, should I stay away from it if I am trying to replace serotonin
 
^PD my friend, 2C-I is psychedelic.

I don't follow the OP; but, whatever, 2C-I won't deplete setotonin at all. It is, however, one of the most commonly known susbatnces for inducing HPPD which is not fun by all accounts.
 
Actually, I am pretty sure this is PD material.

However, we can talk about it here if you think this best fits here, MazDan.

I am pretty sure that the 2c series pharmacological effects are unknown at this point - though maybe they aren't.

If you're trying to replenish serotonin from frequent MDMA usage - then I would stick to not using any psychedelics at all.

OD -> PD
 
I don't think there's certain line as to say 2C-I is psychedelic and releases NO serotonin or MDMA is not psychedelic and releases lots of serotonin. I think quite a few psychedelics release some serotonin to a degree and many serotonin releasers have psychedelic effects. All my opinion of course. I haven't done tissue cultures where I've added the drugs in question and assayed the culture supernatant for fluctuation in neurotransmitters; just going on what feels like is going on in my own head.
 
I have nothing but subjective data to back my statements up with... but my e-pinion none the less.

I have noticed strong seratonin release from 2c-i... especially those with mood disorders and on mood stabilizers... it really throws them through the roof. Personally, it creates an intense egomania in me... One similar I get from SSRI's.
I certainly feel that 2c-i in particular certainly has a major effect on seratonin.

I've also noted that many people I have been with to take 2c-i have experienced some severe irritability to complete mood destabilization from it. Just a few days ago I had another trial with 15mg and I felt restless and worthless the next day.
I also seem to feel that rampant MDMA ABUSERS seem to love this compound because they can feel seratonin working... the last little bit they have up there.

Truly just my $.02... but I have personally taken 2c-i ~100 times and watched probably about a hundred people take it separately from me... and that's where I base my opinion from.
 
^ Same, it's all subjective from me but I feel all the halogenated 2C-x's cause some serotonin release. The positive push of euphoria from them does certainly feel mediated by serotonin not dissimilar to how MDMA works, but on a toned down scale with more 5-HT2 agonism causing psychedelic effects.
 
^Well even if 2c-i did release serotonin, I doubt it would have a noticeable effect, because your 5-HT receptors would already be agonized by molecules of 2c-i leaving no room for serotonin to bind. Pure speculation on my part though.

And FWIW, I've never thought 2c-i felt much like a monoamine releaser. Its definitely got a nice 'push' to it, but I don't think that necessarily correlates to monoamine release. I can feel similarities between MDMA and aMT, but I really don't feel many similarities between MDMA and 2C-I. MDMA feels much more "blown-out and electric" (the feeling I associate with serotonin release) while 2c-i lacks that quality.
 
Last edited:
Roger&Me said:
^Well even if 2c-i did release serotonin, I doubt it would have a noticeable effect, because your 5-HT receptors would already be agonized by molecules of 2c-i leaving no room for serotonin to bind. Pure speculation on my part though.
Click to expand...

that is assuming you have enough 2c-i in your brain to saturate the receptors, and as most don't take heroic doses, they still have some left to release some if it even did release it.... But its acts more on the receptors than causing serotonin to be pumped into your brain....

There are still plenty of receptors in your brain on an average recreational dose of 2c-i to pump out serotonin, just eat some MDMA with it.... My 2c-i + MDMA trip was one of the most unexpectedly balls to the wall trips i have had.... I need to find some more 2c-i to play with, none of the other 2c's i have tried synergized as beautifully as 2c-i with MDMA.... Dont get me wrong, they go rather well together but 2c-i +MDMA had me laid out in a chair for 5 hours tripping so hard i had no desire to stand up.....

Meh, i just told that story to show a point that at typical doses, there are still enough open receptors for a fuckton of serotonin to be pumped out....
 
wowww

My god, let me take a second to tell you all, that response was amazing.

I can't believe how much you all know and how much you were able to teach me.

Thank you for all your help, i've never dabbled in psychadelics, but I am really grateful for all your help.

keep up the good work!
 
uniter said:
^ Same, it's all subjective from me but I feel all the halogenated 2C-x's cause some serotonin release. The positive push of euphoria from them does certainly feel mediated by serotonin not dissimilar to how MDMA works, but on a toned down scale with more 5-HT2 agonism causing psychedelic effects.
Click to expand...

I imagine that the 5HT that 2C-I displaces might account for an increase in 5HT in some areas; which could be seen as a type of "release".
 
isotopic_parody said:
I have nothing but subjective data to back my statements up with... but my e-pinion none the less.

I have noticed strong seratonin release from 2c-i... especially those with mood disorders and on mood stabilizers... it really throws them through the roof. Personally, it creates an intense egomania in me... One similar I get from SSRI's.
I certainly feel that 2c-i in particular certainly has a major effect on seratonin.

I've also noted that many people I have been with to take 2c-i have experienced some severe irritability to complete mood destabilization from it. Just a few days ago I had another trial with 15mg and I felt restless and worthless the next day.
I also seem to feel that rampant MDMA ABUSERS seem to love this compound because they can feel seratonin working... the last little bit they have up there.

Truly just my $.02... but I have personally taken 2c-i ~100 times and watched probably about a hundred people take it separately from me... and that's where I base my opinion from.
Click to expand...

I have taken 2c-I, orally, about two or three dozen times. I've seen a few other people try it, but not too many other people. 2c-I definitely has the ability to make you irritable after the trip. the 2c series seems to do this for some reason. However, I didn't find it was too hard to "come back" from.

jamaica0535 said:
that is assuming you have enough 2c-i in your brain to saturate the receptors, and as most don't take heroic doses, they still have some left to release some if it even did release it.... But its acts more on the receptors than causing serotonin to be pumped into your brain....

There are still plenty of receptors in your brain on an average recreational dose of 2c-i to pump out serotonin, just eat some MDMA with it.... My 2c-i + MDMA trip was one of the most unexpectedly balls to the wall trips i have had.... I need to find some more 2c-i to play with, none of the other 2c's i have tried synergized as beautifully as 2c-i with MDMA.... Dont get me wrong, they go rather well together but 2c-i +MDMA had me laid out in a chair for 5 hours tripping so hard i had no desire to stand up.....

Meh, i just told that story to show a point that at typical doses, there are still enough open receptors for a fuckton of serotonin to be pumped out....
Click to expand...

I remember one person told me they ate a quarter gram of 2c-I...that's what I would consider a "heroic dose"... 8(
 
FWIW I don't believe 2CI releases serotonin. And let's remember, psychedelics don't bind to all 5ht receptors, so a serotonin release would still have an effect on those 5ht receptors that 2ci doesn't bind to.
 
Well 2C-I doesn't really release serotonin as is said before, but compared to 2C-B and the like it is a bit more straining. There have been multiple reports from people who stated that they felt cracked out the day after, it can be exhausting. But a full-on depression like with MDMA / ecstacy is unlikely.

I appreciate 2C-I but I'm not that crazy about it.

From the sounds of you I don't think you need to stay away from 2C-I for that particular reason. If you moderate your use you should really be fine.

Please take a look in the Big & Dandy 2C-I Thread
your question was answered yet and for further focus please go there. Welcome to bluelight!
 
Last edited:
Status
Not open for further replies.
Top