Well, I think you misunderstood my post. Sure it does require some basic chemistry before one can comprehend the principles in Mcmurry. But not really THAT much. This is a forum about drugs so I figured he wanted to learn something about organic chemistry as well.
I very well could have misread and I apologize if I came off as critical. I guess in my mind, a solid understanding of organic chemistry requires a very solid understand of general chemistry.
Obviously, for most people who are doing this for interest without instruction it would take quite a bit of time to get to point where one could understand and apply the principles of o-chem to medicinal chemistry (which I assume is the entire basis of this question).
And in that sense, yes, you are correct, a generally understanding of organic chemistry on a (for lack of a better term) "molecular level" would probably be suited here if the sole purpose is to understand medicinal chemistry. Yet, not
all of medicinal chemistry is organic; nitrous oxide is a simple but powerful inorganic anesthetic/psychoactive compound. My guess is that one would need to have at least a functional understanding of the basic principles of general chem, such as bonding-structure (i.e. valence/orbitals/carbon hybridization/energy/polarity/geometry/resonance.....the list goes on and on).
My point is, it is dangerous to "partially" learn something, skipping over what may seem "irrelevant". This may lead someone to believe that they understand "enough", which can be a problem when dealing with any form of chemistry in which an incomplete understanding, or a proper understanding misapplied, can result in injury or death. I did not abide by this rule; one of my interests from 8-18 was energetic chemistry, specifically that of high explosives. Did I read basic chemistry books and understand them; yes, for the most part. Did I properly apply what I learned; sort of. There is no textbook entitled
"An Adolescents Guide to Homemade High Explosive Synthesis (edition 1, Garage Laboratory)" Fortunately I never got seriously injured. I'm actually quite glad I was playing with compounds that were of high lethality; if I had been interested in drugs.........well.....there are fates far worse than death......
There are often questions on here that I sometimes feel like I have the knowledge to answer, but decide against doing so, because my knowledge of advanced medicinal chemistry is not exceptional. Sure, I taught two semesters of o-chem II (lecture and lab) at a local state university, but this is still very basic, and even with a very heavy curve students seemed to be struggling to pass (in one semester, the student with the highest non-curved percentage score was something like a 62%). I believe it was likely a combination of my amateurish teaching abilities and some rather slow students.
I am not saying that one cannot approach these subjects as an autodidact, much of what I "know" came to me first as an autodidact and was later clarified, corrected or re-affirmed in academia.
Again, I am not a great teacher, and I honestly don't know the best way to approach the following question:
what those hexagon thingys that make up chemical structures are all about