No problem at all
I was totally socially isolated due to severe depression/anxiety and I ended up with nobody IRL. The same month I started taking anti-depressants and was beginning to feel better my brother (only 16 months younger than me) starting inviting me to hang out with him and his friends (this was over the summer so no school for any of us). I still had a lot of social anxiety so everyone - like, everyone, including my parents - kept telling me to have a few drinks whenever I went out with people. I did and it worked wonders, but within a month I was drinking all day every day.
I had sex for the first time during that time.
I was then severely alcohol dependant for 8 years so was drunk like 98% of the time including every time I had sex.
I used most drugs during this time, too and after being very seriously ill in hospital and being given IV morphine 6 times a day for 11 weeks and then a high-dose Oxy script when I was discharged I got dependant on opioids, too.
I've always been high on opioids, drunk, or both whenever I've done anything sexual (the few times I was sober from alcohol and not high-high on opioids I was on some other drug).
I still drink alcohol very occasionally, but haven't been an alcohol for 4 years. Still dependant on opioids, but I also have severe chronic pain so I'll always need for for legit reason, too.
I was pretty old by todays standards when I lost my virginity. And then because I was drunk then and then every other time for several years, I guess I just get too anxious or my self-esteem is too low when I'm sober.
Probably has something to do with being raped as minor, too (I don't count that time as losing my virginity, rape is not sex) kinda makes me borderline-panicky when it comes to sex if I'm not sedated in some way.