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Opioids Brain damage from opiate use

I just have to wonder if you're not on a high daily dose of opiates, if the same incidence of sleep apnea would occur... I've experienced sleep apnea twice in my life that I can remember, and I know that I wasn't on opiates for at least one occasion (not sure about the other).
 
would taking opiates with a stim prevent oxygen loss via decreasing the opiate effect on heartbeat?
 
been on opiates for 3 yrs (non-addict) about 2 times a week and i actually noticed i was getting smarter and more artistic, but then i started smoking weed and turned into a dumbass
 
@LSDMDMA most likely. increasing the breathing rate, opening airways

>>So this "brain damage" could come from any CNS depressant, and not just opiates>>

maybe there is something particular to opiates and how the muscles around the jaw (snoring, apnea) are controlled? i don't know. i'm in w/d, too lazy, so somebody else go find the study (referred to in an above post--see if there's a study indicating oxygen loss from good old alcy--i bet my hat there is)
 
This is interesting... I'm ordering a good pulse oximeter to check my O2 stats the next time I use opioids just to see
 
Safety of injectable opioid maintenance treatment for heroin dependence found blood oxygen concentrations on average fell to 78% (one was recorded at 52%) for up to 30 minutes after injecting pure heroin. Oxygen saturation below 86% for any length of time can cause problems.
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I don't have access. :( Anyway, they just measured blood oxygen concentrations right? Did they actually observe a decline in cognitive ability?

Cognitive impairment in methadone maintenance patients

Short term oxygen deprivation from non-fatal opiate overdose is known to cause some of this cognitive decline. But research from the prescribed heroin services shows that injected heroin at doses not considered "overdoses" can cause a short (5 - 30 minute) drop in blood oxygen saturation to levels that could cause some degree of brain and organ damage over time.
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Ok, so it appears this methadone study did measure cognitive ability. Was the change permanent? And the sample size was too small...


Didn't I just read a thread about opiates increasing cognitive ability? ( Edit: Never mind, I think I misunderstood what that thread was getting across. :o )


Thanks for sharing, flex.
 
I know this is old but should at the very least be saved from prunage, and is interesting enough to be worth bumping regardless.

Do they mention if this occurs with pain management sized doses, and doses taken to get high but low enough to exclude nodding?
 
One thing i do see is that heroin user genaraly look and act a few years younger then they are. So i think it sure slows down develpment a bit. Exp i'm 28 people think i'm 25/24. Do more heroin users notice the same?
 
oh for sure haze, there's been studies proven that once kids in particular start using drugs, their brain stops developing. so they only know so much. that's why so many users are fucking stupid
 
There's real evidence that Human Growth Hormone can help in the recovery process. I.e it promotes cell growth and division in the brain.
 
The brain damage from opiate use is devastating, as is any addiction. When you have an addiction your entire brain gets re wired so that when you finally get clean you are left with all sorts of problems.

The direct physical damage is largely dependent on how the user takes care of his/her self. Users tend to be very unhealthy but this is not a direct effect of the drugs.
 
oxyhydro said:
The brain damage from opiate use is devastating, as is any addiction. When you have an addiction your entire brain gets re wired so that when you finally get clean you are left with all sorts of problems.

The direct physical damage is largely dependent on how the user takes care of his/her self. Users tend to be very unhealthy but this is not a direct effect of the drugs.
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I certainly wouldn't say that the brain damage is devastating - significant yes. Devastating would imply serious cognitive deficits that would make day to day functioning impossible. Alcohol abuse has significant effects on the brain as do most psychostimulants (watch requiem for a dream and see Leto's mother by the end compared to Leto and Wayan).
The effects of opiate addiction mostly go unnoticed, they are however not to be underestimated on that im sure we agree
 
ive actually heard different things, like opiates are the one class of drug that is sorta healthy as long as you take care of yourself right. like heroin doesnt really effect the brain area too much, just moreso the body. the effects drugs like heroin are known for doing is on the body, its not really linked to the brain. it will stimulate weight loss, but i think as long as you eat plenty you will not get into really bad shape. but yes i would think this whole oxygen deprivation thing is true and can potentially cause some brain damage to the user. nothing major though, this is probably not at all significant enough to consider stopping opiate use just because of it.
 
when I was in a detox unit five years ago they gave me about 1/5 of the morphine I was used to. when I woke the doctor was staring at me and asked if I realized I had sleep apnea. I snore and spluttered on opiates for 9 years--before that I didn't snore or have sleep apnea (and I'm too thin for the apnea to be weight-related). I don't think I have it now that I've been abstinent for a while.

I do wonder if the brain just gets used to having less oxygen at night--it's hard to imagine that I've suffered major brain damage (but then, [drool], everything's hard to imagine). I functioned at the top of my class in my [professional] school and remembered details and names better than most. I still function at a pretty high level in my job, or at least I did until I hit zero in this goddamn detox and obtained the attention span of a fruit fly. Now I mostly sit and making whoosing sounds instead of working. I can make several, listen: whoooosh! whoosh! whooosh!
 
^Irrelevant I guess, but Mr. Mudd you sound just like my roomate I had in detox one time. He had the fucking WORST sleep apnea and snoring shit I have ever heard. Impossible for me to sleep. But then again kicking a large dope/benzo habit cold turkey didnt help me sleep either. Fucking nazi sons of bitches that place was.

/end rant.
 
I did my detox at home this time, out of compassion for any possible roommate. The snoring/apnea isn't bad in detox, but I literally can't lie still for about three hours when I lie down--STILL--and I'm abstinent almost four weeks. Trying not to wake up the roommate just makes the RLS worse.

Ok, so it wasn't just compassion for roommates--I also have a healthy hatred for detox rules. Every other wing of the hospital lets you have a tv, ipod, cigarette breaks outside--SOMETHING to pass the time. The detox wing here doesn't allow any of that so you have nothing to do but think about drugs. Goddamn human rights issue if you ask me. The rationale is that we might hang ourselves with our ear pods or something, or we might watch something inappropriate and set someone off. Yet visitors are allowed.

Odd that the upper body is fine in detox. Kicking junk would be far easier if I just amputated my legs. Hmm...


BrokedownPalace said:
^Irrelevant I guess, but Mr. Mudd you sound just like my roomate I had in detox one time. He had the fucking WORST sleep apnea and snoring shit I have ever heard. Impossible for me to sleep. But then again kicking a large dope/benzo habit cold turkey didnt help me sleep either. Fucking nazi sons of bitches that place was.

/end rant.
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