Search results for query: psilocybin

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  1. Esperighanto

    Tryptamines Blue meanies

    ...so every 4 days you could, in theory, work your way up in half gram intervals to find the sweet spot. I usually advise people acquire psilocybin containing fungi in as large of an amount as possible, then homogenize it to try to get a feel for that batch subjectively. When I was...
  2. emkee_reinvented

    Psychedelics Mushroom Season

    Me neither only look-a likes Grass Bald Heads. These look almost identical but contain no Psilocybin, just cause gastric distress/ shitting and cramps. 😭 Even walked between the Sheep on Dikes, looking to the ground. Hoping i timed it right, none found. Though Amanita s, who are protected...
  3. P

    Opioids Oxycodone enhancement advice

    Out of curiosity is the amphetamine offsetting the cns depression here?
  4. Esperighanto

    Tryptamines Has anyone seen any real 4-aco-dmt?

    You should grab a copy of The Psilocybin Chef Cookbook, and then consider growing. I used to just eat fungi straight when I was cultivating, fuck it I'd eat the mycelium and just crunch away at rye grains some times. "The gang collectively decided this is wack", I was once told and I was asked...
  5. Pfafffed

    Miscellaneous Why Is Salvia so unhinged for a Psychedelic?,

    ...own class. It's a kappa opioid receptor agonist, and subjectively doesn't really feel anything like the serotonergic psychedelics (LSD, psilocybin, mescaline, etc.) If I had to compare it to anything, it would be a the dissociative ketamine, and that's an enormous stretch. Very few people...
  6. Phobos

    Tryptamines Psilocybin has no tolerance?

    ...you linked, they report achieving a 54% inhibition by using Theobromine, do you think that is a mild result? My speculation is that with Psilocybin and Psilocin a significant amount of the drug is metabolised in the stomach before ever being active and that is reinforced by my experiments...
  7. D

    Tryptamines Are Shrooms for difficult times only?

    can be very useful microdosing if you have no problems. It makes life more productive, more confident. I got straight A+ doing presentations at university while microdosing on psilocybin compared to getting D and failing when not microdosing lol
  8. JackARoe

    ☮ Social ☮ Interesting article on how Psilocybin can help people face death

    I love this stuff. Watching Netflix, How To Change Your Mind on psilocybin. The Michael Pollan special. There was a John Hopkins video also by people several months away from death that had found total peace after psilocybin. Pretty powerful. My only issue is the sterile environment they...
  9. Dextro .45

    Harm Reduction Hydromorph-CONTIN (2-3mg a day) and dextro-methamphetamine (10-20mg a day) - Slightly addicted! (Tincture bottles)

    ...with mental health issues (with all due respect) psychosis is a real issue from dopaminergic stimulants and other compounds like LSD & Psilocybin You're taking Canadian "Red Rockets" those fat massive red capsules Hydromorph-Contin 30mg XR beads.....ideally you're supposed to pulverize the...
  10. J

    Misc Migrains

    ...possible long term brain issues. Many psychedelic do, have permanent consequences like a drug felony, or messing your brain up but: But, psilocybin does work on cluster headaches. Which I think are not even touched by copious amounts of opiods, strong ones. They sometimes will actually...
  11. Esperighanto

    Phenethylamines 2C-B, worth trying on its own?

    ...see if I can find the case report, I think it was an NIH case study but I may not be correct. As far as compounds people hold dear, LSD, mescaline and psilocybin I also hold very dear but they've been illegal for over twice my lifetime where I live. Hasn't stopped access or use for me, at least.
  12. A

    Tryptamines Dose depended headache

    ...µg 1D-LSD which should convert to ~170µg LSD-25. According to conversion calculators, this should be about comparable to 4g dried standard psilocybin mushrooms. The trip was interesting, the headache also appeared (much later because LSD takes longer to fall off), it was somewhat comparable...
  13. Pissed_and_messed

    ☠ WARNING ☠ Warning: Over the counter “Amanita Gummies” contain 4-aco-dmt

    nothing like psilocybin. It is mostly just very natural relaxation, as far as I have made it with decarboxylated stuff. Muscimol is agonizing particularly gaba-a4 and a5 receptors apparently (same as zopiclone), in addition to muscarinic receptors, which explains its mildly tripping properties...
  14. fastandbulbous

    Tryptamines 5-MeO-aMT

    5-MeOAMT can be a bit rough on the stomach (& GI tract), but as had been said, about on a par with psilocybin (though much, much longer acting), with slightly different visuals. I found 2mg to be right for me as any higher and my guts detracted from any positive effect.
  15. emkee_reinvented

    Help! Upcoming trip - what to take?

    ...the experience is not. Why? Wild ones are no longer available to me, since they discovered fresh [dried is considered a preperation] 😂. Psilocybe shrooms were not illegal, only pure Psilocybine. Smartshops sucked up the market, and natural pickers went to the background/ dissapeared or...
  16. neversickanymore

    Miscellaneous Psilocybin mushroom strain and effects

    I'm seeing more discussion over psilocybin strains and effects. What difference in affects and effects if any do you feel individual strains have or don't?
  17. red22

    Pharmacology Info from Grok about LSD's phenethylamine moiety and noradrenergic potential

    ...studies or model this VTA-LC link further? To determine whether LSD’s phenethylamine moiety makes it more potentially noradrenergic than psilocybin, we need to compare their structures, focusing on the presence and role of the phenethylamine-like motif, and evaluate how this influences...
  18. Dextro .45

    Misc Anti-Depressants that have worked for you?

    ...properties 5) - Ketamine - TRMDD - dopamine increase, euphoric, anxiolytic, sedative anaesthetic (disassociate) 6) - LSD-25 & Psilocybin- low therapeutic doses of LSD or Psilocybin mushrooms have PROFOUND antidepressant properties. 7) - depo-Testosterone 200mg IM - very effective...
  19. paranoid android

    Tryptamines Shrooms vs LSD comparing doses

    Ive had penis envy and albino avery and the albino where alot stronger. Pretty sure of the dose of the acid i took to it was mind melting. But nowhere near the ego death experiences i had on shrooms
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