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Bupe 1mg sublingual suboxone this morning.. Safe to shoot dope ?

B

bubblesmoke

Bluelighter
Joined
Apr 8, 2009
Messages
203
Location
Los Angeles, California
So after a good weekend I was going to be out of dope for a couple days, so a friend gave me an 8mg suboxone film. Anyways, two days ago I cut it into pieces. Two days ago I took 2 mg. yesterday I took 2 mgs. Today I took 1 mg at 7:00 AM. Am I safe to shoot dope today ? Like this was my first time ever with bupe so I have no tolerance to that. Would I have any issues regarding blocking the effects of heroin ?
 
I thought precipitated withdrawal was suboxone after opiate ? I'm talking opiate after suboxone dose. I haven't done heroin in about 4 days.. But I did suboxone this morning
 
It will block the opiate as long as it is in your system. Doesn’t matter if you do the dope before or after.

Just wait till you get sick before you try to use another opiate.
 
Psychedelic Jay said:
Absolutely not.

You will be thrown straight into withdrawal. Wait until you start feeling sick to shoot again.
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This is not true. Precipitated withdrawal only happens when you have opiates in your system and then take suboxone, not the other way around as in the OP's case..

OP, in my experience, the blocking effect of suboxone is really limited under 2mg's. Metabolism is also an important factor. Some people metabolize drugs slower than others, in which case, they'd have to wait longer, while others like myself who have a fast metabolism, do not.

Waiting 24 hours would be your best bet, as chances are since you've taken suboxone for the past couple days and it's built up a bit in your system you wont get the full effect, but at a low dose like you're on, it will most likely not block much.
 
I don't know where you're getting your information but it's a good thing you came here first....

Considering that the precipitated withdrawals that everyone fears so much (and rightly so) are only an issue when going from full agonists --> buprenorphine, the only "issue" going from buprenorphine back to your DOC, be it heroin, oxycodone, hydromorphone, oxymorphone, morphine, etc...


Whatever your DOC, (in this case "dope" which I presume to mean heroin), extended use of buprenorphine is designed to jack up your tolerance through the roof due to it's incredibly high and notoriously underestimated potency.

Similar to the concept and prescribing practices behind a blocking dose of methadone hcl, half the point of the Opiate Replacement Therapy (ORT) is for your opioid tolerance to be too high for you to even consider attempting to break through your dose. This is because the amount of your DOC, in this case heroin, necessary to break through your buprenorphine dose, is supposed to make it pointless...

However in your case, 1mg buprenorphine taken via the sublingual Route of Administration means you'd be lucky to see 350 micrograms actually hit your bloodstream, which is by no means a blocking dose, but it may very well have had an influence on your tolerance.

So is it ever really "safe to shoot dope?" No, but to answer the question I think you meant to ask, is no, I don't think that an acute dose of 1mg buprenorphine via the SL route will significantly have an impact if you were to administer a full agonist of choice.

However this should go without saying that if you had the patience in you to wait another 12, even 24 hours for the remaining buprenorphine to get off your opioid receptors, it would give your DOC a snowballs chance in hell at binding to an opioid receptor producing your desired effects... Do not take this to mean that I condone the abuse of controlled substances, if it were up to me I would ask you to reconsider.
 
Psychedelic Jay said:
Absolutely not.

You will be thrown straight into withdrawal. Wait until you start feeling sick to shoot again.
Click to expand...

No he wont.

The real answer to this question is "ABSOLUTELY!"

I have never once in all my years of being on Suboxone (maybe 2 or 3 before i switched to Done) Ever been throwin into precip WD from ANYTHING but shooting subs.

I have literally taken suboxone in the morning and shot dope in the afternoon hundreds of times. And I used to take 4 or 8mg. I actually one time got pulled over before I copped one time and thought I was goin to jail so I took 8mg. Turned out they let me go with a warning, went and copped and shot dope not a half hour later and was fine.

Seriously, that whole precip WD thing is garbage. It just dont happen. At least it has never happened to me in my many years of shooting dope, or anyone I know. That is not the way the precip WD works.

All it will do is make it harder to get high.

If you aint on a long term regimen of sub and only took it a handful of times though your receptors shouldnt be saturated to the levels that a SMT patient would be. It will be harder to get high and oyu might not feel it as much as you want to but really the only risk is wasting money and dope. dont let anyone else tell u otherwise.
 
its safe to do dope, it might just take more than usual to get high since youve been on subs.. But I would say start with your usual dose bc you can always go up from there if your not high enough, you can't go down. Start slow and build up if your worried about it.
 
I don't have much experience in this area, but I'd recommend a lower starting dose to err on the side of caution. Remember that bupe is a partial agonist.

This will probably be ignored, but I'll chime in with some pharmacokinetics.

If I'm converting the time zones right, your last dose was 12 hours ago. Wiki lists the half life of buprenorphine as 20 - 70 hours with an average of 37 hours. Given the previous doses, you must have a decent amount left in you. Plugging in some numbers, I'm getting the following amounts, based on different possible half-lives of buprenorphine:

Half-life (hours) Dose Equivalent (mg)
20 1.8
37 2.5
70 3.1

NOTE:
These numbers don't take bioavailability in account, rather they're how much you would have to take right now to get to the amount currently in your body (starting from zero, assuming instant absorption). E.g, if your body metabolizes it at the average rate (1/2 removed every 37 hours), you could hypothetically take 2.5 mg for the first time now and you'd end up with the same amount that you actually have in your body now, given your previous use (again assuming that absorption is instant). I hope that makes some kind of sense. If not, completely ignore what I said (no information is safer than misinformation).
 
^Pretty much what everyone else who has any clue as to what they're talking about said

Someone posted the other day about trying to get high on 8mgs of suboxone and I said it wasn't possible for 36-48 hours....well, that's not even true...8 mgs will make it very difficult to get high for the first day, somewhat fuck it up on the second but it's till doable

1mg! ha! Unless you're doing really small amounts of dope you can plow right through that like nothing! Sure, if you took it 2-6 hours right after the sub you might notice a little bit of blocking, but not much!

PWD from doing full agonists on top of bupe just doesn't happen, it would be a fuckin bitch if it did!
 
Now, i am not exactly sure how safe this is, but i have numerous times while i was active in my addiction to opiates\opioids. When i have about a 160mg oxycodone tolorance i'd take a 4mg dose of the Pill form sub, yet still the same as the strips just the strips are much better tasting it isnt as strong tasting and dissolves faster, now anyway. as i said im not sure how safe this is, but even at that dose of oxy, if i were to take 4-8mg early in the morning i could eat 160 mgs and over ride the Bupe just make sure it's in full effect ( the bupe ) because precipitated WD's are HORRIBLE. Ok now With H, suboxone actually never worked for me until i lowered my tolorance, but now i've taken 6-8mgs in the morning trying to rid myself of withdrawls came up with money and done a nice shot and been fine, got high and all, i honestly did not notice a difference. Everyone seems to think its the Nalaxone as a blocker in Suboxone, i know thats why its in there but it seems to more of a deterant, but it's the bupe itself has the higher affinity for the receptor. Now, As i said, after taking the 8mg many hours later i have shot my normal H shot, and have felt it just as strong. now as i keep repeating, I am not sure how SAFE this is to do, but i know it works and you wont have to worry about the Precipitated WD's unless you take the sub dont wait until it comes on then shoot the H. Wait til it's under full effect as you said you took it in the morning and now want to do your normal shot this seems it would work fine, i know everyones body is different, but i sadly used to do this all the time... one thing though DO NOT SHOOT Suboxone OR Subutex without micron filtering it or actually that may not even be safe. Nothing worse than the HORRIBLE things that can happen from Shooting Pills into the wrong Veins ESPECIALLY without micron filtering.... BE SAFE and Happy Nodding. Hope i helped you out in this situation but as i always do. I repeat BE SAFE,

- B
 
ANewKindOfArmy said:
one thing though DO NOT SHOOT Suboxone OR Subutex without micron filtering it or actually that may not even be safe. Nothing worse than the HORRIBLE things that can happen from Shooting Pills into the wrong Veins ESPECIALLY without micron filtering....
Click to expand...

Haha, while that is true I think that for most junkies "in the moment" the real "nothing worse than HORRIBLE" is the feeling of "OH FUCK" when you shoot your sub and hit PWD like a mack truck collision. Obvioulsy in a harm reduction view shooting pills is horrible but when I read that I thought you was about to say dont shoot it because of the same reason I just said. Oh well, dont shoot it for both those reasons, I guess.

But yea...You know whats funny...I once got into an argument with my drug counselor at outpatient one time because I kept telling him that bupe has a higher affinity than naloxone and he refused to believe me. He kept being like "no, You mean NALOXONE does....You got it backwards." No matter how many times i explained the chemistry of it to him he would not listen and kept giving me the "run along now dumb little dopehead" treatment. Hah. It always pisses me off at how much some of these counselors who are supposed to be the ones teaching US shit, dont know half the shit we do about the way these substances work and that is a really sad thing if you think about it.

Anyways...I think the answer to this thread is pretty clear. Bombs away dude. By this time Im sure you already did it tho, so how did that work out for you?
 
Khadijah said:
Haha, while that is true I think that for most junkies "in the moment" the real "nothing worse than HORRIBLE" is the feeling of "OH FUCK" when you shoot your sub and hit PWD like a mack truck collision. Obvioulsy in a harm reduction view shooting pills is horrible but when I read that I thought you was about to say dont shoot it because of the same reason I just said. Oh well, dont shoot it for both those reasons, I guess.

But yea...You know whats funny...I once got into an argument with my drug counselor at outpatient one time because I kept telling him that bupe has a higher affinity than naloxone and he refused to believe me. He kept being like "no, You mean NALOXONE does....You got it backwards." No matter how many times i explained the chemistry of it to him he would not listen and kept giving me the "run along now dumb little dopehead" treatment. Hah. It always pisses me off at how much some of these counselors who are supposed to be the ones teaching US shit, dont know half the shit we do about the way these substances work and that is a really sad thing if you think about it.

Anyways...I think the answer to this thread is pretty clear. Bombs away dude. By this time Im sure you already did it tho, so how did that work out for you?
Click to expand...

Yeah, it's amazing how the doctors and so called "experts" don't even know shit about how bupe really works in actual practice. I've had doctors and the like swear that naloxone has a higher affinity than bupe, bupe can't be abused, can't be injected, that it takes away cravings completely, blah blah blah. All bull shit.
 
And God forbid you try to educate or even show them a new perspective on the medication they doll out like candy...

anyways, sorry to stray off topic.
 
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